Neurotoxicity of Lorazepam in a Premature Infant

PEDIATRICS ◽  
1992 ◽  
Vol 89 (6) ◽  
pp. 1129-1130
Author(s):  
CATHERINE M. G. CRONIN

To the Editor.— Recently, I have observed several cases of stereotypic movements following injection of lorazepam in premature infants and wish to alert my colleagues to a potential cause of neurotoxicity. Case 1 CASE REPORTS A male neonate was born in a peripheral hospital at 24 weeks gestation. Apgar scores were 2 at 1 minute and 6 at 5 minutes. He weighed 680 g and was transferred to a tertiary care institution at 20 hours of life.

2018 ◽  
Vol 80 (01) ◽  
pp. 046-050 ◽  
Author(s):  
Zahrah Taufique ◽  
Nupur Bhatt ◽  
David Zagzag ◽  
Richard Lebowitz ◽  
Seth Lieberman

Objectives AlloDerm is an acellular dermal matrix often used for reconstruction throughout the body. AlloDerm has been shown to undergo revascularization when used to reconstruct soft tissue such as in abdominal wall reconstruction. In this study, the authors review the literature on revascularization of AlloDerm and demonstrate the histologic findings of AlloDerm after implantation during skull base reconstruction. Study Design Literature review and case reports. Setting Tertiary Care Institution Participants Patients from a tertiary care institution Main Outcome Measures Histologic slides are evaluated and compared with nonimplanted AlloDerm. Methods The authors review a case of explanted AlloDerm that had been used for skull base reconstruction after endoscopic skull base surgery. Results Upon reviewing the histologic slides of explanted AlloDerm to nonimplanted AlloDerm, we demonstrate revascularization of AlloDerm when used in skull base reconstruction. Representative slides will be included. Conclusions AlloDerm undergoes revascularization when used for skull base reconstruction.


2019 ◽  
Vol 64 (2) ◽  
pp. 106
Author(s):  
VengarakathPuthiyapura Reyila ◽  
Ambookken Betsy ◽  
Najeeba Riyaz ◽  
Sarita Sasidharanpillai ◽  
PentamVeil Beegum Sherjeena ◽  
...  

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