Implant site preparation application of injectable platelet-rich fibrin for vertical and horizontal bone regeneration: A clinical report

2020 ◽  
Author(s):  
Prakan Thanasrisuebwong ◽  
Sirichai Kiattavorncharoen ◽  
George R Deeb ◽  
Sompop Bencharit
Keyword(s):  
Bone Graft ◽  
Bone Regeneration ◽  
Bone Defect ◽  
Alveolar Bone ◽  
Treatment Protocol ◽  
Biologically Active ◽  
Asian Woman ◽  
Clinical Report ◽  
Platelet Rich Fibrin ◽  
Implant Placement

Guided bone regeneration (GBR) using a combined injectable platelet-rich fibrin (i-PRF), leukocyte- and platelet-rich fibrin (L-PRF) and biocompatible bone substitute materials, is a convenient and effective method to augment a combined vertical and horizontal bone defect. This approach can create sufficient bone quality and quantity for implant surgical sites. A 55-year-old Asian woman presented with a severe bone defect in posterior mandible. The edentulous mandibular alveolar ridge was severely resorbed vertically and horizontally.  A GBR procedure using i-PRF and L-PRF combined with particulate bone graft was performed. Postoperative cone beam computed tomography scans, 8 months after the augmentation, revealed a large regeneration of the alveolar bone sufficient for implant placement. A combination i-PRF/L-PRF and particulate bone graft may provide biologically active molecules as well as a scaffold for osteogenesis. This treatment protocol may be a viable option for a large bone defect required augmentation prior to implant placement.

scholarly journals Leucocyte- and Platelet-Rich Fibrin Block: Its Use for the Treatment of a Large Cyst with Implant-Based Rehabilitation

Medicina ◽  
2021 ◽  
Vol 57 (2) ◽  
pp. 180 ◽  
Author(s):  
Rodolfo Mauceri ◽  
Denise Murgia ◽  
Orazio Cicero ◽  
Luigi Paternò ◽  
Luca Fiorillo ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Bone Defect ◽  
Bone Healing ◽  
Bone Substitute ◽  
Alveolar Bone ◽  
Critical Size ◽  
Large Bone ◽  
Alveolar Bone Defect ◽  
Positive Results ◽  
Autologous Platelet

The management of critical-size bone defects is still demanding. Recently, autologous platelet concentrates in combination with bone substitute have been applied and reported in a few studies. Our aim is to report the healing of a critical-size alveolar bone defect treated with a new bone regeneration technique by means of L-PRF and L-PRF blocks. A 45-year-old woman presented a large cystic lesion; the extraction of three teeth, a cyst removal procedure, and bone regeneration procedures with L-PRF and L-PRF blocks were planned. The L-PRF block was prepared by mixing a bone substitute with a piece of L-PRF membrane and liquid fibrinogen. Additionally, after bone healing an implant-based rehabilitation was optimally performed. On the basis of the positive results, in terms of bone healing and tissue regeneration in a large bone defect, the application of L-PRF and L-PRF blocks, in agreement with the scarce literature, is suggested as a feasible procedure in selected cases.

A Novel Approach to Restore a Decayed Mandibular Posterior Tooth by Immediate Implant Placement Using Autogenous Tooth Graft Material Mixed with Platelet-Rich Fibrin: A Case Report

2021 ◽  
Author(s):  
Amit Khunger
Keyword(s):  
Case Report ◽  
Bone Graft ◽  
Graft Material ◽  
Present Case Report ◽  
Platelet Rich Fibrin ◽  
Implant Placement ◽  
Novel Approach ◽  
Decayed Tooth ◽  
Immediate Implant ◽  
Missing Tooth

A dental implant is the most accepted treatment option to replace the badly decayed tooth or missing tooth. The jumping gap left after the placement of the implant in the socket will require augmentation of bone graft material. In this case report, the extracted root stumps are used as an autogenous tooth graft material after its preparation. And PRF is mixed with graft material for additive advantage. So, the present case report discusses the feasibility of the use of autogenous tooth graft material along with PRF for the better osseointegration of the implant.

scholarly journals Bone Regeneration Using a Three-Dimensional Hexahedron Channeled BCP Block Combined with Bone Morphogenic Protein-2 in Rat Calvarial Defects

