scholarly journals Corrigendum to: Preventive Ventricular Tachycardia Ablation in Patients with Ischaemic Cardiomyopathy: Meta-analysis of Randomised Trials

2020 ◽  
Vol 8 (4) ◽  
pp. 304-304
Author(s):  
Roland R Tilz ◽  
Riccardo Proietti ◽  
Charlotte Eitel ◽  
Evgeny Lyan ◽  
Kivanc Yalin ◽  
...  
Keyword(s):  
Ventricular Tachycardia ◽  
Meta Analysis ◽  
Randomised Trials ◽  
Ventricular Tachycardia Ablation ◽  
Ischaemic Cardiomyopathy

scholarly journals Preventive Ventricular Tachycardia Ablation in Patients with Ischaemic Cardiomyopathy: Meta-analysis of Randomised Trials

2019 ◽  
Vol 8 (3) ◽  
pp. 173-179 ◽  
Author(s):  
Roland R Tilz ◽  
Charlotte Eitel ◽  
Evgeny Lyan ◽  
Kivanc Yalin ◽  
Spyridon Liosis ◽  
...  
Keyword(s):  
Ventricular Tachycardia ◽  
Catheter Ablation ◽  
Secondary Prevention ◽  
Meta Analysis ◽  
Randomised Trials ◽  
Icd Implantation ◽  
Icd Therapy ◽  
Number Of Patients ◽  
Significant Difference ◽  
Vt Ablation

Catheter ablation of ventricular tachycardia (VT) aims to treat the underlying arrhythmia substrate to prevent ICD therapies. The aim of this meta-analysis was to assess the safety and efficacy of VT ablation prior to or at the time of secondary prevention ICD implantation in patients with coronary artery disease, as compared with deferred VT ablation. Based on a systematic literature search, three randomised trials were considered eligible for inclusion in this analysis, and data on the number of patients with appropriate ICD shocks, appropriate ICD therapy, arrhythmic storm, death and major complications were extracted from each study. On pooled analysis, there was a significant reduction of appropriate ICD shocks (OR 2.58; 95% CI [1.54–4.34]; p<0.001) and appropriate ICD therapies (OR 2.04; 95% CI [1.15–3.61]; p=0.015) in patients undergoing VT ablation at the time of ICD implantation without significant differences with respect to complications (OR 1.39; 95% CI [0.43–4.51]; p=0.581). Mortality did not differ between both groups (OR 1.30; 95% CI [0.60–2.45]; p=0.422). Preventive catheter ablation of VT in patients with coronary heart disease at the time of secondary prevention ICD implantation results in a significant reduction of appropriate ICD shocks and any appropriate ICD therapy compared with patients without or with deferred VT ablation. No significant difference with respect to complications or mortality was observed between both treatment strategies.

scholarly journals Pre-procedural image-guided versus non-image-guided ventricular tachycardia ablation—a review

2020 ◽  
Vol 28 (11) ◽  
pp. 573-583 ◽  
Author(s):  
A. A. Hendriks ◽  
Z. Kis ◽  
M. Glisic ◽  
W. M. Bramer ◽  
T. Szili-Torok
Keyword(s):  
Overall Survival ◽  
Ventricular Tachycardia ◽  
Meta Analysis ◽  
Bibliographic Databases ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Ventricular Tachycardia Ablation ◽  
Image Guided ◽  
Vt Ablation

