Chlamydial Pneumonia in Infants
In 1977, Beem and Saxon (N Engl J Med 1977; 296: 306) reported on a new infant pneumonia syndrome caused by Chlamydia. Subsequently, it was noted that these infants with pneumonia were usually less than 6 months of age. When patients with chlamydial pneumonia were compared with infants with pneumonia of other etiologies, patients with chlamydial pneumonia had a syndrome characterized by long duration (more than 1 week), symptoms of cough and congestion, absence of fever, a staccatotype cough, rales, elevated eosinophil counts, and elevated immunoglobulins. Radiographic findings were not specific for chlamydial pneumonia but were very suggestive when they occurred in an infant with the classical clinical findings. In such patients, findings included bilateral hyperexpansion and diffuse infiltrates (interstitial or nodular). In addition, areas of atelectasis and coalescence were often seen, but pleural effusion and lobar consolidation were not.