scholarly journals Announcement: Final 2015–16 Influenza Vaccination Coverage Estimates for Selected Local Areas, States, and the United States Available Online

2016 ◽  
Vol 65 (38) ◽  
pp. 1041
Keyword(s):  
United States ◽  
Influenza Vaccination ◽  
Vaccination Coverage ◽  
The United States ◽  
Local Areas

scholarly journals The Impact of Influenza Vaccination on Antibiotic Use in the United States, 2010–2017

2020 ◽  
Vol 7 (7) ◽  
Author(s):  
Eili Y Klein ◽  
Emily Schueller ◽  
Katie K Tseng ◽  
Daniel J Morgan ◽  
Ramanan Laxminarayan ◽  
...  
Keyword(s):  
United States ◽  
Influenza Vaccination ◽  
Vaccination Coverage ◽  
State Level ◽  
Population Level ◽  
Antibiotic Use ◽  
The United States ◽  
Vaccine Effectiveness ◽  
Severe Illness ◽  
Antibiotic Prescribing

Abstract Background Influenza, which peaks seasonally, is an important driver for antibiotic prescribing. Although influenza vaccination has been shown to reduce severe illness, evidence of the population-level effects of vaccination coverage on rates of antibiotic prescribing in the United States is lacking. Methods We conducted a retrospective analysis of influenza vaccination coverage and antibiotic prescribing rates from 2010 to 2017 across states in the United States, controlling for differences in health infrastructure and yearly vaccine effectiveness. Using data from IQVIA’s Xponent database and the US Centers for Disease Control and Prevention’s FluVaxView, we employed fixed-effects regression analysis to analyze the relationship between influenza vaccine coverage rates and the number of antibiotic prescriptions per 1000 residents from January to March of each year. Results We observed that, controlling for socioeconomic differences, access to health care, childcare centers, climate, vaccine effectiveness, and state-level differences, a 10–percentage point increase in the influenza vaccination rate was associated with a 6.5% decrease in antibiotic use, equivalent to 14.2 (95% CI, 6.0–22.4; P = .001) fewer antibiotic prescriptions per 1000 individuals. Increased vaccination coverage reduced prescribing rates the most in the pediatric population (0–18 years), by 15.2 (95% CI, 9.0–21.3; P < .001) or 6.0%, and the elderly (aged 65+), by 12.8 (95% CI, 6.5–19.2; P < .001) or 5.2%. Conclusions Increased influenza vaccination uptake at the population level is associated with state-level reductions in antibiotic use. Expanding influenza vaccination could be an important intervention to reduce unnecessary antibiotic prescribing.

scholarly journals Seasonal Influenza Vaccination Coverage Among Adult Populations in the United States, 2005-2011

2013 ◽  
Vol 178 (9) ◽  
pp. 1478-1487 ◽  
Author(s):  
P.-J. Lu ◽  
J. A. Singleton ◽  
G. L. Euler ◽  
W. W. Williams ◽  
C. B. Bridges
Keyword(s):  
United States ◽  
Influenza Vaccination ◽  
Vaccination Coverage ◽  
Seasonal Influenza ◽  
The United States ◽  
Seasonal Influenza Vaccination

scholarly journals 2742. The Impact of Influenza Vaccination on Antibiotic Use in the United States, 2010–2017

2019 ◽  
Vol 6 (Supplement_2) ◽  
pp. S965-S966
Author(s):  
Eili Klein ◽  
Emily Schueller ◽  
Katie K Tseng ◽  
Arindam Nandi
Keyword(s):  
United States ◽  
Antibiotic Resistance ◽  
Influenza Vaccination ◽  
Vaccination Coverage ◽  
Seasonal Influenza ◽  
Antibiotic Use ◽  
The United States ◽  
Antibiotic Prescribing ◽  
Coverage Rates ◽  
The Impact

