scholarly journals Skeletal maturation in individuals with Down's syndrome: Comparison between PGS curve, cervical vertebrae and bones of the hand and wrist

2014 ◽  
Vol 19 (4) ◽  
pp. 58-65 ◽  
Author(s):  
Glauber Carinhena ◽  
Danilo Furquim Siqueira ◽  
Eduardo Kazuo Sannomiya
Keyword(s):  
Cervical Vertebrae ◽  
Statistical Significance ◽  
Down's Syndrome ◽  
Down’S Syndrome ◽  
Skeletal Maturation ◽  
Growth Spurt ◽  
Pubertal Growth Spurt ◽  
Pubertal Growth ◽  
Ossification Centers ◽  
Level Of Agreement

INTRODUCTION: This study was conducted with the aim of adapting the methods developed by Martins and Sakima to assess skeletal maturation by cervical vertebrae in the pubertal growth spurt (PGS) curve. It also aimed to test the reliability and agreement between those methods and the method of hand and wrist radiograph when compared two by two and all together. METHODS: The sample comprised 72 radiographs, with 36 lateral radiographs of the head and 36 hand-wrist radiographs of 36 subjects with Down's syndrome (DS), 13 female and 23 male, aged between 8 years and 6 months and 18 years and 7 months, with an average age of 13 years and 10 months. RESULTS AND CONCLUSIONS: Results revealed that adapting the methods developed by Martins and Sakima to assess skeletal maturation by cervical vertebrae in the curve of PGS is practical and useful in determining the stage of growth and development of individuals. The stages of maturation evaluated by cervical vertebrae and ossification centers observed in radiographs of the hand and wrist were considered reliable, with excellent level of agreement between the methods by Hassel and Farman as well as Baccetti, Franchi and McNamara Jr and Martins and Sakima. Additionally, results revealed an agreement that ranged between reasonable to good for the three methods used to assess the skeletal maturation, showing statistical significance.

Assessment of Skeletal Maturation using Mandibular Second Molar Maturation Stages

2014 ◽  
Vol 39 (1) ◽  
pp. 79-84 ◽  
Author(s):  
S Goyal ◽  
S Goyal ◽  
N Gugnani
Keyword(s):  
Skeletal Maturity ◽  
Cervical Vertebrae ◽  
Skeletal Maturation ◽  
Growth Spurt ◽  
Pubertal Growth Spurt ◽  
Second Molar ◽  
Pubertal Growth ◽  
Lateral Cephalograms ◽  
Mandibular Second Molar ◽  
Pre Treatment

Objectives: To investigate the relationship between cervical vertebrae maturation and mandibular second molar calcification stages.Study design: The study was designed as a retrospective, descriptive and crosssectional research project. Pre-treatment lateral cephalograms and panoramic radiographs of 99 males and 110 females in the age range of 7 to 18 years 7 months were evaluated with Demirjian Index (DI) and cervical vertebrae maturation indicators (CVMI) of Hassel and Farman. A null hypothesis was proposed that there is no relation between CVMI and DI. Results: A highly significant association (Pearson's contingency coefficient 0.713 for males and 0.863 for females) was found between DI and CVMI. In males, the DI stage E corresponded to stage 2 of CVMI (pre–peak of pubertal growth spurt) and DI stages F and G corresponded to stages 3 and 4 of CVMI (peak of pubertal growth spurt). DI stage H was associated with stages 5 and 6 of CVMI (end of pubertal growth spurt). In females, the DI stages C, D corresponded to CVMI stages 1, 2; DI stages E, F with CVMI stages 3, 4; DI stages G, H with CVMI stages 5, 6. Conclusion: Mandibular second molar calcification stages can be used as indicators for assessment of skeletal maturity.

Mandibular Asymmetry and Antigonial Notching in Individuals with Unilateral Cleft Lip and Palate

2002 ◽  
Vol 39 (1) ◽  
pp. 30-35 ◽  
Author(s):  
Stephanos Kyrkanides ◽  
Liubov Richter
Keyword(s):  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Facial Asymmetry ◽  
Skeletal Maturation ◽  
Growth Spurt ◽  
Pubertal Growth Spurt ◽  
Panoramic Radiographs ◽  
Pubertal Growth ◽  
Mandibular Asymmetry ◽  
Orthodontic Patients

