Controlling Blood Pressure without Drugs – Developing New Strategies

2010 ◽  
Vol 6 (2) ◽  
pp. 18
Author(s):  
Markus P Schlaich ◽  
Murray D Esler ◽  
◽  
Keyword(s):  
Blood Pressure ◽  
Blood Pressure Control ◽  
Pressure Control ◽  
Therapeutic Strategies ◽  
Novel Device ◽  
Major Player ◽  
Treatment Of Hypertension ◽  
Sympathetic Nervous ◽  
Optimal Blood Pressure ◽  
New Strategies

Non-optimal blood pressure is the leading cause of death globally, and each year is responsible for seven million deaths. Current therapeutic strategies for hypertension are mainly based on lifestyle interventions and pharmacological approaches, but rates of blood pressure control remain unsatisfactory and additional options are required. In this context, novel device-based approaches specifically targeting the sympathetic nervous system as a major player in blood pressure control have recently been tested clinically with promising results. Device-based approaches may provide additional and more effective treatment of hypertension and its adverse consequences in the future.

Controlling Blood Pressure without Drugs – Developing New Strategies

2011 ◽  
Vol 3 (1) ◽  
pp. 37
Author(s):  
Markus P Schlaich ◽  
Murray D Esler ◽  
◽  
Keyword(s):  
Blood Pressure ◽  
Blood Pressure Control ◽  
Pressure Control ◽  
Therapeutic Strategies ◽  
Novel Device ◽  
Major Player ◽  
Treatment Of Hypertension ◽  
Sympathetic Nervous ◽  
Optimal Blood Pressure ◽  
New Strategies

Non-optimal blood pressure is the leading cause of cardiovascular-related death worldwide, and each year is responsible for seven million deaths. Current therapeutic strategies for hypertension are mainly based on lifestyle interventions and pharmacological approaches, but rates of blood pressure control remain unsatisfactory and additional options are required. In this context, novel device-based approaches specifically targeting the sympathetic nervous system as a major player in blood pressure control have recently been tested clinically with promising results. Device-based approaches may provide additional and more effective treatment of hypertension and its adverse consequences in the future.

Early, Optimal Blood Pressure Control for High-risk Patients

2006 ◽  
Vol 2 (1) ◽  
pp. 25
Author(s):  
Peter M Nilsson ◽  
Keyword(s):  
Blood Pressure ◽  
High Risk ◽  
Blood Pressure Control ◽  
Pressure Control ◽  
High Risk Patients ◽  
Risk Patients ◽  
Optimal Blood Pressure

Interactions between ANG II, sympathetic nervous system, and baroreceptor reflexes in regulation of blood pressure

1992 ◽  
Vol 262 (6) ◽  
pp. E763-E778 ◽  
Author(s):  
I. A. Reid
Keyword(s):  
Blood Pressure ◽  
Nervous System ◽  
Sympathetic Nervous System ◽  
Blood Pressure Control ◽  
Cardiovascular Responses ◽  
Pressure Control ◽  
Ang Ii ◽  
Arterial Blood ◽  
Baroreceptor Reflexes ◽  
Sympathetic Nervous

The renin-angiotensin system plays an important role in the regulation of arterial blood pressure and in the development of some forms of clinical and experimental hypertension. It is an important blood pressure control system in its own right but also interacts extensively with other blood pressure control systems, including the sympathetic nervous system and the baroreceptor reflexes. Angiotensin (ANG) II exerts several actions on the sympathetic nervous system. These include a central action to increase sympathetic outflow, stimulatory effects on sympathetic ganglia and the adrenal medulla, and actions at sympathetic nerve endings that serve to facilitate sympathetic neurotransmission. ANG II also interacts with baroreceptor reflexes. For example, it acts centrally to modulate the baroreflex control of heart rate, and this accounts for its ability to increase blood pressure without causing a reflex bradycardia. The physiological significance of these actions of ANG II is not fully understood. Most evidence indicates that the actions of ANG to enhance sympathetic activity do not contribute significantly to the pressor response to exogenous ANG II. On the other hand, there is considerable evidence that the actions of endogenous ANG II on the sympathetic nervous system enhance the cardiovascular responses elicited by activation of the sympathetic nervous system.

