Membrane fluidity and lipid composition in clinical isolates ofCandida albicansisolated from AIDS/HIV patients

2008 ◽  
Vol 55 (1) ◽  
pp. 73-73
Author(s):  
N. Mishra ◽  
T. Prasad ◽  
N. Sharma ◽  
Ali Lattif ◽  
R. Prasad ◽  
...  
Keyword(s):  
Membrane Fluidity ◽  
Lipid Composition ◽  
Clinical Isolates ◽  
Hiv Patients

Membrane fluidity and lipid composition in clinical isolates ofCandida albicansisolated from AIDS/HIV patients

2007 ◽  
Vol 54 (4) ◽  
pp. 367-377 ◽  
Author(s):  
N. Mishra ◽  
T. Prasad ◽  
N. Sharma ◽  
R. Prasad ◽  
D. Gupta
Keyword(s):  
Membrane Fluidity ◽  
Lipid Composition ◽  
Clinical Isolates ◽  
Hiv Patients

Dietary Selenium or Zinc Supplementation Restores Brain Lipid Composition and Membrane Fluidity in Protein-Undernourished Rats

2016 ◽  
Vol 38 (6) ◽  
pp. 397-406
Author(s):  
Olusegun L. Adebayo ◽  
Bamidele A. Salau ◽  
Rajat Sandhir ◽  
Gbenga A. Adenuga
Keyword(s):  
Membrane Fluidity ◽  
Lipid Composition ◽  
Zinc Supplementation ◽  
Protective Role ◽  
Membrane Lipid ◽  
Limited Information ◽  
Total Lipids ◽  
Major Focus ◽  
Membrane Lipid Composition

Studies have shown that protein undernutrition (PU) modifies the membrane lipid composition in the intestine and liver, as well as in plasma and other areas. However, there is limited information on the effect of PU on synaptosomal membrane lipid composition and fluidity and the protective role of selenium (Se) and zinc (Zn), which is a major focus of the present study. For 10 weeks, rats were fed diets containing 16% casein, which constituted the adequate protein diet, or 5% casein, representing the PU diet. The animals were supplemented with Se and Zn at a concentration of 0.15 and 227 mg L-1, respectively, in drinking water for 3 weeks. The results showed a significant increase in total lipids, glycolipids, triglycerides, cholesterol, and the cholesterol/phospholipid (Chol/PL) ratio, and a significant reduction in phospholipids and membrane fluidity. Se and Zn supplementation to PU rats, however, significantly lowered total lipids, glycolipids, triglycerides, cholesterol, and the Chol/PL ratio, while phospholipids and membrane fluidity were significantly restored. It is concluded that a perturbed lipid composition induced by PU affects the membrane structure and fluidity, which in turn influences membrane functions. The study suggests that Se and Zn supplementation might be beneficial in restoring the lipid dyshomeostasis associated with PU.

Ximelagatran increases membrane fluidity and changes membrane lipid composition in primary human hepatocytes

2009 ◽  
Vol 23 (7) ◽  
pp. 1305-1310 ◽  
Author(s):  
Odile Sergent ◽  
Kim Ekroos ◽  
Luz Lefeuvre-Orfila ◽  
Mary Rissel ◽  
Gun-Britt Forsberg ◽  
...  
Keyword(s):  
Membrane Fluidity ◽  
Lipid Composition ◽  
Membrane Lipid ◽  
Human Hepatocytes ◽  
Membrane Lipid Composition ◽  
Primary Human Hepatocytes

Decreased Erythrocyte Membrane Fluidity and Altered Lipid Composition in Human Liver Disease

1981 ◽  
Vol 60 (3) ◽  
pp. 2P-2P ◽  
Author(s):  
J. S. Owen ◽  
K. R. Bruckdorfer ◽  
R. C. Day ◽  
N. McIntyre
Keyword(s):  
Liver Disease ◽  
Membrane Fluidity ◽  
Erythrocyte Membrane ◽  
Lipid Composition ◽  
Human Liver ◽  
Erythrocyte Membrane Fluidity ◽  
Human Liver Disease ◽  
Altered Lipid

scholarly journals Adaptation of Escherichia coli O157:H7 to pH Alters Membrane Lipid Composition, Verotoxin Secretion, and Resistance to Simulated Gastric Fluid Acid

2004 ◽  
Vol 70 (6) ◽  
pp. 3500-3505 ◽  
Author(s):  
Hyun-Gyun Yuk ◽  
Douglas L. Marshall
Keyword(s):  
Escherichia Coli ◽  
Membrane Fluidity ◽  
Lipid Composition ◽  
Vaccenic Acid ◽  
Acid Resistance ◽  
Gastric Fluid ◽  
Membrane Lipid ◽  
Simulated Gastric Fluid ◽  
Acidic Ph ◽  
Membrane Lipid Composition

ABSTRACT The influence of adaptation to pH (from pH 5.0 to 9.0) on membrane lipid composition, verotoxin concentration, and resistance to acidic conditions in simulated gastric fluid (SGF) (pH 1.5, 37�C) was determined for Escherichia coli O157:H7 (HEC, ATCC 43895), an rpoS-deficient mutant of ATCC 43895 (HEC-RM, FRIK 816-3), and nonpathogenic E. coli (NPEC, ATCC 25922). Regardless of the strain, D values (in SGF) of acid-adapted cells were higher than those of non-acid-adapted cells, with HEC adapted at pH 5.0 having the greatest D value, i.e., 25.6 min. Acid adaptation increased the amounts of palmitic acid (C16:0) and decreased cis-vaccenic acid (C18:1ω7c) in the membrane lipids of all strains. The ratio of cis-vaccenic acid to palmitic acid increased at acidic pH, causing a decrease in membrane fluidity. HEC adapted to pH 8.3 and HEC-RM adapted to pH 7.3 exhibited the greatest verotoxin concentrations (2,470 and 1,460 ng/ml, respectively) at approximately 108 CFU/ml. In addition, the ratio of extracellular to intracellular verotoxin concentration decreased at acidic pH, possibly due to the decrease of membrane fluidity. These results suggest that while the rpoS gene does not influence acid resistance in acid-adapted cells it does confer decreased membrane fluidity, which may increase acid resistance and decrease verotoxin secretion.

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