scholarly journals Amplitude-integrated electroencephalography for neonatal seizure detection. An electrophysiological point of view

2019 ◽  
Vol 77 (2) ◽  
pp. 122-130 ◽  
Author(s):  
Sebastián Gacio

ABSTRACT Seizures in the newborn are associated with high morbidity and mortality, making their detection and treatment critical. Seizure activity in neonates is often clinically obscured, such that detection of seizures is particularly challenging. Amplitude-integrated EEG is a technique for simplified EEG monitoring that has found an increasing clinical application in neonatal intensive care. Its main value lies in the relative simplicity of interpretation, allowing nonspecialist members of the care team to engage in real-time detection of electrographic seizures. Nevertheless, to avoiding misdiagnosing rhythmic artifacts as seizures, it is necessary to recognize the electrophysiological ictal pattern in the conventional EEG trace available in current devices. The aim of this paper is to discuss the electrophysiological basis of the differentiation of epileptic seizures and extracranial artifacts to avoid misdiagnosis with amplitude-integrated EEG devices.

1989 ◽  
Vol 114 (2) ◽  
pp. 281-287 ◽  
Author(s):  
Paul D. Conrad ◽  
John W. Sparks ◽  
Iris Osberg ◽  
Lisa Abrams ◽  
William W. Hay

Author(s):  
Diana Cecagno ◽  
Carla Vanice Cardoso Fröhlinch ◽  
Susana Cecagno ◽  
Juliana Marques WeyKamp ◽  
Camilla Benigno Biana ◽  
...  

Objetivo: conhecer a vivência das mães de bebês prematuros durante a hospitalização em unidade de terapia intensiva neonatal. Métodos: estudo descritivo, exploratório, com abordagem qualitativa. A coleta de dados foi realizada por meio de entrevista semiestruturada, com puérperas que tiveram seus filhos internados na unidade de terapia neonatal de um Hospital Escola do Sul do Brasil no período da coleta. Os dados foram analisados por meio de análise temática. Resultados: A vivência de mães de filhos prematuros hospitalizados e percepções de mães em relação aos cuidados de filhos prematuros na Unidade de Terapia Intensiva. As mães compreendem a necessidade de internação, mas esta gera preocupações, dificuldades e sentimentos de choque, medo e desinformação. Conclusão: apesar da necessidade de internação e da fragilidade emocional causada pela separação da mãe-bebê não houve comprometimento no desenvolvimento do vinculo da díade.


2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Keisuke Mihara ◽  
Haruna Nakahara ◽  
Kouhei Iwashita ◽  
Kenji Shigematsu ◽  
Ken Yamaura ◽  
...  

Abstract Background Continuous electroencephalogram (EEG) monitoring is useful for assessing the level of sedation and detecting non-convulsive epileptic seizures and cerebral ischemia in the intensive care unit. This report describes a case of cerebral hemorrhagic infarction diagnosed after the detection of high-amplitude slow waves on processed EEG during sedation. Case presentation A 68-year-old man who underwent cardiac surgery was sedated in the intensive care unit following an invasive procedure. High-amplitude slow waves appeared on processed EEG monitoring before the detection of anisocoria. Computed tomography revealed a cerebral hemorrhagic infarction. Conclusions In the management of critically ill patients, continuous EEG monitoring with forehead electrodes may be useful in the early detection of brain lesions.


2017 ◽  
Vol 15 (1) ◽  
pp. 36-39
Author(s):  
Ganesh Prasad Neupane ◽  
Maya Rai ◽  
Dabal Bahadur Dhami ◽  
Ritesh Singh

Introduction: Neonates are most vulnerable to infections due to poor immune system leading to high morbidity and mortality, which justifies early diagnosis and prompt treatment with antibiotics. Antibiotics are the most frequently used drugs in Neonatal Intensive care units. Aim and Objective: The objective of present study was to identify the pattern of use of antimicrobial agents in neonates at the neonatal intensive care unit (NICU) of NGMC. Materials and Methods: A hospital-based, retrospective study (prescription audit) was conducted over a period of 5-month duration at Nepalgunj Medical College by reviewing case records of NICU. Data were collected and analyzed. Results: A total of 150 case records were reviewed and were included in the study. Out of the 150, Neonates 86 (57.33%) were male babies and 64 (42.67%) were female babies. Maximum number (72.66%) neonates admitted to NICU were of low birth weight and most common reason for NICU admission was neonatal septicaemia. The majority of neonates (68.67%) received 2 antimicrobial agents (AMAs), 21.33% received 3 AMAs and average number of antibiotic per case was 2.44. The most commonly prescribed antimicrobial agent was Cefotaxime (58.66%), followed by Amikacin (48%), Ceftriaxone (32%). In fixed dose combination Piperacillin + Tazobactum (28%) was most commonly prescribed. All of the antimicrobial agents were prescribed by brand name.  Conclusion: Measures need to be undertaken to encourage physicians to prescribe AMAs in generic names to minimize health care cost. Present study suggests that Antibiotics policy to be framed & periodically reviewed: to reduce unnecessary use of antibiotics and associated problems.


Folia Medica ◽  
2020 ◽  
Vol 62 (4) ◽  
pp. 753-761
Author(s):  
Vanya Rangelova ◽  
Ralitsa Raycheva ◽  
Ani Kevorkyan ◽  
Maya Krasteva ◽  
Tihomir Dermendzhiev

Introduction: Nosocomial infections (NI) are frequent complications in neonatal intensive care units (NICU) which result in high morbidity and mortality. Aim: To determine and analyze the incidence, risk factors and etiologic agents of NI in newborns admitted in the NICU to help plan-ning future surveillance and prevention strategies. Materials and methods: A prospective cohort study was carried out at the NICU of St George University Hospital, Plovdiv, Bul-garia from January 1, 2017 to June 31, 2018. The number of neonates included in the study was 507. Descriptive statistics such as count,  percent, mean and standard deviation was used. Chi-square test was performed to prove associations. Odds ratios, with 95% confidence intervals, were computed from the results of the binominal logistic regression analyses. Results: Of the 507 hospitalized newborns in NICU, 48 presented with 54 NI. The incidence and the density incidence rates were 9.5% and 7.67 per 1,000 patient-days, respectively. Nosocomial infections were detected in neonates from all birth weight (BW) classes, but it was low BW and premature neonates that were at major risk to acquire them. The most common infection sites were ventilator-asso-ciated pneumonia (VAP) (67.27%), bloodstream infection (23.64%) and conjunctivitis (9.09%). Major pathogens were Gram-negative such as Klebsiella pneumoniae, E. coli, Pseudomonas aeruginosa and Acinetobacter baumannii. In the multivariate logistic regression analysis NIs were strongly associated with intubation, presence of a venous catheter, the duration of antibiotic treatment and increased CRP> 10 mg/l. Conclusions: This report highlights the burden of NIs, identifies the major focus for future NI control and prevention programs.


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