The effects of nimodipine and L-NAME on coronary flow and oxidative stress parameters in isolated rat heart

2006 ◽  
Vol 93 (4) ◽  
pp. 251-261 ◽  
Author(s):  
VLj Jakovljevic ◽  
VLj Jakovljevic ◽  
PS Canovic ◽  
PS Canovic ◽  
PS Canovic ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Rat Heart ◽  
Coronary Flow ◽  
Isolated Rat Heart ◽  
Oxidative Stress Parameters ◽  
And Oxidative Stress ◽  
Stress Parameters ◽  
Isolated Rat

The effects of verapamil and its combinations with glutamate and glycine on cardiodynamics, coronary flow and oxidative stress in isolated rat heart

2016 ◽  
Vol 73 (1) ◽  
pp. 141-153 ◽  
Author(s):  
Isidora Stojic ◽  
Ivan Srejovic ◽  
Vladimir Zivkovic ◽  
Nevena Jeremic ◽  
Marko Djuric ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Rat Heart ◽  
Coronary Flow ◽  
Isolated Rat Heart ◽  
And Oxidative Stress ◽  
Isolated Rat

scholarly journals Effect of oleuropein on myocardial dysfunction and oxidative stress induced by ischemic-reperfusion injury in isolated rat heart

2016 ◽  
Vol 7 (4) ◽  
pp. 224-230 ◽  
Author(s):  
Mansour Esmailidehaj ◽  
Shirin Bajoovand ◽  
Mohammad Ebrahim Rezvani ◽  
Mozhdeh Sherifidehaj ◽  
Zahra Hafezimoghadam ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Reperfusion Injury ◽  
Rat Heart ◽  
Myocardial Dysfunction ◽  
Isolated Rat Heart ◽  
Ischemic Reperfusion Injury ◽  
Ischemic Reperfusion ◽  
And Oxidative Stress ◽  
Isolated Rat

scholarly journals Effects of DL-Homocysteine Thiolactone on Cardiac Contractility, Coronary Flow, and Oxidative Stress Markers in the Isolated Rat Heart: The Role of Different Gasotransmitters

2013 ◽  
Vol 2013 ◽  
pp. 1-9 ◽  
Author(s):  
Vladimir Zivkovic ◽  
Vladimir Jakovljevic ◽  
Olga Pechanova ◽  
Ivan Srejovic ◽  
Jovana Joksimovic ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Coronary Flow ◽  
Cardiac Contractility ◽  
Isolated Rat Heart ◽  
Oxidative Stress Markers ◽  
Homocysteine Thiolactone ◽  
Stress Markers ◽  
And Oxidative Stress ◽  
Isolated Rat

Considering the adverse effects of DL-homocysteine thiolactone hydrochloride (DL-Hcy TLHC) on vascular function and the possible role of oxidative stress in these mechanisms, the aim of this study was to assess the influence of DL-Hcy TLHC alone and in combination with specific inhibitors of important gasotransmitters, such as L-NAME, DL-PAG, and PPR IX, on cardiac contractility, coronary flow, and oxidative stress markers in an isolated rat heart. The hearts were retrogradely perfused according to the Langendorff technique at a 70 cm H2O and administered 10 μM DL-Hcy TLHC alone or in combination with 30 μM L-NAME, 10 μM DL-PAG, or 10 μM PPR IX. The following parameters were measured:dp/dtmax,dp/dtmin, SLVP, DLVP, MBP, HR, and CF. Oxidative stress markers were measured spectrophotometrically in coronary effluent through TBARS, NO2,O2-, and H2O2concentrations. The administration of DL-Hcy TLHC alone decreaseddp/dtmax, SLVP, and CF but did not change any oxidative stress parameters. DL-Hcy TLHC with L-NAME decreased CF,O2-, H2O2, and TBARS. The administration of DL-Hcy TLHC with DL-PAG significantly increaseddp/dtmax but decreased DLVP, CF, and TBARS. Administration of DL-Hcy TLHC with PPR IX caused a decrease indp/dtmax, SLVP, HR, CF, and TBARS.

The effects of the modulation of NMDA receptors by homocysteine thiolactone and dizocilpine on cardiodynamics and oxidative stress in isolated rat heart

2014 ◽  
Vol 401 (1-2) ◽  
pp. 97-105 ◽  
Author(s):  
Ivan Srejovic ◽  
Vladimir Jakovljevic ◽  
Vladimir Zivkovic ◽  
Nevena Barudzic ◽  
Ana Radovanovic ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Nmda Receptors ◽  
Rat Heart ◽  
Isolated Rat Heart ◽  
Homocysteine Thiolactone ◽  
And Oxidative Stress ◽  
Isolated Rat

Omega-3 fatty acids and mood stabilizers alter behavioral and oxidative stress parameters in animals subjected to fenproporex administration

2016 ◽  
Vol 32 (2) ◽  
pp. 519-528 ◽  
Author(s):  
Lara M. Gomes ◽  
Milena Carvalho-Silva ◽  
Letícia J. Teixeira ◽  
Joyce Rebelo ◽  
Isabella T. Mota ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Fatty Acids ◽  
Mood Stabilizers ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Oxidative Stress Parameters ◽  
And Oxidative Stress ◽  
Stress Parameters
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