Omega-3 fatty acids and mood stabilizers alter behavioral and oxidative stress parameters in animals subjected to fenproporex administration

2016 ◽  
Vol 32 (2) ◽  
pp. 519-528 ◽  
Author(s):  
Lara M. Gomes ◽  
Milena Carvalho-Silva ◽  
Letícia J. Teixeira ◽  
Joyce Rebelo ◽  
Isabella T. Mota ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Fatty Acids ◽  
Mood Stabilizers ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Oxidative Stress Parameters ◽  
And Oxidative Stress ◽  
Stress Parameters

Omega-3 fatty acids alter behavioral and oxidative stress parameters in animals subjected to fenproporex administration

2014 ◽  
Vol 29 (1) ◽  
pp. 185-192 ◽  
Author(s):  
Camila S. Model ◽  
Lara M. Gomes ◽  
Giselli Scaini ◽  
Gabriela K. Ferreira ◽  
Cinara L. Gonçalves ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Fatty Acids ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Oxidative Stress Parameters ◽  
And Oxidative Stress ◽  
Stress Parameters

Omega-3 fatty acids supplementation and oxidative stress parameters: A systematic review and meta-analysis of clinical trials

2019 ◽  
Vol 149 ◽  
pp. 104462 ◽  
Author(s):  
Javad Heshmati ◽  
Mojgan Morvaridzadeh ◽  
Saman Maroufizadeh ◽  
Abolfazl Akbari ◽  
Mahsa Yavari ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Systematic Review ◽  
Fatty Acids ◽  
Clinical Trials ◽  
Meta Analysis ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Oxidative Stress Parameters ◽  
And Oxidative Stress ◽  
Stress Parameters

scholarly journals Changes in Oxidative Stress Parameters as Response to Supplementation With Vitamin E and Omega-3 Fatty Acids in Male Workers Exposed to High Level Noise

2021 ◽  
Author(s):  
Hamzeh Mohammadi ◽  
Farideh Golbabaei ◽  
Somayeh Farhang Dehghan ◽  
Nariman Moradi ◽  
Maryam Chamari ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Fatty Acids ◽  
Vitamin E ◽  
Assay Method ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Decremental Effect ◽  
Oxidative Stress Parameters ◽  
Incremental Effect ◽  
Stress Parameters

Abstract Background: The present study aimed to assess the effects of the supplementation consumption of vitamin E and Omega 3 fatty acid on the oxidative stress parameters among workers exposed to high levels of noise in an automobile parts manufacturing plant. Moreover, the effects of the exposure to noise on SOD, total oxidative stress (TAC) and MDA will be investigated. Methods: The participants were deployed into 4 groups (vitamin E (100 mg), Omega 3 fatty acids (180 mg EPA and 120 mg DHA), vitamin E+ Omega 3 and Placebo), as per the double-blind block randomization method. The oxidative stress parameters of the participants were analyzed before and after three month consumption of supplements via enzyme-linked immunosorbent assay method. The level of workers' exposure to noise, was measured according to ISO 9612. Results: Before intervention, mean MDA, SOD and TAC were 27.52 (7.46) nmol/ml, 58.84 (10.44) U/ml and 2.57 (0.67) mM respectively. After intervention, mean MDA, SOD and TAC were 24.57 (7.58) nmol/ml, 63.46 (11.02) U/ml and 2.70 (0.84) mM respectively. The use of supplement Omega 3 fatty acids had a significant decremental effect on MDA levels. The use of vitamin E alongside Omega 3 fatty acids had a significant incremental effect on SOD activity.Conclusion: Noise exposure had a decremental effect on TAC and SOD as well as an incremental effect on MDA, but this was only statistically significant for TAC. It appears that the simultaneous use of vitamin E and Omega 3 fatty acids for three months had a positive effect on the anti-oxidant performance of workers exposed to noise.

scholarly journals Effect of omega-3 fatty acids supplementation on cardio-metabolic and oxidative stress parameters in patients with chronic kidney disease: a systematic review and meta-analysis

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Siavash Fazelian ◽  
Fatemeh Moradi ◽  
Shahram Agah ◽  
Akramsadat Hoseini ◽  
Hafez Heydari ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Systematic Review ◽  
Blood Pressure ◽  
Meta Analysis ◽  
Density Lipoprotein ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Oxidative Stress Parameters ◽  
And Oxidative Stress ◽  
Stress Parameters

