Effect of Using Biomimetic Analogs on Dentin Remineralization with Bioactive Cements

Abstract This study evaluated the impact of using biomimetic analogs (poly-acrylic acid and sodium tri-meta-phosphate) on dentin remineralization using two cement materials, the first is calcium silicate based and the second is calcium hydroxide based materials. Two standardized occlusal cavities (mesial and distal) were prepared within dentin after removal of occlusal enamel. Artificial demineralized dentin was induced through pH cycling (8 h in demineralizing and 16 h in remineralizing solutions). Demineralized cavities were divided into four groups; two groups received cement materials. The other groups were first treated with biomimetic analogs then restored with pulp cement materials. Teeth were sectioned buccolingually into two halves. Treated cavities with analogs were stored in simulated body fluid containing poly-acrylic acid. Untreated cavities were stored in simulated body fluid only. Ground unstained sections of demineralized dentin were examined using light microscope. Specimens were examined after 1, 6 and 12 weeks of storage using energy dispersive X-ray Spectroscopy (EDX) and Vickers microhardness was evaluated. Two-way ANOVA was used to analyze data statistically. Calcium silicate-based cement group with biomimetic analogs showed the highest statistically significant calcium and phosphorous wt% in addition to highest surface hardness values after 12 weeks of storage. Demineralized dentin ground sections showed increase in light zones after total period of storage. Calcium silicate-based cement showed the best ability to enrich the artificial carious dentin with ions for remineralization. Using biomimetic analogs had a significant impact on demineralized dentin surface hardness improvement.

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Synthesis and Characterization of Poly(Acrylic Acid)/Organo-Modified Nanohydroxyapatite Nanocomposites: Thermal, Optical and Biocompatibility Properties

Advances in Materials Science ◽

10.1515/adms-2017-0041 ◽

2018 ◽

Vol 18 (3) ◽

pp. 54-67 ◽

Cited By ~ 2

Author(s):

M. E. Diken ◽

S. Doğan ◽

Y. Turhan ◽

M. Doğan

Keyword(s):

Glass Transition ◽

Transition Temperature ◽

Glass Transition Temperature ◽

Simulated Body Fluid ◽

Acrylic Acid ◽

Body Fluid ◽

Synthesis And Characterization ◽

Uv Absorbance ◽

Poly Acrylic Acid

AbstractThe aim of this study was to investigate the structural, thermal, optical and biocompatibility properties of poly(acrylic acid)(PAA)/organo-modified nanohydroxyapatite (OM-nHAp) nanocomposites synthesized by solvent intercalation method. The characterization of PAA/OM-nHAp nanocomposites was made by different techniques. SEM and TEM results showed that OM-nHAp particles were dispersed in the nanoscale into PAA matrix and that they were uniformly distributed within film. Glass transition temperature of PAA increased with OM-nHAp content. Ultraviolet (UV) absorbance experiments showed that PAA had a higher UV transmission than its nanocomposites. The biocompatibility of nanocomposites was also examined in simulated body fluid.

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Hydroxyapatite Formation on Acrylic Acid-grafted Porous PLLA Scaffolds in Simulated Body Fluid

3rd Kuala Lumpur International Conference on Biomedical Engineering 2006 - IFMBE Proceedings ◽

10.1007/978-3-540-68017-8_28 ◽

2007 ◽

pp. 109-112 ◽

Cited By ~ 2

Author(s):

Hyun Jung Jung ◽

Kwideok Park ◽

Jun Sik Son ◽

Jae-Jin Kim ◽

Dong Keun Han

Keyword(s):

Simulated Body Fluid ◽

Acrylic Acid ◽

Body Fluid ◽

Hydroxyapatite Formation

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Preparation of Calcium Silicate Nanobelts and the In Vitro Behavior in a Simulated Body Fluid

Chemistry Letters ◽

10.1246/cl.2007.1090 ◽

2007 ◽

Vol 36 (9) ◽

pp. 1090-1091 ◽

Cited By ~ 5

Author(s):

Huiqin Ling ◽

Qun Liu ◽

Chengkang Chang ◽

Dali Mao

Keyword(s):

Simulated Body Fluid ◽

Calcium Silicate ◽

Body Fluid

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A multinuclear solid state NMR spectroscopic study of the structural evolution of disordered calcium silicate sol–gel biomaterials

Physical Chemistry Chemical Physics ◽

10.1039/c4cp04492d ◽

2015 ◽

Vol 17 (4) ◽

pp. 2540-2549 ◽

Cited By ~ 21

Author(s):

Zhongjie Lin ◽

Julian R. Jones ◽

John V. Hanna ◽

Mark E. Smith

Keyword(s):

Solid State ◽

Simulated Body Fluid ◽

Spectroscopic Study ◽

Calcium Silicate ◽

Solid State Nmr ◽

Body Fluid ◽

Sol Gel ◽

Structural Evolution ◽

Subsequent Reaction ◽

Bioactive Glasses

Multinuclear solid state NMR, especially 17O, shows the structural evolution of calcium silicate sol–gel bioactive glasses during stabilisation and subsequent reaction with simulated body fluid.

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Preparation, thermal, spectral and microscopic studies of calcium silicate hydrate–poly(acrylic acid) nanocomposite materials

Journal of Thermal Analysis and Calorimetry ◽

10.1007/s10973-005-7353-9 ◽

2006 ◽

Vol 85 (1) ◽

pp. 99-105 ◽

Cited By ~ 119

Author(s):

S. C. Mojumdar ◽

L. Raki

Keyword(s):

Acrylic Acid ◽

Calcium Silicate ◽

Calcium Silicate Hydrate ◽

Nanocomposite Materials ◽

Microscopic Studies ◽

Poly Acrylic Acid

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Radiata pine wood treatment with a dispersion of aqueous styrene/acrylic acid copolymer

Holzforschung ◽

10.1515/hf-2017-0142 ◽

2018 ◽

Vol 72 (5) ◽

pp. 387-396 ◽

Cited By ~ 10

Author(s):

Wenbo Che ◽

Zefang Xiao ◽

Guanghui Han ◽

Zhongguo Zheng ◽

Yanjun Xie

Keyword(s):

Acrylic Acid ◽

Elevated Temperatures ◽

Wood Quality ◽

Surface Hardness ◽

Treated Wood ◽

Wood Properties ◽

Weight Percent ◽

Radiata Pine ◽

Mechanical Reinforcement ◽

The Impact

AbstractWood of radiata pine (Pinus radiataDon) was treated with an aqueous styrene/acrylic acid (St/AA) copolymer dispersion leading to weight percent gains (WPGs) of 10–42%. The reactivity of St/AA in wood and the modifying effects on wood properties were investigated. The St/AA precipitated in the cell lumens and condensed under catalysis at elevated temperatures was shown via scanning electron microscopy (SEM) and Fourier transform infrared (FTIR) spectroscopy. Treatment did not cause positive bulking efficiency and anti-swelling efficiency, because St/AA cannot diffuse into the cell walls due to its high molecular mass. The modulus of elasticity and rupture (MOE and MOR, respectively), and the surface hardness of the wood were improved by 24.4, 22.2, and 40.6%, respectively. Compression strength increased by 81.6 and 48.2% in radial and longitudinal directions, but the impact strength was hardly influenced by the treatment. In addition, the treated wood was slightly more hydrophobic than untreated controls as shown by reduced moisture content and water uptake. Accordingly, treatment with St/AA leads to mechanical reinforcement of wood and enhances its water resistance, and as a consequence, it has an application potential to improve the wood quality.

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