scholarly journals Iron-deficiency anemia and associated factors among preschool children in Diamantina, Minas Gerais, Brazil

2017 ◽  
Vol 30 (2) ◽  
pp. 185-196
Author(s):  
Luciana Neri NOBRE ◽  
Angelina do Carmo LESSA ◽  
Hilda Christiane de OLIVEIRA ◽  
Joel Alves LAMOUNIER ◽  
Sylvia do Carmo Castro FRANCISCHINI
Keyword(s):  
Preschool Children ◽  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Associated Factors ◽  
Maternal Education ◽  
Minas Gerais ◽  
Education Level ◽  
Deficiency Anemia ◽  
Iron Depletion ◽  
The City

ABSTRACT Objective: Study the prevalence of iron depletion and iron-deficiency anemia and their associated factors in preschool children. Methods: Cross-sectional study with five-year old preschool children from a birth cohort of the city of Diamantina, Minas Gerais state, Brazil. Socioeconomic, demographic, and dietary characteristics were obtained through a questionnaire administered to each child mother or guardian. Iron depletion (normal hemoglobin and low serum ferritin levels) and iron-deficiency anemia (hemoglobin level than 11g/dL) were detected after collecting 5mL of venous blood of preschool children. Poisson regression was used to identify the factors associated with iron depletion and iron-deficiency anemia. Results: A total of 228 preschool were evaluated, corresponding to 97.4% of the children from a cohort study followed-up up to the end of their first year of life. Iron depletion and iron-deficiency anemia were detected, respectively, in 15.9% and 18.9% of the preschool children evaluated. Iron depletion was not associated with any variable studied, while low maternal education level was associated with iron-deficiency anemia (PR=1.83; P=0.03). Conclusion: Iron-deficiency anemia is considered as a mild public health problem among 5-year old children in the city of Diamantina, Minas Gerais. Higher maternal education level was a protective factor against this deficiency, and therefore it is as an important marker for the occurrence of iron-deficiency anemia in the population studied.

Prevalence and associated factors for iron deficiency anemia among pregnant women in Fuyang, China

2021 ◽  
pp. 1-10
Author(s):  
Ningzhi Zhang ◽  
Li Mei ◽  
Min Li ◽  
Yanjun Zhang ◽  
Jinliang Xu ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Pregnant Women ◽  
Iron Deficiency Anemia ◽  
Associated Factors ◽  
Deficiency Anemia

Correct Assessment of Iron Depletion and Iron Deficiency Anemia

2006 ◽  
Vol 18 (2) ◽  
pp. 133-139 ◽  
Author(s):  
Mohammad R Naghii ◽  
Fouladi Abbasali Imam
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Deficiency Anemia ◽  
Iron Depletion

α-Thalassemia: Genotypic Profile Associated with Ethnicity and Hematological Differentiation of Iron Deficiency Anemia in the Region of Uberaba, Minas Gerais, Brazil

Hemoglobin ◽  
2015 ◽  
Vol 39 (4) ◽  
pp. 264-269 ◽  
Author(s):  
Renata A. Volpe de Souza ◽  
Aline Menezes Carlos ◽  
Bruna M. Bereta de Souza ◽  
Cibele Velloso Rodrigues ◽  
Gilberto de Araujo Pereira ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Minas Gerais ◽  
Deficiency Anemia ◽  
Genotypic Profile

scholarly journals Determinants of Iron Deficiency Anemia in a Cohort of Children Aged 6-71 Months Living in the Northeast of Minas Gerais, Brazil

PLoS ONE ◽  
2015 ◽  
Vol 10 (10) ◽  
pp. e0139555 ◽  
Author(s):  
Francisca Helena Calheiros Zanin ◽  
Camilo Adalton Mariano da Silva ◽  
Élido Bonomo ◽  
Romero Alves Teixeira ◽  
Cíntia Aparecida de Jesus Pereira ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Minas Gerais ◽  
Deficiency Anemia

Macrophage Iron, Hepcidin, and Atherosclerotic Plaque Stability

2007 ◽  
Vol 232 (8) ◽  
pp. 1014-1020 ◽  
Author(s):  
Jerome l. Sullivan
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Atherosclerotic Plaque ◽  
Animal Studies ◽  
Iron Concentration ◽  
Normal Subjects ◽  
Lesion Size ◽  
The Body ◽  
Deficiency Anemia ◽  
Iron Depletion

