Swallowing in behavioral variant frontotemporal dementia

2021 ◽  
Vol 79 (1) ◽  
pp. 8-14
Author(s):  
Sheilla de Medeiros Correia MARIN ◽  
Letícia Lessa MANSUR ◽  
Fabricio Ferreira de OLIVEIRA ◽  
Luis Fabiano MARIN ◽  
José Roberto WAJMAN ◽  
...  
Keyword(s):  
Frontotemporal Dementia ◽  
Mental State ◽  
Mini Mental State Examination ◽  
Rating Scale ◽  
Behavioral Variant Frontotemporal Dementia ◽  
Severe Stage ◽  
Swallowing Problems ◽  
Behavioral Features ◽  
Swallowing Difficulties ◽  
State Examination

ABSTRACT Background: Swallowing and feeding problems may occur with the progression of behavioral variant frontotemporal dementia (bvFTD) and can impair the anticipatory and oral preparatory phases of swallowing. Objective: To characterize swallowing problems and the feeding situation of patients with bvFTD and to correlate the swallowing problems with functionality, executive functions, cognitive and behavioral features. Methods: Consecutive outpatients with bvFTD in mild, moderate and severe dementia stages were recruited along with their caregivers. Patients and caregivers were screened with the following scales: “Mini-Mental State Examination”, “Severe Mini-Mental State Examination”, “FTLD-modified Clinical Dementia Rating”, “Neuropsychiatric Inventory”, “Frontal Assessment Battery”, “Index of Independence in Activities of Daily Living”, “Swallowing Rating Scale” and “Assessment of Feeding and Swallowing Difficulties in Dementia”. Results: Overall, thirty patients with bvFTD were included along with their caregivers. Patients with bvFTD showed feeding and swallowing difficulties such as: messy to eat, passivity, coughing and choking, difficulty with some food consistencies and with specific food. Swallowing problems in bvFTD correlated with impaired functionality (p<0.05) and cognition (p<0.05), executive dysfunction (p<0.01) and behavioral features (p<0.01). Caregivers had great difficulty in managing the feeding situation during mealtime, with different characteristics in each dementia stage. Conclusion: Patients with bvFTD had inappropriate speed eating, passivity, coughing and choking starting in the mild dementia stage, and these problems worsen in the severe stage. Such difficulties affected caregiver performance during mealtime. The correlations indicated that swallowing difficulties tend to follow cognitive and behavioral decline in patients with bvFTD.

Conversion between Addenbrooke's Cognitive Examination III and Mini-Mental State Examination

2017 ◽  
Vol 30 (8) ◽  
pp. 1227-1233 ◽  
Author(s):  
Jordi A. Matías-Guiu ◽  
Vanesa Pytel ◽  
Ana Cortés-Martínez ◽  
María Valles-Salgado ◽  
Teresa Rognoni ◽  
...  
Keyword(s):  
Frontotemporal Dementia ◽  
Mental State ◽  
Mini Mental State Examination ◽  
Primary Progressive Aphasia ◽  
Healthy Controls ◽  
Behavioral Variant Frontotemporal Dementia ◽  
Progressive Aphasia ◽  
Conversion Table ◽  
State Examination ◽  
Addenbrooke’S Cognitive Examination

ABSTRACTBackground:We aim to provide a conversion between Addenbrooke's Cognitive Examination III (ACE-III) and Mini-Mental State Examination (MMSE) scores, to predict the MMSE result based on ACE-III, thus avoiding the need for both tests, and improving their comparability.Methods:Equipercentile equating method was used to elaborate a conversion table using a group of 400 participants comprising healthy controls and Alzheimer's disease (AD) patients. Then, reliability was assessed in a group of 100 healthy controls and patients with AD, 52 with primary progressive aphasia and 22 with behavioral variant frontotemporal dementia.Results:The conversion table between ACE-III and MMSE denoted a high reliability, with intra-class correlation coefficients of 0.940, 0.922, and 0.902 in the groups of healthy controls and AD, behavioral variant frontotemporal dementia, and primary progressive aphasia, respectively.Conclusion:Our conversion table between ACE-III and MMSE suggests that MMSE may be estimated based on the ACE-III score, which could be useful for clinical and research purposes.

scholarly journals Swallowing in moderate and severe phases of Alzheimer's disease

2010 ◽  
Vol 68 (6) ◽  
pp. 855-861 ◽  
Author(s):  
Sheilla de Medeiros Correia ◽  
Lilian Schafirovits Morillo ◽  
Wilson Jacob Filho ◽  
Leticia Lessa Mansur
Keyword(s):  
Activities Of Daily Living ◽  
Mental State ◽  
Daily Living ◽  
Mini Mental State Examination ◽  
Rating Scale ◽  
Outcome Questionnaire ◽  
Clinical Dementia Rating ◽  
Functional Aspects ◽  
Swallowing Difficulties ◽  
State Examination

OBJECTIVE: To characterize the problems of feeding and swallowing in individuals with moderate and severe Alzheimer´s disease (AD) and to correlate these with functional aspects. METHOD: Fifty patients with AD and their caregivers participated in this study. The instruments used were: Clinical Dementia Rating (CDR), Mini-Mental State Examination, Index of Activities of Daily Living, Assessment of Feeding and Swallowing Difficulties in Dementia, Functional Outcome Questionnaire for Aphasia, and Swallowing Rating Scale. RESULTS: Problems with passivity, distraction and refusal to eat were encountered in the CDR2 group. Distraction, passivity and inappropriate feeding velocity were predominant in the CDR3 group. The problems were correlated with communication, swallowing severity of AD individuals and caregiver schooling. CONCLUSION: Given the inexorable functional alterations during the course of the disease, it is vital to observe these in patients with a compromised feeding and swallowing mechanism. The present study supplies the instruments to orient caregivers and professionals.