Materials ◽  
2019 ◽  
Vol 12 (15) ◽  
pp. 2435 ◽  
Author(s):  
So-Yeun Kim ◽  
Eun-Bin Bae ◽  
Jae-Woong Huh ◽  
Jong-Ju Ahn ◽  
Hyun-Young Bae ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Alveolar Bone ◽  
Three Dimensional ◽  
Bone Morphogenetic Protein 2 ◽  
Graft Material ◽  
Implant Placement ◽  
Morphogenetic Protein ◽  
Human Bone Morphogenetic Protein ◽  
Calvarial Defects ◽  
Rat Calvarial Defect

It is important to obtain sufficient bone mass before implant placement on alveolar bone, and synthetic bone such as biphasic calcium phosphate (BCP) has been studied to secure this. This study used a BCP block bone with a specific structure of the three-dimensional (3D) hexahedron channel and coating with recombinant human bone morphogenetic protein-2 (rhBMP-2) impregnated carboxymethyl cellulose (CMC) was used to examine the enhancement of bone regeneration of this biomaterial in rat calvarial defect. After the preparation of critical-size calvarial defects in fifteen rats, defects were divided into three groups and were implanted with the assigned specimen (n = 5): Boneplant (untreated 3D hexahedron channeled BCP block), Boneplant/CMC (3D hexahedron channeled BCP block coated with CMC), and Boneplant/CMC/BMP (3D hexahedron channeled BCP block coated with CMC containing rhBMP-2). After 4 weeks, the volumetric, histologic, and histometric analyses were conducted to measure the newly formed bone. Histologically, defects in the Boneplant/CMC/BMP group were almost completely filled with new bone compared to the Boneplant and Boneplant/CMC groups. The new bone volume (P < 0.05) and area (P < 0.001) in the Boneplant/CMC/BMP group (20.12% ± 2.17, 33.79% ± 3.66) were much greater than those in the Boneplant (10.77% ± 4.8, 16.48% ± 9.11) and Boneplant/CMC (10.72% ± 3.29, 16.57% ± 8.94) groups, respectively. In conclusion, the 3D hexahedron channeled BCP block adapted rhBMP-2 with carrier CMC showed high possibility as an effective bone graft material.

scholarly journals Alveolar Bone Regeneration for Immediate Implant Placement Using an Injectable Bone Substitute: An Experimental Study in Dogs

2004 ◽  
Vol 75 (5) ◽  
pp. 663-671 ◽  
Author(s):  
Damien Boix ◽  
Olivier Gauthier ◽  
Jérôme Guicheux ◽  
Paul Pilet ◽  
Pierre Weiss ◽  
...  
Keyword(s):  
Experimental Study ◽  
Bone Regeneration ◽  
Bone Substitute ◽  
Alveolar Bone ◽  
Implant Placement ◽  
Immediate Implant

Simultaneous Implant Placement and Guided Bone Regeneration Using a Platelet-Rich Fibrin Membrane: Case Report

2017 ◽  
Vol 7 (1) ◽  
pp. 19-24
Author(s):  
Yung-Ting Hsu ◽  
Yu-Hsiang Chou ◽  
Tzu-Hsuan Yang ◽  
Yi-Min Wu ◽  
Chiung-Lin Huang ◽  
...  
Keyword(s):  
Case Report ◽  
Bone Regeneration ◽  
Guided Bone Regeneration ◽  
Platelet Rich Fibrin ◽  
Implant Placement ◽  
Fibrin Membrane

scholarly journals Preservation or reconstruction of the Peri-implant bone- A Review

2021 ◽  
Vol 5 (3) ◽  
pp. 144-146
Author(s):  
Shamila Shetty K ◽  
◽  
R.K Nishith ◽  
R.K Nishith ◽  
Misha Rose Mathew ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Dental Implant ◽  
Alveolar Bone ◽  
Alveolar Ridge ◽  
Missing Teeth ◽  
Implant Placement ◽  
Biophysical Process ◽  
Implant Therapy ◽  
Teeth Extraction

The main biological and biophysical process that has made dental implant therapy predictably successful for replacing missing teeth is Osseointegration. Teeth extraction is done for several purposes, often without any consideration for the preservation of the alveolar ridge. Alveolar bone post-extraction changes have been estimated to cause a 50% decrease in alveolar bone buccolingual width, and a further loss in height. This review will go through various techniques of ARP and bone regeneration techniques and explore the best way to obtain the best outcomes after implant placement.

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