Hepcidin has emerged as the key hormone in the regulation of iron balance and recycling. Elevated levels increase iron in macrophages and inhibit gastrointestinal iron uptake. The physiology of hepcidin suggests an additional mechanism by which iron depletion could protect against atherosclerotic lesion progression. Without hepcidin, macrophages retain less iron. Very low hepcidin levels occur in iron deficiency anemia and also in homozygous hemochromatosis. There is defective retention of iron in macrophages in hemochromatosis and also evidently no increase in atherosclerosis in this disorder. In normal subjects with intact hepcidin responses, atherosclerotic plaque has been reported to have roughly an order of magnitude higher iron concentration than that in healthy arterial wall. Hepcidin may promote plaque destabilization by preventing iron mobilization from macrophages within atherosclerotic lesions; the absence of this mobilization may result in increased cellular iron loads, lipid peroxidation, and progression to foam cells. Marked downregulation of hepcidin (e.g., by induction of iron deficiency anemia) could accelerate iron loss from intralesional macrophages. It is proposed that the minimally proatherogenic level of hepcidin is near the low levels associated with iron deficiency anemia or homozygous hemochromatosis. Induced iron deficiency anemia intensely mobilizes macrophage iron throughout the body to support erythropoiesis. Macrophage iron in the interior of atherosclerotic plaques is not exempt from this process. Decreases in both intralesional iron and lesion size by systemic iron reduction have been shown in animal studies. It remains to be confirmed in humans that a period of systemic iron depletion can decrease lesion size and increase lesion stability as demonstrated in animal studies. The proposed effects of hepcidin and iron in plaque progression offer an explanation of the paradox of no increase in atherosclerosis in patients with hemochromatosis despite a key role of iron in atherogenesis in normal subjects.

scholarly journals Factors associated with the iron nutritional status of Brazilian children aged 4 to 7 years

2017 ◽  
Vol 30 (3) ◽  
pp. 345-355
Author(s):  
Hercílio Paulino ANDRÉ ◽  
Sarah Aparecida VIEIRA ◽  
Sylvia do Carmo Castro FRANCESCHINI ◽  
Andréia Queiroz RIBEIRO ◽  
Helen Hermana Miranda HERMSDORFF ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Nutritional Status ◽  
Maternal Education ◽  
Linear Regression Analysis ◽  
Public Health Problem ◽  
Minas Gerais ◽  
Factors Associated ◽  
The City ◽  
Brazilian Children ◽  
Height For Age

ABSTRACT Objective To evaluate factors associated with the iron nutritional status of Brazilian children aged 4 to 7 years in the city of Viçosa, Minas Gerais state, Brazil. Methods This is a cross-sectional study of 357 children aged 4-7 years who had been followed-up up for during their first six months of life by the Breastfeeding Support Program. Socioeconomic and demographic characteristics, feeding practices, nutritional status (height-for-age and body mass index-for-age), and serum ferritin and hemoglobin concentrations were evaluated. Multiple linear regression analysis was carried out to evaluate factors independently associated with iron nutritional status (hemoglobin and ferritin), considering α=0.05 as the significance level. Results The prevalence of anemia and iron deficiency was (34) 9.52% and (11) 11.00%, respectively. The factors independently associated with anemia were younger child age, low maternal education, low height-for-age Z-scores, and children of single and separated mothers or widows. Iron deficiency was associated with child younger age and consumption of chocolates and chocolate flavored milk. Conclusion The results obtained allow us to conclude that anemia among children 4-7 years of age is a public health problem in the city of Viçosa, Minas Gerais. Therefore, there is a need for intervention measures targeting children in this age group. These measures can be implemented through food and nutritional education by encouraging the consumption of iron-rich foods.

Influence of Inflammation on Assessing Iron-Deficiency Anemia in Cuban Preschool Children

MEDICC Review ◽  
2021 ◽  
Vol 23 (3-4) ◽  
Author(s):  
Gisela M. Pita-Rodríguez ◽  
Cristina Chávez-Chong ◽  
Brenda Lambert-Lamazares ◽  
Minerva Montero-Díaz ◽  
Rolando Selgas-Lizano ◽  
...  
Keyword(s):  
Preschool Children ◽  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Deficiency Anemia
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