Papillomavirus infection and reproduction

2020 ◽  
Vol 75 (3) ◽  
pp. 189-195
Author(s):  
Vladislav I. Krasnopolsky ◽  
Nina V. Zarochentseva ◽  
Ksenia V. Krasnopolskaya ◽  
Yulia N. Bashankaeva ◽  
Varvara S. Kuzmicheva
Keyword(s):  
Human Papillomavirus ◽  
Hpv Vaccination ◽  
Carcinogenic Risk ◽  
Human Papillomaviruses ◽  
World Health ◽  
Sexually Transmitted ◽  
Associated Diseases ◽  
Trophoblastic Cells ◽  
Papillomavirus Infection ◽  
Health Organization

The purpose of the review a synthesis of research data on the role of human papillomavirus infection in the reproductive health of women and men. Key Points. Human papillomavirus (HPV) is one of the most common sexually transmitted viruses worldwide. According to the World Health Organization, HPV is the main cause of the development of HPV-associated diseases among both women and men. Viruses are subdivided into HPV with low carcinogenic risk, which cause benign warts, and HPV with high carcinogenic risk, which cause cancer. Different types of human papillomaviruses depending on their characteristic tropism, are divided into skin and mucous types. Viral infection in men leads to a decrease in the quality of sperm (for example, asthenozoospermia) due to apoptosis in sperm cells and due to the development of antisperm immunity. A negative viral effect on the fertility of women is manifested in an increase in the frequency of spontaneous miscarriages and a premature rupture of the amniotic membranes during pregnancy. There is evidence that HPV decreases the number of trophoblastic cells and abnormal trophoblastic-endometrial adhesion is also observed. In trophoblastic cells transfected with high-risk HPV, the level of apoptosis increases. HPV vaccination is safe, and the results show not only protection against HPV-associated diseases in women and men, but also a reduction of gestational complications, reduced preterm birth rates and the protection of newborns from infection.

scholarly journals Preparations for implementing human papillomavirus vaccination should begin

2005 ◽  
Vol 10 (37) ◽  
Author(s):  
M Lehtinen
Keyword(s):  
Human Papillomavirus ◽  
World Health Organization ◽  
Sexually Transmitted Infection ◽  
Hpv Vaccination ◽  
World Health ◽  
Human Papillomavirus Vaccination ◽  
Transmitted Infection ◽  
Sexually Transmitted ◽  
National Programmes ◽  
Health Organization

At a World Health Organization meeting, the latest developments in human papillomavirus (HPV) vaccination were discussed. The leading theme that emerged was how to implement within national programmes the concept of vaccinating adolescents both against a common sexually transmitted infection

scholarly journals Benefits of Gender-Neutral Vaccination Strategy for the Prevention of HPV-Associated Diseases and the Eradication of HPV Infection in General. Current State of HPV Vaccination in the World

2021 ◽  
Vol 18 (3) ◽  
pp. 239-244
Author(s):  
Tatiana E. Privalova ◽  
Olga V. Surovtseva ◽  
Dmitry V. Andriyanov
Keyword(s):  
Hpv Vaccination ◽  
Vaccination Strategy ◽  
Hpv Infection ◽  
Transmitted Infection ◽  
Sexually Transmitted ◽  
Associated Diseases ◽  
Current State ◽  
Papillomavirus Infection ◽  
The World ◽  
Gender Neutral

Papillomavirus infection (HPV infection) is the leading sexually transmitted infection in prevalence. HPV infection and associated diseases, including cancer, remain one of the global problems of our time. This literature review presents relevant data from foreign studies and domestic works on the state of HPV vaccination in the world, the modern vaccines efficacy for the HPV-associated diseases prevention, current vaccination strategies and their efficacy as well. The aim of the article is to determine the advantages of using gender-neutral vaccination strategy over priority-used vaccination strategy for girls only in the prevention of HPV-associated diseases, including cancer, as well as for eradicating HPV infection in general.

Human Papillomavirus Infection and Prevention In The Adolescent

2020 ◽  
Author(s):  
Alexandria Richards ◽  
Joanna Stacey
Keyword(s):  
Human Papillomavirus ◽  
Hpv Vaccination ◽  
Transmitted Disease ◽  
Cervical Dysplasia ◽  
Vaccine Safety ◽  
Genital Warts ◽  
Hpv Infection ◽  
Sexually Transmitted ◽  
Papillomavirus Infection

Human papillomavirus, or HPV, is a common sexually transmitted disease, most often acquired during the adolescence or the early 20s. It can be divided into oncogenic and nononcogenic serotypes. It is responsible for genital warts as well as pathologic diseases that can lead to genital cancers and cancers of the oropharyngeal tract in both males and females. The majority of adolescents who acquire HPV infections do not go on to develop cancer. New discoveries about the virus’ persistence and latency direct how we treat adolescents with HPV infections. Recommendations for prevention of HPV include use of the 9-valent vaccine against the most common oncogenic HPV serotypes. Screening should be delayed until the age of 21, with the exception of immunocompromised women. The HPV vaccination is safe and effective, and does not encourage sexual activity among adolescents. Both boys and girls should be vaccinated against HPV at 11 to 12 years of age but may receive the vaccination as early as 9 or as late as 21 (males) or 26 (females) years of age. The vaccine may now also be given in only two doses if the series was started before the age of 15. Follow-up studies in the years after the vaccine’s introduction have shown large decreases in HPV infection rates. This review contains 7 figures, 7 tables and 63 references Key Words: Oncogenic subtype, Oropharyngeal cancer, Infection persistence, Immune tolerance, Cervical dysplasia, Genital warts, 9-valent vaccine, Vaccine safety  

