scholarly journals Pediatric voice-related quality of life and acoustic analysis of voice: a study in schoolchildren

Revista CEFAC ◽  
2021 ◽  
Vol 23 (4) ◽  
Author(s):  
Suelene Cibelle Silva dos Reis ◽  
Giselle Frutuoso Nascimento ◽  
Zulina Souza de Lira ◽  
Adriana de Oliveira Camargo Gomes
Keyword(s):  
Quality Of Life ◽  
Fundamental Frequency ◽  
Acoustic Analysis ◽  
Positive Impact ◽  
The Self ◽  
Acoustic Parameters ◽  
Noise Rate ◽  
Related Quality ◽  
Research Population

ABSTRACT Purpose: to assess the self-reported voice-related quality of life of schoolchildren without voice complaints and correlate it to acoustic parameters of voice. Methods: the research population comprised 31 children, mean age 6.5 (±0.17) years. The children’s perception of their voice-related quality of life was verified with the Pediatric Voice-Related Quality of Life Survey, which has 10 closed-ended questions and three domains. The acoustic parameters assessed were fundamental frequency, jitter, shimmer, glottal-to-noise excitation ratio, and noise rate, besides the phonatory deviation diagram, based on the analysis of the emission of the sustained vowel /ɛ/ for 5 seconds. Results: all the children obtained scores close to 100% in the three domains of the Pediatric Voice-Related Quality of Life Survey. As for the acoustic parameters, most of them presented abnormal values in the phonatory deviation diagram and in shimmer. There was a difference between girls and boys only in fundamental frequency. Conclusion: the pediatric self-reported voice-related quality of life of the children studied had a positive impact, despite the acoustic changes found in the voices. There was no correlation between the pediatric voice-related quality of life and the acoustic parameters in voice in the group studied.

The Vietnamese Version of the Health-related Quality of Life Measure for Children with Epilepsy (CHEQOL-25): Reliability

MedPharmRes ◽  
2017 ◽  
Vol 1 (1) ◽  
pp. 9-14
Author(s):  
Tri Doan ◽  
Tuan Tran ◽  
Han Nguyen ◽  
◽  
◽  
...  
Keyword(s):  
Quality Of Life ◽  
Good Practice ◽  
The Self ◽  
Self Report ◽  
Health Related Quality ◽  
Life Measure ◽  
Related Quality ◽  
Health Related ◽  
Parent Proxy

Purpose: This study aimed to translate and culturally adapt the self-report and parent-proxy Health-Related Quality of Life Measure for Children with Epilepsy (CHEQOL-25) into Vietnamese and to evaluate their reliability. Methods: Both English versions of the self-report and parent-proxy CHEQOL-25 were translated and culturally adapted into Vietnamese by using the Principles of Good Practice for the Translation and Cultural Adaptation Process. The Vietnamese versions were scored by 77 epileptic patients, who aged 8–15 years, and their parents/caregivers at neurology outpatient clinic of Children Hospital No. 2 – Ho Chi Minh City. Reliability of the questionnaires was determined by using Cronbach’s coefficient α and intra-class correlation coefficient (ICC). Results: Both Vietnamese versions of the self-report and parent-proxy CHEQOL-25 were shown to be consistent with the English ones, easy to understand for Vietnamese children and parents. Thus, no further modification was required. Cronbach’s α coefficient for each subscale of the Vietnamese version of the self-report and parent-proxy CHEQOL-25 was 0.65 to 0.86 and 0.83 to 0.86, respectively. The ICC for each subscale of the self-report and parent-proxy CHEQOL-25 was in the range of 0.61 to 0.86 and 0.77 to 0.98, respectively. Conclusion: The Vietnamese version of the self-report and parent-proxy CHEQOL-25 were the first questionnaires about quality of life of epileptic children in Vietnam. This Vietnamese version was shown to be reliable to assess the quality of life of children with epilepsy aged 8–15 years.

scholarly journals REiNS: Patient Report of Hearing in Neurofibromatosis Type 2: Recommendations for Clinical Trials

Neurology ◽  
2021 ◽  
pp. 10.1212/WNL.0000000000012424
Author(s):  
Heather L. Thompson ◽  
Ann Blanton ◽  
Barbara Franklin ◽  
Vanessa L. Merker ◽  
Kevin H. Franck ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Clinical Trials ◽  
Neurofibromatosis Type ◽  
The Self ◽  
Self Assessment ◽  
Hearing Function ◽  
Patient Reported ◽  
Related Quality