The agreement of the Mattis Dementia Rating Scale with the Mini-Mental State Examination

2002 ◽  
Vol 17 (7) ◽  
pp. 685-686 ◽  
Author(s):  
W. Freidl ◽  
W.-J. Stronegger ◽  
A. Berghold ◽  
B. Reinhart ◽  
K. Petrovic ◽  
...  
Keyword(s):  
Mental State ◽  
Mini Mental State Examination ◽  
Rating Scale ◽  
Mattis Dementia Rating Scale ◽  
Dementia Rating Scale ◽  
State Examination

scholarly journals Dopaminergic imaging and clinical predictors for phenoconversion of REM sleep behaviour disorder

Brain ◽  
2020 ◽  
Author(s):  
Dario Arnaldi ◽  
Andrea Chincarini ◽  
Michele T Hu ◽  
Karel Sonka ◽  
Bradley Boeve ◽  
...  
Keyword(s):  
Risk Factors ◽  
Logistic Regression ◽  
Mental State ◽  
Rem Sleep ◽  
Mini Mental State Examination ◽  
Rating Scale ◽  
Bayesian Classifier ◽  
Examination Score ◽  
Sleep Behaviour ◽  
State Examination

Abstract This is an international multicentre study aimed at evaluating the combined value of dopaminergic neuroimaging and clinical features in predicting future phenoconversion of idiopathic REM sleep behaviour (iRBD) subjects to overt synucleinopathy. Nine centres sent 123I-FP-CIT-SPECT data of 344 iRBD patients and 256 controls for centralized analysis. 123I-FP-CIT-SPECT images were semiquantified using DaTQUANTTM, obtaining putamen and caudate specific to non-displaceable binding ratios (SBRs). The following clinical variables were also analysed: (i) Movement Disorder Society-sponsored revision of the Unified Parkinson’s Disease Rating Scale, motor section score; (ii) Mini-Mental State Examination score; (iii) constipation; and (iv) hyposmia. Kaplan-Meier survival analysis was performed to estimate conversion risk. Hazard ratios for each variable were calculated with Cox regression. A generalized logistic regression model was applied to identify the best combination of risk factors. Bayesian classifier was used to identify the baseline features predicting phenoconversion to parkinsonism or dementia. After quality check of the data, 263 iRBD patients (67.6 ± 7.3 years, 229 males) and 243 control subjects (67.2 ± 10.1 years, 110 males) were analysed. Fifty-two (20%) patients developed a synucleinopathy after average follow-up of 2 years. The best combination of risk factors was putamen dopaminergic dysfunction of the most affected hemisphere on imaging, defined as the lower value between either putamina (P &lt; 0.000001), constipation, (P &lt; 0.000001) and age over 70 years (P = 0.0002). Combined features obtained from the generalized logistic regression achieved a hazard ratio of 5.71 (95% confidence interval 2.85–11.43). Bayesian classifier suggested that patients with higher Mini-Mental State Examination score and lower caudate SBR asymmetry were more likely to develop parkinsonism, while patients with the opposite pattern were more likely to develop dementia. This study shows that iRBD patients older than 70 with constipation and reduced nigro-putaminal dopaminergic function are at high risk of short-term phenoconversion to an overt synucleinopathy, providing an effective stratification approach for future neuroprotective trials. Moreover, we provide cut-off values for the significant predictors of phenoconversion to be used in single subjects.

scholarly journals P2-103: Korean version of Mini-Mental State Examination and Clinical Dementia Rating Scale Sum of Boxes scores in staging the dementia

2009 ◽  
Vol 5 (4S_Part_10) ◽  
pp. P292-P292 ◽  
Author(s):  
Hee Jin Kang ◽  
Young-Hee Chang ◽  
Ha-Ry Na ◽  
Min Jae Baek ◽  
Hyun Jung Kim ◽  
...  
Keyword(s):  
Mental State ◽  
Mini Mental State Examination ◽  
Rating Scale ◽  
Clinical Dementia Rating ◽  
Korean Version ◽  
Dementia Rating Scale ◽  
State Examination

The neurological examination adapted for neuropsychiatry

CNS Spectrums ◽  
2018 ◽  
Vol 23 (3) ◽  
pp. 219-227 ◽  
Author(s):  
Sheldon Benjamin ◽  
Margo D. Lauterbach
Keyword(s):  
Neurological Examination ◽  
Mental State ◽  
Cognitive Assessment ◽  
Mini Mental State Examination ◽  
Screening Tool ◽  
Rating Scale ◽  
Subcortical Structures ◽  
Dysmorphic Features ◽  
Examination Techniques ◽  
State Examination

The neuropsychiatric examination includes standard neurological and cognitive examination techniques with several additional observations and tasks designed to capture abnormalities common among patients with neuropsychiatric disorders or neurocognitive complaints. Although useful as a screening tool, a single standardized rating scale such as the Mini Mental State Examination (MMSE) or the Montreal Cognitive Assessment (MoCA) is insufficient to establish a neuropsychiatric diagnosis. Extra attention is paid to findings commonly seen in the setting of psychiatric disorders, dementias, movement disorders, or dysfunction of cortical or subcortical structures. Dysmorphic features, dermatologic findings, neurodevelopmental signs, signs of embellishment, and expanded neurocognitive testing are included. The neuropsychiatric clinician utilizes the techniques described in this article to adapt the examination to each patient’s situation, choosing the most appropriate techniques to supplement the basic neurological and psychiatric examinations in support of diagnostic hypotheses being considered. The added examination techniques facilitate diagnosis of neurocognitive disorders and enable neuropsychiatric formulation.

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