Autologous Blood Transfusion in Pediatrics

PEDIATRICS ◽  
1990 ◽  
Vol 85 (1) ◽  
pp. 125-128
Author(s):  
LOUIS DEPALMA ◽  
NAOMI L. C. LUBAN
Keyword(s):  
Blood Transfusion ◽  
Blood Donation ◽  
Autologous Blood ◽  
Transmitted Disease ◽  
Autologous Blood Transfusion ◽  
Autologous Transfusion ◽  
Normovolemic Hemodilution ◽  
Acquired Immunodeficiency ◽  
Enclosed Space ◽  
Immunodeficiency Syndrome

Public concern about the risk of transfusion-transmitted disease, especially acquired immunodeficiency syndrome, has resulted in unprecedented growth in autologous blood donation programs.1 In addition to eliminating transfusion-transmitted viral diseases, the use of autologous blood transfusion avoids the risk of sensitization to red blood cell antigens and subsequent antibody formation. Although there are many published studies that illustrate both the effectiveness and safety of such programs,2-4 there are comparatively few that specifically address the pediatric patient. Autologous transfusion is defined as the collection and reinfusion of a patient's own blood. This may be accomplished by one of three modalities: (1) preoperative blood donation with subsequent blood bank storage and reinfusion during or following surgery; (2) acute normovolemic hemodilution, whereby blood is collected immediately preceding or following anesthetic induction and reinfused at the end of the surgical procedure; and (3) intraoperative and postoperative blood salvage, whereby blood shed into the operative field or enclosed space is collected, washed, and reinfused during or after surgery.

scholarly journals Transfusion of autologous blood

Medicina ◽  
2008 ◽  
Vol 44 (6) ◽  
pp. 482
Author(s):  
Audronė Veikutienė ◽  
Edmundas Širvinskas ◽  
Dalia Adukauskienė
Keyword(s):  
Blood Transfusion ◽  
Blood Donation ◽  
Autologous Blood ◽  
Allogeneic Blood Transfusion ◽  
Allogeneic Blood ◽  
Autologous Blood Transfusion ◽  
Donor Blood ◽  
Autologous Transfusion ◽  
Preoperative Autologous Blood Donation ◽  
Blood Salvage

Recently the use of allogeneic (donor) blood transfusion is widely accepted in the clinical practice. Despite of good quality and safety of preparation of allogeneic blood, there are some risks related with transfusion: hemolytic, febrile, and allergic reactions, transfusion related acute lung injury, negative immunomodulatory effect, transmission of infections diseases, dissemination and recurrence of cancer. This is why the indications for donor blood transfusion are restricted, so new safer methods are discovered to avoid or to decrease the heed for allogeneic blood transfusion. Nowadays, there is an increased interest in autologous blood transfusion as the most acceptable alternative to allogeneic blood transfusion. Autologous transfusion is the collection and reinfusion of the patient’s own blood (donor and recipient is the same person). Several types of autologous transfusion can be used: preoperative autologous blood donation, acute normovolemic hemodilution, intraoperative blood salvage, postoperative blood salvage. Neverless, autologous transfusion does not protect from all risks, it still remains the safest type of blood transfusion and is important in the strategy of blood conservation.

Experience of Autologous Blood Transfusion at a District General Hospital in Zambia

1994 ◽  
Vol 24 (3) ◽  
pp. 108-111 ◽  
Author(s):  
Winfred Manda ◽  
Gillian Duffy
Keyword(s):  
Blood Transfusion ◽  
Adverse Effects ◽  
Autologous Blood ◽  
District General Hospital ◽  
Autologous Blood Transfusion ◽  
Cell Salvage ◽  
Central Hospital ◽  
Autologous Transfusion ◽  
Practical Guidelines ◽  
Immunological Reactions

SUMMARY An Autologous Blood Transfusion Programme has been in operation at Ndola Central Hospital (NCH) since April 1992. This paper describes a method of cell salvage and reviews the two types of autologous transfusion [acute isovolaemic haemodilution (AIH) and cell salvage] practised over the 6 month period November 1992 to April 1993. No complications or adverse effects were encountered and the benefits include reduction of immunological reactions and transmission of infection, which are risks associated with homologous transfusion. There is need to minimize homologous transfusions because of these risks and hospitals should develop reasonable, practical guidelines for safer transfusion, including the use of autologous blood whenever possible.

scholarly journals Autologous blood transfusion in patients undergoing hip replacement surgery

2014 ◽  
Vol 67 (3-4) ◽  
pp. 101-107 ◽  
Author(s):  
Ivana Tesic ◽  
Jovan Sekulic ◽  
Vladimir Arbutinov ◽  
Dragana Popov ◽  
Dusan Velisavljev
Keyword(s):  
Blood Transfusion ◽  
Blood Donation ◽  
Autologous Blood ◽  
Oral Iron ◽  
Allogeneic Blood ◽  
Control Group ◽  
Autologous Blood Transfusion ◽  
Blood Products ◽  
Post Operative Period ◽  
Experimental Group

Introduction. Autologous blood transfusion is a set of procedures done in order to collect a patient?s blood and reinfuse it during or after a surgical intervention. The aim is to meet the patient?s need for blood products without allogeneic transfusion. By observing the hemoglobin and hematocrit values during blood donation in the pre-operative and post-operative period and by counting transfused blood units, the aim of this article was to detect whether there was any difference between the patients receiving autologous blood and those receiving only allogeneic blood. Material and Methods. This prospective study was performed at the General Hospital ?Djordje Joanovic? Zrenjanin from October 24th, 2011 to January 24th, 2013. The study included 60 patients who were divided into the experimental group of 30 patients who had been transfused autologous blood and the control group of 30 patients who had been transfused only allogeneic blood. Results. The average values of hemoglobin and hematocrit in the first and the second donation were 148.9 g/l and 44.2%, and 138.7 g/l and 40.8%, respectively. Oral iron preparation was given to 12 patients for two weeks before the first donation. The level of hemoglobin and hematocrit in both groups of patients had approximately the same values in the pre-operative and post-operative period. In the post-operative period, 2.53 units were transfused per patient in the experimental group and 3.73 units were transfused per patient in the control group. Conclusion. Administration of pre-operatively donated autogenous blood reduces the number of transfused deplasmatised erythrocytes units in comparison to the number of units transfused to the patients receiving only allogeneic blood products. The pre-operative use of oral iron preparations increases hemoglobin values significantly.

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