Oxygen diffusivities in mullite/zirconia composites measured by 18O/16O isotope exchange and secondary ion mass spectrometry

2008 ◽  
Vol 23 (2) ◽  
pp. 353-358 ◽  
Author(s):  
Hong-Da Ko ◽  
Chien-Cheng Lin
Keyword(s):  
Mass Spectrometry ◽  
Isotope Exchange ◽  
Secondary Ion Mass Spectrometry ◽  
Fixed Temperature ◽  
Wide Range ◽  
Zirconia Composites ◽  
Ion Mass Spectrometry ◽  
O Isotope ◽  
Secondary Ion ◽  
Range Of Values

Oxygen diffusivities in mullite/zirconia composites were measured by 18O/16O isotope exchange and secondary ion mass spectrometry. They exhibited a wide range of values from 10−21 to 10−10 m2/s at temperatures between 1000 and 1350 °C in the composites with 0 to 80 vol% zirconia. At a fixed temperature, oxygen diffusivities in high-zirconia composites were larger by at least eight orders of magnitude than those in low-zirconia composites. The percolation threshold occurred between 30 and 40 vol% zirconia, where oxygen diffusivities dramatically changed. There was a clear tendency of the activation energies of oxygen diffusion in composites to decrease with increasing zirconia contents. The large oxygen diffusivities in the high-zirconia composites were attributed to the interconnected channels of zirconia from the microstructural aspect.

A novel sample preparation method for ultra-high vacuum (UHV) secondary ion mass spectrometry (SIMS) analysis

2018 ◽  
Vol 33 (9) ◽  
pp. 1559-1563 ◽  
Author(s):  
Wanfeng Zhang ◽  
Xiaoping Xia ◽  
Yanqiang Zhang ◽  
Touping Peng ◽  
Qing Yang
Keyword(s):  
Mass Spectrometry ◽  
Secondary Ion Mass Spectrometry ◽  
Earth Science ◽  
High Vacuum ◽  
High Sensitivity ◽  
Science Research ◽  
Ultra High Vacuum ◽  
Wide Range ◽  
Ion Mass Spectrometry ◽  
Secondary Ion

Secondary ion mass spectrometry (SIMS) has been applied to analyze a wide range of materials for earth science research due to its high sensitivity, high precision and capacity for in situ micro-analysis.

scholarly journals SIMS (Imaging Secondary Ion Mass Spectrometry) Analysis of a Cross-section Sample From Leonardo Da Vinci’s Adoration of the Magi

2020 ◽  
Author(s):  
Hua Tian ◽  
Maurizio Seracini ◽  
Katherine Schimmel ◽  
Stephen J. Benkovic ◽  
Nicholas Winograd
Keyword(s):  
Mass Spectrometry ◽  
Cross Section ◽  
Secondary Ion Mass Spectrometry ◽  
Ion Source ◽  
Mass Spectrometry Analysis ◽  
Sequence Of Events ◽  
Wide Range ◽  
Ion Mass Spectrometry ◽  
Chloride Salts ◽  
Secondary Ion

Abstract Paintings often consist of highly complex layered structures that contain a mixture of organic and inorganic materials at each layer depending upon the artist’s technique. A comprehensive analysis of the chemical composition could provide critical information on the sequence of events that led to an artwork’s current state. In this investigation, we have employed a novel imaging technique known as Secondary Ion Mass Spectrometry (SIMS) to chemically map the cross-section of a paint film sampled from Leonardo da Vinci’s Adoration of the Magi at a submicron resolution using a C60+ ion source. A wide range of materials were found to be spatially localized at the different layers such as: protein, carbon, silicates, fatty acids, salts and lead associated compounds. An interaction of chloride salts with the lead white was observed in the priming layer. The chloride salts disrupted most of the priming layer suggesting that a cleaning process took place that removed most of the priming layer before the monochrome brown repaints were added on top at a later time.

Applications of Time-OF-Flight Secondary Ion Mass Spectrometry (TOF-SIMS)

1990 ◽  
Vol 48 (2) ◽  
pp. 308-309
Author(s):  
Bruno Schueler ◽  
Robert W. Odom
Keyword(s):  
Mass Spectrometry ◽  
Secondary Ion Mass Spectrometry ◽  
Structural Information ◽  
Time Of Flight ◽  
Biological Tissues ◽  
Polymer Surfaces ◽  
Tof Sims ◽  
Secondary Ions ◽  
Ion Mass Spectrometry ◽  
Secondary Ion

Time-of-flight secondary ion mass spectrometry (TOF-SIMS) provides unique capabilities for elemental and molecular compositional analysis of a wide variety of surfaces. This relatively new technique is finding increasing applications in analyses concerned with determining the chemical composition of various polymer surfaces, identifying the composition of organic and inorganic residues on surfaces and the localization of molecular or structurally significant secondary ions signals from biological tissues. TOF-SIMS analyses are typically performed under low primary ion dose (static SIMS) conditions and hence the secondary ions formed often contain significant structural information.This paper will present an overview of current TOF-SIMS instrumentation with particular emphasis on the stigmatic imaging ion microscope developed in the authors’ laboratory. This discussion will be followed by a presentation of several useful applications of the technique for the characterization of polymer surfaces and biological tissues specimens. Particular attention in these applications will focus on how the analytical problem impacts the performance requirements of the mass spectrometer and vice-versa.

Optics-Free Visualization of Proteins in Single Cells by Time of Flight-Secondary Ion Mass Spectrometry Coupled with Genetically Encoded Chemical Tags

2020 ◽  
Author(s):  
Feifei Jia ◽  
Jie Wang ◽  
Yanyan Zhang ◽  
Qun Luo ◽  
Luyu Qi ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Secondary Ion Mass Spectrometry ◽  
Single Cells ◽  
Time Of Flight ◽  
E Coli ◽  
Tof Sims ◽  
Ion Mass Spectrometry ◽  
Chemical Tags ◽  
Secondary Ion

<p></p><p><i>In situ</i> visualization of proteins of interest at single cell level is attractive in cell biology, molecular biology and biomedicine, which usually involves photon, electron or X-ray based imaging methods. Herein, we report an optics-free strategy that images a specific protein in single cells by time of flight-secondary ion mass spectrometry (ToF-SIMS) following genetic incorporation of fluorine-containing unnatural amino acids as a chemical tag into the protein via genetic code expansion technique. The method was developed and validated by imaging GFP in E. coli and human HeLa cancer cells, and then utilized to visualize the distribution of chemotaxis protein CheA in E. coli cells and the interaction between high mobility group box 1 protein and cisplatin damaged DNA in HeLa cells. The present work highlights the power of ToF-SIMS imaging combined with genetically encoded chemical tags for <i>in situ </i>visualization of proteins of interest as well as the interactions between proteins and drugs or drug damaged DNA in single cells.</p><p></p>

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