Removal Torque Analysis of Implants in Rabbit Tibia After Topical Application of Simvastatin Gel

2014 ◽  
Vol 40 (1) ◽  
pp. 53-59 ◽  
Author(s):  
Fatima Neves Faraco-Schwed ◽  
Luiz Macedo Mangueira ◽  
Joao Vitor Albuquerque Ribeiro ◽  
Alexsandro Da Silva Antao ◽  
Jamil Awad Shibli
Keyword(s):  
Topical Application ◽  
Topical Administration ◽  
Titanium Implants ◽  
Removal Torque ◽  
Implant Placement ◽  
Group I ◽  
Torque Wrench ◽  
Rabbit Tibia ◽  
Torque Analysis ◽  
Torque Values

The aim of this study was to evaluate the effects of topical application of simvastatin gel (7.5 mg) on the removal torque of titanium implants in the rabbit tibia. A total of 32 surgeries were performed on 16 New Zealand rabbits for the placement of 2 implants in 1 tibia of each rabbit. Only 1 of the surgical defects was injected with 30 mg/mL of simvastatin gel before implant placement. The initial torque was set at 20 N.cm, and removal torque testing was performed 28 and 56 days postoperatively with a Tonishi torque wrench. Surgical defects were divided into 4 groups: group IG-28 (test, 28 days), group IG-56 (test, 56 days), group I-28 (control, 28 days), and group I-56 (control, 56 days). Removal torque values were higher in group IG-56 than in groups IG-28, I-28, and I-56 (P < .05). Groups IG-28, I-28, and I-56 showed similar values (P > .05). Removal torque force increased under the influence of simvastatin, indicating that topical administration of a 7.5-mg dose of simvastatin gel is effective in improving the torque force required to remove implants inserted in the rabbit tibia.

scholarly journals Torque Analysis of a Triple Acid-Etched Titanium Implant Surface

2015 ◽  
Vol 2015 ◽  
pp. 1-3 ◽  
Author(s):  
Ana Emília Farias Pontes ◽  
Cássio Torres de Toledo ◽  
Valdir Gouveia Garcia ◽  
Fernando Salimon Ribeiro ◽  
Celso Eduardo Sakakura
Keyword(s):  
Titanium Implant ◽  
Titanium Implants ◽  
Acid Etching ◽  
Subtraction Method ◽  
Implant Surface ◽  
Removal Torque ◽  
Torque Analysis ◽  
Preliminary Study ◽  
Torque Values ◽  
Titanium Implant Surface

The present study aimed to evaluate the removal torque of titanium implants treated with triple acid etching. Twenty-one rats were used in this study. For all animals, the tibia was prepared with a 2 mm drill, and a titanium implant (2 × 4 mm) was inserted after treatment using the subtraction method of triple acid etching. The flaps were sutured. Seven animals were killed 14, 28, and 63 days after implant installation, and the load necessary for removing the implant from the bone was evaluated by using a torque meter. The torque values were as follows: 3.3 ± 1.7 Ncm (14 days), 2.2 ± 1.3 Ncm (28 days), and 6.7 ± 1.4 Ncm (63 days). The torque value at the final healing period (63 days) was statistically significantly different from that at other time points tested (ANOVA,p=0.0002). This preliminary study revealed that treatment with triple acid etching can create a promising and efficient surface for the process of osseointegration.

scholarly journals Histologic evaluation and removal torque analysis of nano- and microtreated titanium implants in the dogs

2009 ◽  
Vol 1 (2) ◽  
pp. 75 ◽  
Author(s):  
Seok Ahn ◽  
Mong-Sook Vang ◽  
Hong-So Yang ◽  
Sang-Won Park ◽  
Hyun-Pil Lim
Keyword(s):  
Titanium Implants ◽  
Removal Torque ◽  
Histologic Evaluation ◽  
Torque Analysis

scholarly journals Effect of Cyclic Precalcification of Nanotubular TiO2Layer on the Bioactivity of Titanium Implant

2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Il Song Park ◽  
Eun Jin Yang ◽  
Tae Sung Bae
Keyword(s):  
Titanium Implant ◽  
Treatment Method ◽  
Titanium Implants ◽  
Effective Surface ◽  
Removal Torque ◽  
Self Organized ◽  
Bioactive Properties ◽  
Activation Level ◽  
Anodized Titanium ◽  
Torque Values

The objective of this study is to investigate the effect of cyclic precalcification treatment to impart bioactive properties for titanium implants. Before precalcification, the titanium implants were subjected to blasting using hydroxyapatite (HAp), a resorbable blasting medium (RBM treated), and anodized using an electrolyte containing glycerol, H2O, and NH4F. Precalcification treatment was performed by two different methods, namely, continuous immersion treatment (CIT) and alternate immersion treatment (AIT). In CIT, the RBM treated and anodized titanium implants were immersed in 0.05 M NaH2PO4solution at 80°C and saturated Ca(OH)2solution at 100°C for 20 min, whereas during AIT, they were immersed alternatively in both solutions for 1 min for 20 cycles. Anodizing of the titanium implants enables the formation of self-organized TiO2nanotubes. Cyclic precalcification treatment imparts a better bioactive property and enables an increase in activation level of the titanium implants. The removal torque values of the RBM treated, CIT treated, and AIT treated titanium implants are10.8±3.7 Ncm,17.5±3.5 Ncm, and28.1±2.4 Ncm, respectively. The findings of the study indicate the cyclic precalcification in an effective surface treatment method that would help accelerate osseointegration and impart bioactive property of titanium implants.

