scholarly journals Coronary artery status in patients with coronary heart disease and chronic obstructive pulmonary disease: results of selective coronary angiography

2012 ◽  
Vol 11 (5) ◽  
pp. 29-32
Author(s):  
N. Yu. Grigorieva ◽  
E. G. Sharavrin ◽  
A. N. Kuznetsov ◽  
T. V. Koroleva ◽  
P. A. Blinov ◽  
...  

Aim. To study the specifics of coronary artery pathology in patients with coronary heart disease (CHD) and chronic obstructive pulmonary disease (COPD), using the data of selective coronary angiography (CAG). Material and methods. In total, 907 CHD patients were examined. Group I included 251 participants with CHD and COPD; Group II included 656 individuals with CHD only. CAG was performed in 582 patients (64,2%): 184 from Group I (73,3%) and 398 from Group II (60,7%). Results. In patients with the combination of cardiac and pulmonary disease, the prevalence of two- and three-vessel pathology was higher, compared to CHD-only patients: 70,6% in Group I vs. 53,8% in Group II (p=0,002). In Group I, the Syntax Scale score was significantly higher than in Group II (24,7±4,1 vs. 18,7±3,1, respectively). Conclusion. Patients with combined cardiac and pulmonary pathology demonstrated a more severe coronary artery atherosclerosis, based on such CAG parameters as stenosis degree, number of involved vessels, size and location of lesions, and proximal stenosis.

2011 ◽  
Vol 10 (3) ◽  
pp. 47-50
Author(s):  
A. N. Kuznetsov ◽  
N. Yu. Grigoryeva ◽  
E. G. Sharabrinv

Aim. To study the specific clinical features in patients with coronary heart disease, CHD (stable effort angina, SEA) and chronic obstructive pulmonary disease (COPD), in order to improve early diagnostics of this combined pathology. Material and methods. The study was a retrospective analysis of 958 medical histories. Co-existing COPD was registered in 251 patients (26,3 %). Therefore, Group I included 251 patients with SEA and COPD (26,3 %), while Group II included 707 SEA patients without COPD (73,7 %). Results. In Group I, there were more men than women, by 5,7 % (р<0,05). No significant differences in age and angina functional class were observed between Groups I and II. In patients with SEA and COPD, the prevalence of arterial hypertension and myocardial infarction was higher than in Group II (р<0,05). In addition, Group I was characterised by higher prevalence of dyspnoea, palpitation, C-reactive protein elevation, and lipid metabolism disturbances. Conclusion. Among chronic CHD patients hospitalized to the cardiology unit, co-existing COPD was registered in 26,3 %. The combination with COPD aggravated the clinical course of CHD. The study results support the use of lung function assessment in smoking CHD patients, to diagnose co-existing COPD.


2019 ◽  
Vol 69 (1) ◽  
pp. 149-157 ◽  
Author(s):  
Sebastian Rutkowski ◽  
Anna Rutkowska ◽  
Dariusz Jastrzębski ◽  
Henryk Racheniuk ◽  
Witold Pawełczyk ◽  
...  

Abstract The aim of the study was to evaluate the effects of rehabilitation in patients with chronic obstructive pulmonary disease (COPD) using the Kinect system during stationary rehabilitation. The study included 68 patients with COPD (35 men, 33 women, mean age 61.3 ± 3.7). The subjects were randomly assigned to one of the two experimental groups described below. Group I included 34 patients – non‐participants in Kinect training. Group II included 34 patients – participants in Kinect training. In all patients before and after rehabilitation physical fitness was assessed using the Senior Fitness Test (SFT). The Xbox 360 and Kinect motion sensor were used to carry out virtual reality training. In group I, statistically significant improvements in SFT performance were observed. Patients in group II also showed statistically significant improvement in physical fitness in all attempts of the SFT. Virtual rehabilitation training in patients with COPD seems to be a practical and beneficial intervention capable of enhancing mobility and physical fitness.


2021 ◽  
Vol 20 (2) ◽  
Author(s):  
Т.О. Ilashchuk ◽  
O.P. Mykytyuk ◽  
Y.V. Chobanu

The aim – to analyze the literature data sources concerning the peculiarities of thecombined course of chronic obstructive pulmonary disease (COPD) and coronaryheart disease (CHD), taking into account the endothelial dysfunction of systemicinflammation and oxidative stress.Conclusions. The main mechanisms involved in the progression of the combinedcourse of chronic obstructive pulmonary disease and coronary heart disease are theendothelial dysfunction, the systemic inflammation and desynchronosis. The pleiotropiceffects and diverce molecular interactions of sirtuins have distinct physiological effects,such as preventing the development and progression of emphysema in COPD and avoiding the progression of myocardical hypertrophy and heart failure. The researchof intermolecular interactions with the help of Sirtuin is a promising area for findingnew effective diagnostic and prognostic criteria and therapeutic strategies for COPDand CVD.


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