Abstract Background Magnetic resonance imaging and computed tomography in patients with ventricular tachycardia (VT) after myocardial infarction (MI) helps to delineate scar from healthy tissue. Image-guided VT ablation has not yet been studied on a large scale. Objective The aim of the meta-analysis was to compare the long-term outcome of image-guided VT ablation with a conventional approach for VT after MI. Methods Eight electronic bibliographic databases were searched to identify all relevant studies from 2012 until 2018. The search for scientific literature was performed for studies that described the outcome of VT ablation in patients with an ischaemic substrate. The outcome of image-guided ablation was compared with the outcome of conventional ablations. Results Of the 2990 citations reviewed for eligibility, 38 articles—enrolling a total of 7748 patients—were included into the meta-analysis. Five articles included patients with image-guided ablation. VT-free survival was 82% [74–90] in the image-guided VT ablation versus 59% [54–64] in the conventional ablation group (p < 0.001) during a mean follow-up of 35 months. Overall survival was 94% [90–98] in the image-guided versus 82% [76–88] in the conventional VT ablation group (p < 0.001). Conclusions Image-guided VT ablation in ischaemic VT was associated with a significant benefit in VT-free and overall survival as compared with conventional VT ablation. Visualising myocardial scar facilitates substrate-guided ablation procedures, pre-procedurally and by integrating imaging during the procedure, and may consequently improve long-term outcome.

scholarly journals P291Imaging guided versus non imaging guided ventricular tachycardia ablation - a meta-analysis

EP Europace ◽  
2018 ◽  
Vol 20 (suppl_1) ◽  
pp. i41-i41 ◽  
Author(s):  
A A Hendriks ◽  
Z Kis ◽  
M Glisic ◽  
W M Bramer ◽  
T Szili-Torok
Keyword(s):  
Ventricular Tachycardia ◽  
Meta Analysis ◽  
Ventricular Tachycardia Ablation

scholarly journals Complication rates following ventricular tachycardia ablation in ischaemic and non-ischaemic cardiomyopathies: a systematic review

2021 ◽  
Author(s):  
Wern Yew Ding ◽  
Charles M. Pearman ◽  
Laura Bonnett ◽  
Ahmed Adlan ◽  
Shui Hao Chin ◽  
...  
Keyword(s):  
Ventricular Tachycardia ◽  
Catheter Ablation ◽  
Vascular Complications ◽  
Major Complication ◽  
Complication Rates ◽  
Ventricular Tachycardia Ablation ◽  
Ischaemic Cardiomyopathy ◽  
Cerebrovascular Events ◽  
Acute Complications ◽  
Vt Ablation

Abstract Background Catheter ablation of ventricular tachycardia (VT) is associated with potential major complications, including mortality. The risk of acute complications in patients with ischaemic cardiomyopathy (ICM) and non-ischaemic cardiomyopathy (NICM) has not been systematically evaluated. Methods PubMed was searched for studies of catheter ablation of VT published between September 2009 and September 2019. Pre-specified primary outcomes were (1) rate of major acute complications, including death, and (2) mortality rate. Results A total of 7395 references were evaluated for relevance. From this, 50 studies with a total of 3833 patients undergoing 4319 VT ablation procedures fulfilled the inclusion criteria (mean age 59 years; male 82%; 2363 [62%] ICM; 1470 [38%] NICM). The overall major complication rate in ICM cohorts was 9.4% (95% CI, 8.1–10.7) and NICM cohorts was 7.1% (95% CI, 6.0–8.3). Reported complication rates were highly variable between studies (ICM I2 = 90%; NICM I2 = 89%). Vascular complications (ICM 2.5% [95% CI, 1.9–3.1]; NICM 1.2% [95% CI, 0.7–1.7]) and cerebrovascular events (ICM 0.5% [95% CI, 0.2–0.7]; NICM, 0.1% [95% CI, 0–0.2]) were significantly higher in ICM cohorts. Acute mortality rates in the ICM and NICM cohorts were low (ICM 0.9% [95% CI, 0.5–1.3]; NICM 0.6% [95% CI, 0.3–1.0]) with the majority of overall deaths (ICM 75%; NICM 80%) due to either recurrent VT or cardiogenic shock. Conclusion Overall acute complication rates of VT ablation are comparable between ICM and NICM patients. However, the pattern and predictors of complications vary depending on the underlying cardiomyopathy.