The effect of strontium-loaded rough titanium surface on early osseointegration

2017 ◽  
Vol 32 (5) ◽  
pp. 561-569 ◽  
Author(s):  
Jiang Huanhuan ◽  
Hao Pengjie ◽  
Xu Sheng ◽  
Wang Binchen ◽  
Shu Li
Keyword(s):  
Magnetron Sputtering ◽  
Titanium Implant ◽  
Surface Characteristics ◽  
Atomic Ratio ◽  
Area Ratio ◽  
Titanium Implants ◽  
Bone Area ◽  
Bone Apposition ◽  
Removal Torque ◽  
Torque Values

It is not clear whether surface bioactive chemistry plays an important role in the early osseointegration of micro-structured titanium implants that have the same surface topography at the micrometer and submicrometer scales. In this study, magnetron sputtering methodology was employed for the preparation of Sr coating on sandblasted and acid-etched (SLA) titanium implant without changing the surface characteristics. The study of the surface morphology of the coating was carried out with the use of scanning electron microscopy, and the chemical composition of the surface was examined by X-ray energy-dispersive spectrometry. Twenty SLA implants together with 20 Sr-SLA implants were randomly inserted into the proximal tibia of 20 rats. The early osseointegration of the Sr-SLA implant was compared with SLA implant by removal torque test and histological analysis following two and eight weeks of implantation, correspondingly. As revealed by the surface characteristics, both Sr-SLA and SLA surfaces exhibited similar typical isotropic irregular indentations. The strontium ions were effectively incorporated into the SLA surface (the atomic ratio is 2%). Following two and eight weeks of healing, significant increases in removal torque values ( p < 0.05) were taken into observation in respect of Sr-SLA implant. Histologically, the Sr-SLA implants displayed significantly higher bone-to-implant contact percentages and bone area ratio in comparison with the SLA implant at eight weeks ( p < 0.05). At two weeks, the bone-implant contact percentages, together with bone area ratio of Sr-SLA surface appeared to be a little bit slightly greater than that of SLA surface. But the statistical difference was not significant. These results indicated that the chemical modification with Sr incorporated by magnetron sputtering treatment in moderately rough surfaced implants remarkably increases early bone apposition.

Effect of Systemic Intermittent Administration of Human Parathyroid Hormone (RHPTH[1–34]) on the Resistance to Reverse Torque in Rabbit Tibiae

2008 ◽  
Vol 34 (6) ◽  
pp. 298-302 ◽  
Author(s):  
Marcelo Soeiro Corsini ◽  
Fátima N. Faraco ◽  
Alessandra A. Pereira Castro ◽  
Tatiana Onuma ◽  
Wilson R. Sendyk ◽  
...  
Keyword(s):  
Parathyroid Hormone ◽  
Test Group ◽  
Control Group ◽  
Human Parathyroid Hormone ◽  
Removal Torque ◽  
Intermittent Administration ◽  
Reverse Torque ◽  
Implant Placement ◽  
Torque Values ◽  
The Right

Abstract The aim of this study was to evaluate the effect of intermittent administration of human parathyroid hormone [rhPTH (1–34)] on the removal torque of implants placed in rabbit tibiae. Twenty male New Zealand rabbits were submitted to implant surgery. Each animal received one machined screw-type implant (3.75 mm diameter × 8 mm length) in the proximal metaphysis of the right tibia. The rabbits were then divided into 2 groups: the test group (n = 10) received 6 μg/kg of rhPTH (1–34) subcutaneously in the dorsal region 3 days a week, and the control group (n = 10) received placebo. Removal torque was performed at 28 and 56 days after implant placement for both groups. The mean removal torque values at 28 days were 37.0 ± 4.36 Ncm and 47.4 ± 6.77 Ncm for control and test groups respectively (P &lt; .05). At 56 days the reverse torque was 45.8 ± 3.96 Ncm for the control group and 55.8 ± 2.86 Ncm for the test group, indicating that the removal torque was significantly higher in the test groups (P &lt; .05). These results demonstrated that intermittent treatment with rhPTH (1–34) enhanced the removal torque of implants in rabbit tibiae.

Histomorphometric and removal torque analysis for TiO2 hyphen;blasted titanium implants. An experimental study on dogs.

1992 ◽  
Vol 3 (2) ◽  
pp. 77-84 ◽  
Author(s):  
Klaus Gotfredsen ◽  
Lars Nimb ◽  
Erik Hjörting-hansen ◽  
Jørgen Steen Jensen ◽  
Anders Holmén
Keyword(s):  
Experimental Study ◽  
Titanium Implants ◽  
Removal Torque ◽  
Torque Analysis
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