Objective:To systematically evaluate published patient-reported outcome measures for the assessment of hearing function and hearing-related quality of life, and subsequently recommend measures selected by the Response Evaluation in Neurofibromatosis and Schwannomatosis International Collaboration (REiNS) as endpoints for clinical trials in Neurofibromatosis Type 2.Methods:The REiNS patient-reported outcomes working group systematically evaluated published patient-reported outcome measures of (1) hearing function and (2) hearing-related quality of life for individuals with hearing loss of various etiologies using previously published REiNS rating procedures. Ten measures of hearing functioning and 11 measures of hearing-related quality of life were reviewed. Measures were numerically scored and compared primarily on their participant characteristics (including participant age range and availability of normative data), item content, psychometric properties, and feasibility for use in clinical trials.Results:The Self-Assessment of Communication and the Self-Assessment of Communication-Adolescent were identified as most useful for adult and pediatric populations with NF2, respectively, for the measurement of both hearing function and hearing-related quality of life. Measures were selected for their strengths in participant characteristics, item content, psychometric properties, and feasibility for use in clinical trials.Conclusions:Currently, REiNS recommends the Self-Assessment of Communication adult and adolescent forms for the assessment of patient-reported hearing function and hearing-related quality of life for clinical trials for neurofibromatosis type 2. Further work is needed to demonstrate the utility of these measures in evaluating pharmacological and/or behavioral interventions.

scholarly journals Population norms of health-related quality of life in Moscow, Russia: the EQ-5D-5L-based survey

2020 ◽  
Author(s):  
Malwina Hołownia-Voloskova ◽  
Aleksei Tarbastaev ◽  
Dominik Golicki
Keyword(s):  
Quality Of Life ◽  
Positive Impact ◽  
Health State ◽  
Health Related Quality ◽  
Population Norms ◽  
Russian Paper ◽  
Related Quality ◽  
Health Related ◽  
Eq Vas

Abstract Purpose To develop population norms for the EQ-5D-5L questionnaire based on a representative sample of Moscow citizens. Methods We used quota sampling accounting for sex, age group and administrative district of residence. Respondents in randomly selected outdoor and indoor locations were surveyed with the official Russian paper-and-pencil version of the EQ-5D-5L questionnaire and a set of socio-demographic questions. We estimated four types of EQ-5D results: the distribution of limitations according to EQ-5D-5L dimensions, the perception of the health-related quality of life (HRQoL) with a visual analogue scale (EQ VAS), the unweighted score for a respondent’s health state (Level Sum Score, LSS) and the Russian health preferences-based weighted score (EQ index). In order to estimate the EQ-5D-5L index, we used a newly developed Russian EQ-5D-3L value set, together with EuroQol Group cross-over methodology. Results A total of 1020 respondents (18–93 years old) from the general Moscow adult population completed the EQ-5D-5L questionnaire. HRQoL domains with the largest number of identified health limitations were pain/discomfort (48.6%) and anxiety/depression (44.1%). Two hundred seventy-nine respondents (27.0%) did not report any health restrictions. The mean EQ VAS and EQ-5D-5L index were 74.1 (SD 17.3) and 0.907 (0.106) respectively. Multivariate analysis showed that female sex, advanced age and lack of access to the Internet had a negative influence on HRQoL, whereas residence in certain districts had a positive impact. Conclusions The study provides population norms of health-related quality of life in Moscow, measured according to the EQ-5D-5L questionnaire. These reference values can be used to optimise the effectiveness of resource allocation in healthcare.

Influence of executive functions on the self-reported health-related quality of life of children with ADHD

2020 ◽  
Vol 29 (5) ◽  
pp. 1183-1192
Author(s):  
Mona Céline Schwörer ◽  
Tilman Reinelt ◽  
Franz Petermann ◽  
Ulrike Petermann
Keyword(s):  
Quality Of Life ◽  
Executive Functions ◽  
The Self ◽  
Health Related Quality ◽  
Children With Adhd ◽  
Related Quality ◽  
Health Related ◽  
Reported Health

“No problem” health-related quality of life (HRQoL) in patients treated with regorafenib (Reg) for relapsed metastatic colorectal cancer (mCRC).

2021 ◽  
Vol 39 (15_suppl) ◽  
pp. e15593-e15593
Author(s):  
Yun Su ◽  
Helene Ostojic ◽  
Savina Jaeger
Keyword(s):  
Quality Of Life ◽  
Positive Impact ◽  
Self Care ◽  
Phase Iii ◽  
Correct Trial ◽  
Double Blind ◽  
Five Dimensions ◽  
Related Quality ◽  
Space Data

