Detection of Abnormal Features in Digital Fundus Image Using Morphological Approach for Classification of Diabetic Retinopathy

Author(s):  
Aniruddha L. Pal, Dr .Srikanth Prabhu
Author(s):  
Alfiya Md. Shaikh

Abstract: Diabetic retinopathy (DR) is a medical condition that damages eye retinal tissues. Diabetic retinopathy leads to mild to complete blindness. It has been a leading cause of global blindness. The identification and categorization of DR take place through the segmentation of parts of the fundus image or the examination of the fundus image for the incidence of exudates, lesions, microaneurysms, and so on. This research aims to study and summarize various recent proposed techniques applied to automate the process of classification of diabetic retinopathy. In the current study, the researchers focused on the concept of classifying the DR fundus images based on their severity level. Emphasis is on studying papers that proposed models developed using transfer learning. Thus, it becomes vital to develop an automatic diagnosis system to support physicians in their work.


2014 ◽  
Vol 22 (03) ◽  
pp. 413-428 ◽  
Author(s):  
M. PONNIBALA ◽  
S. VIJAYACHITRA

One of the greatest concerns to the personnel in the current health care sector is the severe progression of diabetes. People can often have diabetes and be completely unaware as the symptoms seem harmless when they are seen on their own. Diabetic retinopathy (DR) is an eye disease that is associated with long-standing diabetes. Retinopathy can occur with all types of diabetes and can lead to blindness if left untreated. The conventional method followed by ophthalmologists is the regular testing of the retina. As this method takes time and energy of the ophthalmologists, a new feature-based automated technique for classification and detection of exudates in color fundus image is proposed in this paper. This method reduces the work of the professionals while examining every fundus image rather than only on abnormal image. The exudates are detected from the color fundus image by applying a few pre-processing techniques that remove the optic disk and similar blood vessels using morphological operations. The pre-processed image was then applied for feature extraction and these features were utilized for classification purpose. In this paper, a novel classification technique such as self-adaptive resource allocation network (SRAN) and meta-cognitive neural network (McNN) classifier is employed for classification of images as exudates, their severity and nonexudates. SRAN classifier makes use of self-adaptive thresholds to choose the appropriate training samples and removes the redundant samples to prevent over-training. These selected samples are availed to improve the classification performance. McNN classifier employs human-like meta-cognition to regulate the sequential learning process. The meta-cognitive component controls the learning process in the cognitive component by deciding what-to-learn, when-to-learn and how-to-learn. It is therefore evident that the implementation of human meta-cognitive learning principle improves efficient learning.


Author(s):  
Aavani B

Abstract: Diabetic retinopathy is the leading cause of blindness in diabetic patients. Screening of diabetic retinopathy using fundus image is the most effective way. As the time increases this DR leads to permanent loss of vision. At present, Diabetic retinopathy is still being treated by hand by an ophthalmologist which is a time-consuming process. Computer aided and fully automatic diagnosis of DR plays an important role in now a day. Data-set containing a collection of fundus images of different severity scale is used to analyze the fundus image of DR patients. Here the deep neural network model is trained by using this fundus image and five-degree classification task is performed. We were able to produce an sensitivity of 90%. Keywords: Confusion matrix, Deep convolutional Neural Network, Diabetic Retinopathy, Fundus image, OCT


2021 ◽  
Vol 68 ◽  
pp. 102600
Author(s):  
Sraddha Das ◽  
Krity Kharbanda ◽  
Suchetha M ◽  
Rajiv Raman ◽  
Edwin Dhas D

2020 ◽  
Author(s):  
Alejandro Noriega ◽  
Daniela Meizner ◽  
Dalia Camacho ◽  
Jennifer Enciso ◽  
Hugo Quiroz-Mercado ◽  
...  

