scholarly journals Relieving the first bottleneck in the drug discovery pipeline: using array technologies to rationalize membrane protein production

2009 ◽  
Vol 6 (5) ◽  
pp. 501-505 ◽  
Author(s):  
Nicklas Bonander ◽  
Roslyn M Bill
Keyword(s):  
Drug Discovery ◽  
Membrane Protein ◽  
Protein Production ◽  
Discovery Pipeline

Membrane protein production and formulation for drug discovery

2021 ◽  
Vol 42 (8) ◽  
pp. 657-674
Author(s):  
Ellen Gulezian ◽  
Christina Crivello ◽  
Janna Bednenko ◽  
Claudia Zafra ◽  
Yihui Zhang ◽  
...  
Keyword(s):  
Drug Discovery ◽  
Membrane Protein ◽  
Protein Production

The Discovery Channel: microfluidics and microengineered systems in drug screening

2015 ◽  
Vol 7 (3) ◽  
pp. 285-288 ◽  
Author(s):  
Christopher Moraes
Keyword(s):  
Drug Discovery ◽  
Engineering Design ◽  
High Throughput ◽  
Drug Screening ◽  
High Throughput Screening ◽  
Recent Literature ◽  
Analytical Strategies ◽  
Discovery Pipeline

We highlight exciting findings and promising approaches in the recent literature in which researchers integrate advanced micro-engineering, design, and analytical strategies to improve the relevance and utility of high-throughput screening in the drug discovery pipeline.

scholarly journals Membrane protein production inEscherichia colicell-free lysates

FEBS Letters ◽  
2015 ◽  
Vol 589 (15) ◽  
pp. 1713-1722 ◽  
Author(s):  
Erik Henrich ◽  
Christopher Hein ◽  
Volker Dötsch ◽  
Frank Bernhard
Keyword(s):  
Membrane Protein ◽  
Protein Production

Development of Escherichia coli Strains That Withstand Membrane Protein-Induced Toxicity and Achieve High-Level Recombinant Membrane Protein Production

2016 ◽  
Vol 6 (2) ◽  
pp. 284-300 ◽  
Author(s):  
Dimitra Gialama ◽  
Kalliopi Kostelidou ◽  
Myrsini Michou ◽  
Dafni Chrysanthi Delivoria ◽  
Fragiskos N. Kolisis ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Membrane Protein ◽  
Protein Production ◽  
High Level

Towards improved membrane protein production in Pichia pastoris: General and specific transcriptional response to membrane protein overexpression

2014 ◽  
Vol 31 (6) ◽  
pp. 538-552 ◽  
Author(s):  
Thomas Vogl ◽  
Gerhard G. Thallinger ◽  
Guenther Zellnig ◽  
David Drew ◽  
James M. Cregg ◽  
...  
Keyword(s):  
Pichia Pastoris ◽  
Membrane Protein ◽  
Protein Production ◽  
Transcriptional Response ◽  
Protein Overexpression

Drug-Discovery Pipeline for Novel Inhibitors of the Androgen Receptor

2016 ◽  
pp. 31-54 ◽  
Author(s):  
Kush Dalal ◽  
Ravi Munuganti ◽  
Hélène Morin ◽  
Nada Lallous ◽  
Paul S. Rennie ◽  
...  
Keyword(s):  
Androgen Receptor ◽  
Drug Discovery ◽  
Discovery Pipeline
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