A meta-analysis of manual versus remote magnetic navigation for ventricular tachycardia ablation

2017 ◽  
Vol 49 (3) ◽  
pp. 227-235 ◽  
Author(s):  
Mohit K. Turagam ◽  
Donita Atkins ◽  
Roderick Tung ◽  
Moussa Mansour ◽  
Jeremy Ruskin ◽  
...  
Keyword(s):  
Ventricular Tachycardia ◽  
Meta Analysis ◽  
Magnetic Navigation ◽  
Remote Magnetic Navigation ◽  
Ventricular Tachycardia Ablation

scholarly journals Multimodality Imaging to Guide Ventricular Tachycardia Ablation in Patients with Non-ischaemic Cardiomyopathy

2020 ◽  
Vol 8 (4) ◽  
pp. 255-264
Author(s):  
Ling Kuo ◽  
Jackson J Liang ◽  
Saman Nazarian ◽  
Francis E Marchlinski
Keyword(s):  
Ventricular Tachycardia ◽  
Multimodal Imaging ◽  
Current Knowledge ◽  
Multimodality Imaging ◽  
Effective Treatment Option ◽  
Ventricular Tachycardia Ablation ◽  
Ischaemic Cardiomyopathy ◽  
Vt Ablation ◽  
Procedural Planning

Catheter ablation is an effective treatment option for ventricular tachycardia (VT) in patients with non-ischaemic cardiomyopathy (NICM). The heterogeneous nature of NICM aetiologies and VT substrate in patients with NICM play a role in long-term ablation outcomes in this population. Over the past decades, more precise identification of NICM aetiologies and better characterisation of various substrates have been made. Application of multimodal imaging has greatly contributed to the accurate diagnosis of NICM subtypes and improved VT ablation strategies. This article summarises the current knowledge of multimodal imaging used in the characterisation of non-ischaemic NICM substrates, procedural planning and image integration for the optimisation of VT ablation.

Abstract 15656: Manual vs Remote Magnetic Navigation for Ventricular Tachycardia Ablation: A Meta-analysis

Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Ghulam Murtaza ◽  
Mohit K Turagam ◽  
Jalaj Garg ◽  
Krishna Akella ◽  
Donita Atkins ◽  
...  
Keyword(s):  
Ventricular Tachycardia ◽  
Meta Analysis ◽  
Cochrane Review ◽  
Final Analysis ◽  
Magnetic Navigation ◽  
Continuous Variables ◽  
Remote Magnetic Navigation ◽  
Ventricular Tachycardia Ablation ◽  
Vt Ablation ◽  
Mean Differences

Introduction: The role of remote magnetic navigation (RMN) for ventricular tachycardia (VT) ablation is not well established. In this meta- analysis, we aim to evaluate the safety and efficacy of RMN vs manual navigation (MAN) for VT ablation. Methods: A comprehensive literature search in PubMed, Google Scholar and Cochrane Review from inception till November 9th, 2019 was performed. Studies reporting clinical outcomes comparing MAN vs RMN were included. Two investigators independently extracted the data and individual quality assessment was performed. Results were expressed as odds ratio (OR) for dichotomous outcomes and mean differences (MD) for continuous variables with 95% confidence intervals (CI). Results: Eight studies including a total of 861 patients (475 in RMN arm and 386 in MAN arm) were included in the final analysis. VT recurrence was significantly lower with RMN compared with MAN (OR 0.65, 95% CI 0.48-0.88, p= 0.005). Acute procedural success was significantly higher with RMN (OR 2.21, 95% CI 1.51-3.23, p < 0.0001). Total procedure time [MD -8.83, 95% CI -17.72- 0.05, p=0.05], fluoroscopy time [MD -10.24, 95% CI -12.28- -8.19, p= 0.00001), and complications [OR 0.36, 95% CI 0.18- 0.72, p= 0.003] were significantly lower in RMN compared to MAN. Conclusion: Results of our meta-analysis indicate that RMN is safer and more effective than MAN in patients with VT undergoing ablation. Further, randomized studies are needed to validate these findings.

Sign in / Sign up

Export Citation Format

Share Document