BACKGROUND The automated screening of patients at risk of developing diabetic retinopathy (DR) represents an opportunity to improve their mid-term outcome, and lower the public expenditure associated with direct and indirect costs of common sight-threatening complications of diabetes. OBJECTIVE The present study, aims to develop and evaluate the performance of an automated deep learning–based system to classify retinal fundus images from international and Mexican patients, as referable and non-referable DR cases. In particular, the performance of the automated retina image analysis (ARIA) system is evaluated under an independent scheme (i.e. only ARIA screening) and two assistive schemes (i.e., hybrid ARIA + ophthalmologist screening), using a web-based platform for remote image analysis to determine and compare the sensibility and specificity of the three schemes. METHODS A randomized controlled experiment was performed where seventeen ophthalmologists were asked to classify a series of retinal fundus images under three different conditions: 1) screening the fundus image by themselves (solo), 2) screening the fundus image after being exposed to the retina image classification of the ARIA system (ARIA answer), and 3) screening the fundus image after being exposed to the classification of the ARIA system, as well as its level of confidence and an attention map highlighting the most important areas of interest in the image according to the ARIA system (ARIA explanation). The ophthalmologists’ classification in each condition and the result from the ARIA system were compared against a gold standard generated by consulting and aggregating the opinion of three retina specialists for each fundus image. RESULTS The ARIA system was able to classify referable vs. non-referable cases with an area under the Receiver Operating Characteristic curve (AUROC) of 98.0% and a sensitivity and specificity of 95.1% and 91.5% respectively, for international patient-cases; and an AUROC, sensitivity, and specificity of 98.3%, 95.2%, and 90.0% respectively for Mexican patient-cases. The results achieved outperformed the average performance of the seventeen ophthalmologists enrolled in the study. Additionally, the achieved results suggest that the ARIA system can be useful as an assistive tool, as significant sensitivity improvements were observed in the experimental condition where ophthalmologists were exposed to the ARIA’s system answer previous to their own classification (93.3%), compared to the sensitivity of the condition where participants assessed the images independently (87.3%). CONCLUSIONS These results demonstrate that both use cases of the ARIA system, independent and assistive, present a substantial opportunity for Latin American countries like Mexico, towards an efficient expansion of monitoring capacity for the early detection of diabetes-related blindness.


2018 ◽  
Vol 11 (2) ◽  
pp. 795-805 ◽  
Author(s):  
D. Selvathi ◽  
N. B. Prakash ◽  
V. Gomathi ◽  
G. R. Hemalakshmi

Glaucoma frequently called as the "noiseless hoodlum of sight". The main source of visual impairment worldwide beside Diabetic Retinopathy is Glaucoma. It is discernible by augmented pressure inside the eyeball result in optic disc harm and moderate however beyond any doubt loss of vision. As the renaissance of the worsened optic nerve filaments isn't suitable medicinally, glaucoma regularly goes covered up in its patients anticipating later stages. All around it is assessed that roughly 60.5 million individuals beyond 40 years old experience glaucoma in 2010. This number potentially will lift to 80 million by 2020. Late innovation in medical imaging provides effective quantitative imaging alternatives for the identification and supervision of glaucoma. Glaucoma order can be competently done utilizing surface highlights. The wavelet channels utilized as a part of this paper are daubechies, symlet3 which will expand the precision and execution of classification of glaucomatous pictures. These channels are inspected by utilizing a standard 2-D Discrete Wavelet Transform (DWT) which is utilized to separate features and examine changes. The separated features are sustained into the feed forward neural system classifier that classifies the normal images and abnormal glaucomatous images.


2020 ◽  
Author(s):  
Dr. Vrinda Shiva Shetty ◽  
Harshitha M ◽  
Nitika Choudhary ◽  
Namaratha Karanth ◽  
Akshatha S B
Keyword(s):  

2020 ◽  
Vol 14 ◽  
Author(s):  
Charu Bhardwaj ◽  
Shruti Jain ◽  
Meenakshi Sood

: Diabetic Retinopathy is the leading cause of vision impairment and its early stage diagnosis relies on regular monitoring and timely treatment for anomalies exhibiting subtle distinction among different severity grades. The existing Diabetic Retinopathy (DR) detection approaches are subjective, laborious and time consuming which can only be carried out by skilled professionals. All the patents related to DR detection and diagnoses applicable for our research problem were revised by the authors. The major limitation in classification of severities lies in poor discrimination between actual lesions, background noise and other anatomical structures. A robust and computationally efficient Two-Tier DR (2TDR) grading system is proposed in this paper to categorize various DR severities (mild, moderate and severe) present in retinal fundus images. In the proposed 2TDR grading system, input fundus image is subjected to background segmentation and the foreground fundus image is used for anomaly identification followed by GLCM feature extraction forming an image feature set. The novelty of our model lies in the exhaustive statistical analysis of extracted feature set to obtain optimal reduced image feature set employed further for classification. Classification outcomes are obtained for both extracted as well as reduced feature set to validate the significance of statistical analysis in severity classification and grading. For single tier classification stage, the proposed system achieves an overall accuracy of 100% by k- Nearest Neighbour (kNN) and Artificial Neural Network (ANN) classifier. In second tier classification stage an overall accuracy of 95.3% with kNN and 98.0% with ANN is achieved for all stages utilizing optimal reduced feature set. 2TDR system demonstrates overall improvement in classification performance by 2% and 6% for kNN and ANN respectively after feature set reduction, and also outperforms the accuracy obtained by other state of the art methods when applied to the MESSIDOR dataset. This application oriented work aids in accurate DR classification for effective diagnosis and timely treatment of severe retinal ailment.


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