Anal and oral human papillomavirus infection in men who have sex with men: implications for risk-targeted vaccination

2020 ◽  
Vol 15 (18) ◽  
pp. 1713-1722
Author(s):  
Maria Gabriella Donà ◽  
Francesca Rollo ◽  
Alessandra Latini ◽  
Maria Benevolo ◽  
Barbara Pichi ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
Linear Array ◽  
Hpv Vaccination ◽  
Risk Groups ◽  
Sexually Active ◽  
Transmitted Infection ◽  
Sexually Transmitted ◽  
Papillomavirus Infection ◽  
Significant Burden ◽  
Sex With Men

Aim: Men who have sex with men (MSM) harbor a significant burden of human papillomavirus (HPV)-related diseases that could be prevented by vaccination. Materials & methods: Prevalence of HPVs targeted by the quadrivalent (4vHPV) and nonavalent vaccines (9vHPV) was assessed in anal (n = 443) and oral (n = 193) specimens of immunocompetent, sexually active MSM, using the Linear Array. Results: Of the anal samples, 34.1 and 46.0% were positive for at least one genotype of those covered by the 4vHPV and 9vHPV, respectively. At least one of the HPVs targeted by the 9vHPV was detected in 5.7% of the oral specimens. Conclusion: The majority of the subjects were not currently infected by HPV-16 and other vaccine-preventable HPVs. Universal HPV vaccination should be strongly promoted in order to achieve protection for all risk groups. In the meanwhile, vaccination should be offered to sexually active adult MSM attendees of sexually transmitted infection centers, although its potential benefit for these subjects needs to be further investigated.

What a patient needs to know about the virus human papillomas and cervical cancer?

GYNECOLOGY ◽  
2021 ◽  
Vol 23 (1) ◽  
pp. 83-87
Author(s):  
Sergei P. Sinchikhin ◽  
Lusine V. Stepanyan
Keyword(s):  
Cervical Cancer ◽  
Human Papillomavirus ◽  
Diagnostic Methods ◽  
World Health ◽  
Educational Work ◽  
Systematic Analysis ◽  
Human Papillomavirus Infection ◽  
Papillomavirus Infection ◽  
Health Organization ◽  
Educational Information

According to experts of the World Health Organization, cervical cancer is the only cancer that can be completely prevented through the introduction of mass screening and educational information in the population. One of the activities of the obstetrician-gynecologist is the conduct of health education. However, for a variety of reasons, a practical doctor may have difficulty preparing for informational and educational meetings with patients. Aim. To prepare a clinical lecture for the obstetrician-gynecologist, which can be used in educational work with the population on the prevention of human papillomavirus infection and cervical cancer. Materials and methods. The information material includes data from foreign and domestic scientific articles available at PubMed on this topic and published over the past 10 years. Results. A systematic analysis of the data contained in the modern literature on human papillomavirus, human papillomavirus infection and cervical cancer has been carried out. Information is presented on the prevalence of diseases, diagnostic methods, and features of the course of human papillomavirus infection, the role of human papillomavirus in the development of cervical cancer. Attention is drawn to the importance of preventive examinations. Part of the information is presented in the form of answers to patients questions, which makes the information presented especially memorable. Conclusion. It is hoped that the prepared lecture will be useful for the educational work of the obstetrician-gynecologist and will increase the educational information of the population on the prevention of cervical cancer.

scholarly journals Achievements and Prospects of Vaccination against Human Papillomavirus Infection and Associated Diseases

2020 ◽  
Vol 19 (2) ◽  
pp. 110-118
Author(s):  
G. N. Minkina
Keyword(s):  
Human Papillomavirus ◽  
Hpv Vaccination ◽  
Evidence Base ◽  
Full Potential ◽  
Cervical Lesions ◽  
Vaccination Programs ◽  
Associated Diseases ◽  
Papillomavirus Infection ◽  
Precancerous Cervical Lesions ◽  
The Impact

Relevance. The past decade has been marked by rapid advances in the prevention of human papillomavirus (HPV) infections and associated diseases.Aims. To sum up the accumulated experience and evidence base of the impact of national HPV vaccination programs on the prevalence of HPV infections, the incidence of genital warts and precancerous cervical lesions. 3.Conclusions. To reach its full potential and have a greater and earlier impact on the population, gender-neutral and, if possible, multi-cohort HPV vaccination should be included in the national immunization calendar.

scholarly journals Achievements and Prospects of Vaccination against Human Papillomavirus Infection and Associated Diseases

2020 ◽  
Vol 19 (2) ◽  
pp. 110-118
Author(s):  
G. N. Minkina
Keyword(s):  
Human Papillomavirus ◽  
Hpv Vaccination ◽  
Evidence Base ◽  
Full Potential ◽  
Cervical Lesions ◽  
Vaccination Programs ◽  
Associated Diseases ◽  
Papillomavirus Infection ◽  
Precancerous Cervical Lesions ◽  
The Impact

Relevance. The past decade has been marked by rapid advances in the prevention of human papillomavirus (HPV) infections and associated diseases.Aims. To sum up the accumulated experience and evidence base of the impact of national HPV vaccination programs on the prevalence of HPV infections, the incidence of genital warts and precancerous cervical lesions. 3.Conclusions. To reach its full potential and have a greater and earlier impact on the population, gender-neutral and, if possible, multi-cohort HPV vaccination should be included in the national immunization calendar.

Sign in / Sign up

Export Citation Format

Share Document