e15593 Background: REG has been shown to improve survival and delay time to quality of life deterioration over placebo (PBO) in two large randomized, double-blind, placebo-controlled multi-center phase III trials CORRECT and CONCUR for the treatment of relapsed mCRC. We report on findings of the five-dimensions of HRQoL in the two trials. Methods: The five key dimensions of HRQoL were captured in the CORRECT and CONCUR trials using EuroQol 5-Dimension questionnaire 3-level version (EQ-5D-3L). The 5 dimensions are mobility, self-care, usual activities, pain/discomfort, and anxiety/depression. Each dimension has 3 levels: no problems, some problems, severe problems. We calculated the proportion of intent-to-treat (ITT) patients reporting “no problems” (NP) in each of the 5 dimensions by cycle and arm of treatment in the two trials. Results: Detailed descriptions of the trials have been reported previously. Due to space, data below focuses on CORRECT. ITT patients included 760 total in the CORRECT trial, 2:1 randomized to receive REG (N=505) and PBO (N=255). At baseline (BL), 95% of the ITT patients completed the questionnaire (Table), and patients reported the highest percentage of NP in self-care (87%) and lowest in pain/discomfort (35%). EQ-5D completion rates decline with each cycle of treatment, as are the percentages reporting NP in each dimension. The declines however appeared much more rapid for PBO than for REG. Both completion rate and percentages of NP were somewhat higher for PBO than for REG at BL, this continued until only cycle 2 and reversed completely from cycle 3 onward showing increasingly diminished proportion of those on PBO able to complete the questionnaire and reporting NP in each dimension. The differences between arms became larger with each cycle beginning cycle 3. Findings were similar for CONCUR (not shown). Conclusions: REG appeared to enable patients to maintain their mobility, self-care, usual activity, being pain-free and anxiety-free as well as their ability to complete the EQ-5D questionnaire, at much higher rates than PBO. Those whose EQ-5D were no longer available were likely poor performers that discontinued due to progression, death, toxicity or other unfavorable factors associated with their treatments. For PBO, toxicity was unlikely the reason. These findings suggest REG has a positive impact on quality of survival, as well as on length of survival. Further confirmatory analyses are needed.[Table: see text]

Implications of Synkinesis in Unilateral Vocal Fold Paralysis

2017 ◽  
Vol 157 (6) ◽  
pp. 1017-1024 ◽  
Author(s):  
Yu-Cheng Pei ◽  
Wei-Han Chang ◽  
Hsiu-Feng Chuang ◽  
Chia-Fen Chang ◽  
Tuan-Jen Fang
Keyword(s):  
Quality Of Life ◽  
Vocal Fold ◽  
Acoustic Analysis ◽  
Medical Center ◽  
Vocal Fold Paralysis ◽  
Unilateral Vocal Fold Paralysis ◽  
Cricothyroid Muscle ◽  
Related Quality ◽  
The Impact

Objectives In patients with unilateral vocal fold paralysis (UVFP), laryngeal electromyography (LEMG) occasionally observes synkinesis in laryngeal muscles, a condition that could impair vocal fold mobility and voice control. This study aims to evaluate the impact of synkinesis on UVFP patients. Study Design A retrospective case-control study. Setting Medical center. Subjects and Methods Patients with UVFP onset >6 months were recruited (N = 104). The outcome measurements included LEMG, quantitative LEMG analysis of thyroarytenoid–lateral cricoarytenoid (TA-LCA) muscle complex, glottal gap measured by videolaryngostroboscopy, voice-related quality of life, and voice acoustic analysis. Results According to the LEMG analysis, 8 patients (8%) had synkinesis, and 96 (92%) did not. In the synkinesis group, TA-LCA turn frequency in the lesioned side was comparable to that in the healthy side ( P = .52). Patients in the synkinesis group had higher TA-LCA turn frequency ( P = .001), higher probability of cricothyroid muscle dysfunction ( P = .04), and better voice-related quality of life ( P = .01) but objective voice outcomes comparable to those in the nonsynkinesis group. Conclusions Patients with synkinesis will have near-complete restoration in TA-LCA turn frequency but still experience voice impairment, a finding that is compatible with the mechanism of aberrant reinnervation. However, patients with synkinesis have better disease-related quality of life than do those without synkinesis.

Acoustic analysis of tracheo-oesophageal versus oesophageal speech

1994 ◽  
Vol 108 (4) ◽  
pp. 325-328 ◽  
Author(s):  
F. Debruyne ◽  
P. Delaere ◽  
J. Wouters ◽  
P. Uwents
Keyword(s):  
Frequency Spectrum ◽  
Fundamental Frequency ◽  
Acoustic Analysis ◽  
Respiratory Drive ◽  
Spectral Slope ◽  
Acoustic Parameters ◽  
Vocal Quality ◽  
Vibratory Pattern ◽  
The Voice

AbstractIn order to evaluate the vocal quality of tracheo-oesophageal and oesophageal speech, several objective acoustic parameters were measured in the acoustic waveform (fundamental frequency, waveform perturbation) and in the frequency spectrum (harmonic prominence, spectral slope). Twelve patients using tracheo-oesophageal speech (with the Provox® valve) and 12 patients using oesophageal speech for at least two months, participated.The main results were that tracheo-oesophageal voices more often showed a detectable fundamental frequency, and that this fundamental frequency was fairly stable; there was also a tendency to more clearly defined harmonics in tracheo-oesophageal speech. This suggests a more regular vibratory pattern in the pharyngo-oesophageal segment, due to the more efficient respiratory drive in tracheo-oesophageal speech. So, a better quality of the voice can be expected, in addition to the longer phonation time and higher maximal intensity.

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