Abstract Background Antibiotic resistance is a cause of morbidity and mortality driven by inappropriate prescribing. In the United States, a third of all outpatient antibiotic prescriptions may be inappropriate. Seasonal influenza rates are significantly associated with antibiotic prescribing rates. The impact of influenza vaccination coverage on antibiotic prescribing is unknown. Methods We conducted a retrospective analysis of state-level vaccination coverage and antibiotic prescribing rates from 2010 to 2017. We used fixed effects regression to analyze the relationship between cumulative vaccine coverage rates for a season and the per capita number of prescriptions for systemic antibiotics for the corresponding season (January–March) controlling for temperature, poverty, healthcare infrastructure, population structure, and vaccine effectiveness. Results Rates of vaccination coverage ranged from 33% in Nevada to 52% in Rhode Island for the 2016–2017 season, while antibiotic use rates ranged from 25 prescriptions per 1,000 inhabitants in Alaska to 377 prescriptions per 1,000 inhabitants in West Virginia (Figure 1). Vaccination coverage rates were highly correlated with reduced prescribing rates, and controlling for other factors, we found that a one percent increase in the influenza vaccination rate was associated with 1.40 (95% CI: 2.22–0.57, P < 0.01) fewer antibiotic prescriptions per 1,000 inhabitants (Table 1). Increases in the vaccination coverage rate in the pediatric population (aged 0–18) had the strongest effect, followed by the elderly (aged 65+). Conclusion Vaccination can reduce morbidity and mortality from seasonal influenza. Though coverage rates are far below levels necessary to generate herd immunity, we found that higher coverage rates in a state were associated with lower antibiotic prescribing rates. While the effectiveness of the vaccine varies from year to year and the factors that drive antibiotic prescribing rates are multi-factorial, these results suggest that increased vaccination coverage for influenza would have significant benefit in terms of reducing antibiotic overuse and correspondingly antibiotic resistance. Disclosures All authors: No reported disclosures.

scholarly journals Monitoring seasonal influenza vaccination coverage among pregnant women in the United States

2012 ◽  
Vol 207 (3) ◽  
pp. S9-S16 ◽  
Author(s):  
Erin D. Kennedy ◽  
Indu B. Ahluwalia ◽  
Helen Ding ◽  
Peng-Jun Lu ◽  
James A. Singleton ◽  
...  
Keyword(s):  
United States ◽  
Influenza Vaccination ◽  
Pregnant Women ◽  
Vaccination Coverage ◽  
Seasonal Influenza ◽  
The United States ◽  
Seasonal Influenza Vaccination

scholarly journals Trends in Childhood Influenza Vaccination Coverage, United States, 2012-2019

2020 ◽  
Vol 135 (5) ◽  
pp. 640-649
Author(s):  
Tammy A. Santibanez ◽  
Anup Srivastav ◽  
Yusheng Zhai ◽  
James A. Singleton
Keyword(s):  
United States ◽  
Influenza Vaccination ◽  
Vaccination Coverage ◽  
Age Groups ◽  
The United States ◽  
Health Conditions ◽  
Kaplan Meier ◽  
National Immunization ◽  
Previous Season ◽  
Increased Risk

Objective The objective was to compare estimates of childhood influenza vaccination across 7 consecutive influenza seasons based on 2 survey systems. Methods We analyzed data from the National Health Interview Survey (NHIS) and the National Immunization Survey–Flu (NIS-Flu) using Kaplan-Meier survival analysis to estimate receipt, based on parental report, of at least 1 dose of influenza vaccine among children aged 6 months to 17 years. Results We found no significant increasing trend in influenza vaccination coverage among children overall from 2012 to 2018 based on the NHIS or from 2012 to 2019 based on the NIS-Flu. We found 4 seasons with a significant increase in influenza vaccination coverage compared with the previous season (2012-2013 [NHIS, NIS-Flu], 2013-2014 [NIS-Flu], 2017-2018 [NHIS], and 2018-2019 [NIS-Flu]). As of the 2018-2019 season, based on NIS-Flu, influenza vaccination coverage was only 62.6%. Children with health conditions that put them at increased risk for complications from influenza had higher influenza vaccination coverage than children without these health conditions for all the seasons studied except 2014-2015. For all seasons studied, influenza vaccination coverage estimates for children were higher based on NIS-Flu data compared with NHIS data. Trends across seasons and differences in vaccination coverage between age groups were similar between the 2 surveys. Conclusions Influenza vaccination coverage among children appears to have plateaued. Only about half of the children in the United States were vaccinated against influenza. Improvements in measurement of influenza vaccination and development and review of strategies to increase childhood influenza vaccination coverage are needed.

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