ORTHODONTIC PROBLEMS IN PEDIATRIC PRACTICE

PEDIATRICS ◽  
1952 ◽  
Vol 9 (6) ◽  
pp. 709-721
Author(s):  
T. M. GRABER

ONE of the most important phases of oral health is the form and function of the oral mechanism. That specialty of dentistry which has as its goal the correction of dental malformations and restoration of the continuity and proper function of the teeth and jaws is called orthodontics. While parents have long been concerned with the obvious esthetic disabilities of malposed teeth, the pathologic implications of these malposed teeth have been the primary concern of the orthodontist. Frequently, tooth malpositions or dental malocclusions reflect growth and developmental disturbances of the upper and lower jaws. Crooked teeth are unsightly, but more important, they probably are functioning improperly, or not at all, which seriously impairs the health and longevity of the teeth and investing tissues. Recent studies of facial growth indicate that dental malocclusions may be grouped in three morphologic categories, on the basis of jaw development and individual tooth malpositions. First, are those types of disturbances which are primarily skeletal in nature. These are problems where the maxilla or mandible has assumed an abnormal relationship to one another, usually through an upset in the timetable of normal development. The teeth in each dental arch may be normal in their position when compared to their respective jaws, but the abnormal jaw relationship means that the upper and lower teeth meet improperly during mastication, deglutition and speech. The second group consists of relatively local disturbances, with the teeth malposed, but with normal jaw relationship. The third group is a combination of the first two, with both improper jaw relationship and with teeth in abnormal positions. Within these three broad categories one may find all sorts of tooth malpositions and jaw relationships; the premaxillary segment may be displaced anteriorly, the whole lower dental arch may be retruded, the upper cuspids may be erupting in the palate, etc. Such conditions may be separate or occur in combination.

2020 ◽  
Vol 7 (4) ◽  
pp. 40
Author(s):  
Vasiliki Tsata ◽  
Dimitris Beis

The interactions of form and function have been the focus of numerous studies in the context of development and more recently regeneration. Our understanding on how cells, tissues and organs sense and interpret external cues, such as mechanical forces, is becoming deeper as novel techniques in imaging are applied and the relevant signaling pathways emerge. These cellular responses can be found from bacteria to all multicellular organisms such as plants and animals. In this review, we focus on hemodynamic flow and endothelial shear stress during cardiovascular development and regeneration, where the interactions of morphogenesis and proper function are more prominent. In addition, we address the recent literature on the role of extracellular matrix and fibrotic response during tissue repair and regeneration. Finally, we refer to examples where the integration of multi-disciplinary approaches to understand the biomechanics of cellular responses could be utilized in novel medical applications.


2018 ◽  
Vol 444 ◽  
pp. S219-S236 ◽  
Author(s):  
Katherine C. Woronowicz ◽  
Stephanie E. Gline ◽  
Safa T. Herfat ◽  
Aaron J. Fields ◽  
Richard A. Schneider

Author(s):  
Patricia G. Arscott ◽  
Gil Lee ◽  
Victor A. Bloomfield ◽  
D. Fennell Evans

STM is one of the most promising techniques available for visualizing the fine details of biomolecular structure. It has been used to map the surface topography of inorganic materials in atomic dimensions, and thus has the resolving power not only to determine the conformation of small molecules but to distinguish site-specific features within a molecule. That level of detail is of critical importance in understanding the relationship between form and function in biological systems. The size, shape, and accessibility of molecular structures can be determined much more accurately by STM than by electron microscopy since no staining, shadowing or labeling with heavy metals is required, and there is no exposure to damaging radiation by electrons. Crystallography and most other physical techniques do not give information about individual molecules.We have obtained striking images of DNA and RNA, using calf thymus DNA and two synthetic polynucleotides, poly(dG-me5dC)·poly(dG-me5dC) and poly(rA)·poly(rU).


2011 ◽  
Author(s):  
Scott Fluke ◽  
Russell J. Webster ◽  
Donald A. Saucier

2013 ◽  
Author(s):  
Joshua Wilt ◽  
William Revelle

Author(s):  
Barbara Schönig

Going along with the end of the “golden age” of the welfare state, the fordist paradigm of social housing has been considerably transformed. From the 1980s onwards, a new paradigm of social housing has been shaped in Germany in terms of provision, institutional organization and design. This transformation can be interpreted as a result of the interplay between the transformation of national welfare state and housing policies, the implementation of entrepreneurial urban policies and a shift in architectural and urban development models. Using an integrated approach to understand form and function of social housing, the paper characterizes the new paradigm established and nevertheless interprets it within the continuity of the specific German welfare resp. housing regime, the “German social housing market economy”.


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