Abstract Background Omega-3 fatty acids (FAs) have been suggested as a beneficial supplement in chronic kidney disease (CKD) patients, but the results of randomized clinical trials (RCTs) are controversial. We conducted a systematic review and meta-analysis to evaluate all the RCTs about the impact of omega-3 FAs supplementation on cardiometabolic outcomes and oxidative stress parameters in patients with CKD. Methods We performed a systematic database search in PubMed/MEDLINE, EMBASE, Scopus, Web of Science, and Cochrane Central, up to May 2020. We included all placebo-controlled randomized trials that assessed the effect of omega-3 FAs supplementation on any cardiometabolic outcomes: blood pressure, total cholesterol (TC), low-density lipoprotein (LDL) and high-density lipoprotein (HDL) or triglycerides (TG) and oxidative stress parameters. Data were pooled using DerSimonian–Laird’s random-effects model. Results Finally, thirteen articles met the inclusion criteria for this review omega-3 FAs supplementation significantly decrease TC (SMD: -0.26; 95% CI: − 0.51, − 0.02; I2 = 52.7%), TG (SMD: -0.22; 95% CI: − 0.43, − 0.02; I2 = 36.0%) and Malondialdehyde (MDA) levels (SMD: -0.91; 95% CI: − 1.29, − 0.54; I2 = 00.0%) and also significantly increase superoxide dismutase (SOD) (SMD: 0.58; 95% CI: 0.27, 0.90; I2 = 00.0%) and Glutathione peroxidase (GPx) (SMD: 0.50; 95% CI: 0.14, 0.86; I2 = 00.0%) activities. However our results show that omega-3 FAs supplementation have no significant effects on HDL, LDL and blood pressure. Conclusion This systematic review and meta-analysis supports current evidence for the clinical benefit of omega-3 FAs intake to improve cardiometabolic parameters in CKD patients. However, well-designed RCTs still needed to provide a conclusive picture in this field.

PP299 EFFECT OF ORAL SUPPLEMENTATION ENRICHED WITH OMEGA-3 FATTY ACIDS IN INFLAMATORY PARAMETERS AND OXIDATIVE STRESS IN PATIENTS WITH OTOLARYNGOLOGIST CANCER TREATED WITH RADIOTHERAPY

2010 ◽  
Vol 5 (2) ◽  
pp. 140 ◽  
Author(s):  
J.M. Garcia-Almeida ◽  
M. Murri-Pierri ◽  
Y. Lupiéñez ◽  
J.M. Rico-Pérez ◽  
H. Saracho-dominguez ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Fatty Acids ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Oral Supplementation ◽  
And Oxidative Stress

scholarly journals Effect of Vitamin E and Omega-3 Fatty Acids on Protecting Ambient PM2.5-Induced Inflammatory Response and Oxidative Stress in Vascular Endothelial Cells

PLoS ONE ◽  
2016 ◽  
Vol 11 (3) ◽  
pp. e0152216 ◽  
Author(s):  
Liang Bo ◽  
Shuo Jiang ◽  
Yuquan Xie ◽  
Haidong Kan ◽  
Weimin Song ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Fatty Acids ◽  
Endothelial Cells ◽  
Vitamin E ◽  
Inflammatory Response ◽  
Vascular Endothelial Cells ◽  
Vascular Endothelial ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
And Oxidative Stress

Proteomic analysis of aorta of LDLR−/−mice given omega-3 fatty acids reveals modulation of energy metabolism and oxidative stress pathway

2013 ◽  
Vol 115 (12) ◽  
pp. 1492-1498 ◽  
Author(s):  
Laurie Joumard-Cubizolles ◽  
Cécile Gladine ◽  
Nicolas Gérard ◽  
Christophe Chambon ◽  
Patrick Brachet ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Fatty Acids ◽  
Energy Metabolism ◽  
Proteomic Analysis ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Oxidative Stress Pathway ◽  
Stress Pathway ◽  
And Oxidative Stress

scholarly journals Decrease of Atherosclerosis Markers and Oxidative Stress After 1 Year Administration of Omega-3 Fatty Acids Supplements in Patients with Metabolic Syndrome

2014 ◽  
Vol 21 (3) ◽  
pp. 175-183
Author(s):  
Andreea Dragomir ◽  
Emila Rusu ◽  
Mihaela Posea ◽  
Gabriela Radulian
Keyword(s):  
Oxidative Stress ◽  
Metabolic Syndrome ◽  
Fatty Acids ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Atherosclerosis Progression ◽  
Group A ◽  
Group B ◽  
The Impact ◽  
And Oxidative Stress

AbstractBackground and Aims: To assess the impact of 1 year administration of omega-3 fatty acids supplements on oxidative stress parameters and atherosclerosis progression. Material and Methods: A total of 284 patients with metabolic syndrome, aged 61±6.7 years, without clinical evidence of atherosclerosis were allocated to 2 groups, matched by sex and age: group A (140 patients) - diet according to ESC/EASD recommendations; group B (144 patients) - the same diet + capsules of fish oil (1g eicosapentanoic acid, 1g docosahexanoic acid, 0,1g a-tocopherol acetate). Body fat (BF) was measured by bioimpedance analysis. For oxidative stress evaluation we used the FormOx systems monitor on a blood drop and for progression of atherosclerosis the intima-media thickness (IMT) at common carotid artery. Patients were evaluated at baseline, after 6 months and 1 year. Results: IMT significantly decreased in group B vs group A at 1 year (p<0.0001) and was correlated with %BF (p<0.001), waist-to-hip ratio (WHR) (p=0.002), leptin (p< 0.001), adiponectin (p<0.05), leptin/adiponectin ratio (p< 0.001) and oxidative stress (p<0.001). Conclusions: One year administrations of omega-3 PUFA enriched diet reduces cardiovascular risk of metabolic syndrome patients, resulting in a significant decrease of oxidative stress and atherosclerosis progression.

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