The effectiveness of tubal infertility treatment in ART programs depending on ovarian stimulation protocol

The objective: of the investigation was to study the effectiveness of treatment of women with tubal infertility, depending on the protocol of ovarian stimulation. Materials and methods. To achieve tht goal, the medical documentation of patients who contacted the «Mother and Child» Medical Center in 2012-2013 was analyzed. To compare the efficacy of different ovarian stimulation protocols were selected 387 patients under the age of 35 years with tubal infertility, who were stimulated by standard protocols with further separation into two groups: S (short stimulation protocol, n=246) and L (long stimulation protocol, n=141). In both groups, an intracytoplasmic sperm injection (ICSI) was performed. Results.The mean duration of stimulation in a long protocol was on 2 days longer. The total amount of spent rFSH was also significantly (by 300 IU) more. There was no significant difference between the number of blastocysts and high quality blastocysts. The cumulative efficacy of treatment after 1 year was 82.33% and 77.30% (p>0.05). Conclusion. The retrospective study showed that women with tubal infertility in a long protocol require a longer stimulation, using a larger total dose of recombinant FSH, with the same end-point effectiveness. Key words: tubal peritoneal infertility, in vitro fertilization, stimulation of superovulation, treatment effectiveness.