scholarly journals Risk factors of uncontrolled hypertension in urban slums of Central India : A Community health worker based two-year follow up

2021 ◽  
Author(s):  
Abhijit P Pakhare ◽  
Anuja Lahiri ◽  
Neelesh Shrivastava ◽  
N Subba Krishna ◽  
Ankur Joshi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Cardiovascular Diseases ◽  
Blood Pressure Control ◽  
Pressure Control ◽  
Urban Slum ◽  
Primary Care Providers ◽  
Uncontrolled Hypertension ◽  
Optimal Blood Pressure

AbstractBackgroundHypertension is a leading cause of cardiovascular diseases its control is poor. There exists heterogeneity in levels of blood-pressure control among various population sub-groups. Present study conducted in framework of National Program for prevention and control of cancer, diabetes, cardiovascular diseases and stroke (NPCDCS) in India, aims to estimate proportion of optimal blood pressure control and identify potential risk factors pertaining uncontrolled hypertension consequent to initial screening.MethodsWe conceived a cohort of individuals with hypertension confirmed in a baseline screening in sixteen urban slum clusters of Bhopal (2017-2018). Sixteen Accredited Social Health Activists (ASHAs) were trained from within these urban slum communities. Individuals with hypertension were linked to primary care providers and followed-up for next two years. Obtaining optimal blood-pressure control (defined as SBP< 140 and DBP<90 mm of Hg) was a key outcome. Role of baseline anthropometric, and CVD risk factors was evaluated as predictors of blood-pressure control on univariate and multivariate analysis.ResultsOf a total of 6174 individuals, 1571 (25.4%) had hypertension, of which 813 were previously known and 758 were newly detected during baseline survey. Two year follow up was completed for 1177 (74.9%). Blood-pressure was optimally controlled in 301 (26%) at baseline, and in 442 (38%) individuals at two years (absolute increase of 12%; 95% CI 10.2-13.9). Older age, physical-inactivity, higher BMI and newly diagnosed hypertension were significantly associated with uncontrolled blood-pressure.ConclusionsIn the current study we found about six of every ten individuals with hypertension were on-treatment, and about four were optimally controlled. These findings provide a benchmark for NPCDCS, in terms of achievable goals within short periods of follow-up.

Burning issues in blood pressure control

2019 ◽  
Vol 61 (2) ◽  
pp. 24-26
Author(s):  
J. A. Ker ◽  
K. Outhoff
Keyword(s):  
Blood Pressure ◽  
Blood Pressure Control ◽  
Treatment Guidelines ◽  
Premature Death ◽  
Pressure Control ◽  
Arterial Disease ◽  
Elevated Blood ◽  
Optimal Blood Pressure ◽  
Peripheral Arterial ◽  
Ageing Populations

Globally more than 1 billion people have hypertension and it is predicted that because of ageing populations and increasing sedentary lifestyles, this figure will rise to about 1.5 billion by 2025. Elevated blood pressure (BP) is the leading cause of premature death and morbidity due to stroke and ischemic heart disease. Hypertension is also a major risk factor for heart failure, atrial fibrillation, chronic kidney disease, peripheral arterial disease and cognitive decline. This article discusses the current evidencebased treatment guidelines and pressing temporal issues in optimal blood pressure control.

scholarly journals Electronic Monitoring of Adherence, Treatment of Hypertension, and Blood Pressure Control

2012 ◽  
Vol 25 (1) ◽  
pp. 54-59 ◽  
Author(s):  
H. A. W. v. Onzenoort ◽  
W. J. Verberk ◽  
A. A. Kroon ◽  
A. G. H. Kessels ◽  
C. Neef ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Blood Pressure Control ◽  
Electronic Monitoring ◽  
Pressure Control ◽  
Treatment Of Hypertension

scholarly journals Optimal blood pressure control in treated hypertensive patients. Report from the Department of Health Hypertension Care Computing Project (DHCCP).

Circulation ◽  
1994 ◽  
Vol 90 (1) ◽  
pp. 225-233 ◽  
Author(s):  
C J Bulpitt ◽  
A J Palmer ◽  
A E Fletcher ◽  
D G Beevers ◽  
E C Coles ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Blood Pressure Control ◽  
Pressure Control ◽  
Hypertensive Patients ◽  
Department Of Health ◽  
Optimal Blood Pressure
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