Objective To determine whether asymmetric antigonial notching is associated with the development of mandibular and lower facial asymmetry in individuals with unilateral cleft lip and palate (UCLP). Design Retrospective mixed-longitudinal investigation including UCLP and nonaffected orthodontic patients. Participants All (24) available patients with UCLP treated in our clinic with complete longitudinal records, and 72 skeletal maturation matched noncleft orthodontic patients that served as controls. Subject records included hand-wrist, panoramic, frontal, and 45° oblique cephalometric radiographs. Main outcome Measures The development of mandibular asymmetry, measured on oblique cephalometric radiographs, as well as lower facial asymmetry, measured on frontal cephalometric radiographs, was monitored in individuals with UCLP in relation to antigonial notching asymmetry, assessed on panoramic and oblique cephalometric radiographs. Results First, no statistical differences were found in antigonial notching asymmetry between patients with UCLP and noncleft controls. Second, antigonial notching asymmetry, observed on panoramic and oblique cephalometric radiographs, significantly correlated with the attendant development of mandibular and lower facial asymmetry in individuals with UCLP. Third, the development of mandibular and lower facial asymmetry at pubertal and post-pubertal growth spurt stages significantly correlated with antigonial notching asymmetry, measured on panoramic radiographs, at prepubertal and pubertal growth spurt stages, respectively. Conclusions The degree of antigonial notching noted on panoramic radiographs can be used as an early indicator of developing mandibular and lower facial asymmetry in individuals with UCLP.

Skeletal Asymmetries of the Nasomaxillary Complex in Noncleft and Postsurgical Unilateral Cleft Lip and Palate Individuals

1995 ◽  
Vol 32 (5) ◽  
pp. 428-433 ◽  
Author(s):  
Stephanos Kyrkanides ◽  
Ron Bellohusen ◽  
J. Daniel Subtelny
Keyword(s):  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Significant Degree ◽  
Skeletal Maturation ◽  
Growth Spurt ◽  
Pubertal Growth Spurt ◽  
Pubertal Growth ◽  
Anterior Nasal Spine ◽  
And Control ◽  
Skeletal Asymmetry

Asymmetries in the nasomaxillary skeleton are very common in individuals with unilateral cleft lip and palate. The purpose of this study was to retrospectively evaluate postsurgical asymmetries of the nasomaxillary skeleton in unilateral cleft lip and palate patients. Included in this study were 36 complete cleft lip and palate subjects, along with 36 noncleft (control) subjects. Skeletal asymmetry, deviations of the anterior nasal spine, and the premaxillary area were compared by chronologic age and skeletal maturation in cleft subjects and controls. Comparison between cleft and control cases was assessed. Results indicated that skeletal asymmetry in unilateral clefts and controls peaks during the pubertal growth spurt. The anterior nasal spine and nasal septum always tend to deviate toward the noncleft side of the nasal cavity, although individual variation exists. Cleft subjects were found to be more asymmetric than noncleft subjects to a statistically significant degree.

scholarly journals Relationship between dental calcification and skeletal maturation in a Peruvian sample

2017 ◽  
Vol 22 (3) ◽  
pp. 89-96 ◽  
Author(s):  
Rocío M. Lecca-Morales ◽  
Marcos J. Carruitero
Keyword(s):  
Cervical Vertebrae ◽  
Skeletal Maturation ◽  
Growth Spurt ◽  
Mandibular Growth ◽  
Exact Test ◽  
Second Molar ◽  
Pubertal Growth ◽  
Mandibular Molar ◽  
Maturation Stages ◽  
Mandibular Second Molar

ABSTRACT Objective: the objective of the study was to determine the relationship between dental calcification stages and skeletal maturation in a Peruvian sample. Methods: panoramic, cephalometric and carpal radiographs of 78 patients (34 girls and 44 boys) between 7 and 17 years old (9.90 ± 2.5 years) were evaluated. Stages of tooth calcification of the mandibular canine, first premolar, second premolar, and second molar and the skeletal maturation with a hand-wrist and a cervical vertebrae method were assessed. The relationships between the stages were assessed using Spearman’s correlation coefficient. Additionally, the associations of mandibular and pubertal growth peak stages with tooth calcification were evaluated by Fisher’s exact test. Results: all teeth showed positive and statistically significant correlations, the highest correlation was between the mandibular second molar calcification stages with hand-wrist maturation stages (r = 0.758, p < 0.001) and with vertebrae cervical maturation stages (r = 0.605, p < 0.001). The pubertal growth spurt was found in the G stage of calcification of the second mandibular molar, and the mandibular growth peak was found in the F stage of calcification of the second molar. Conclusion: there was a positive relationship between dental calcification stages and skeletal maturation stages by hand-wrist and cervical vertebrae methods in the sample studied. Dental calcification stages of the second mandibular molar showed the highest positive correlation with the hand-wrist and cervical vertebrae stages.

scholarly journals Duration of the pubertal growth spurt in patients with increased craniofacial growth component in sagittal and vertical planes—retrospective and cross-sectional study

2021 ◽  
Author(s):  
Agnieszka Szemraj-Folmer ◽  
Anna Wojtaszek-Słomińska ◽  
Bogna Racka-Pilszak ◽  
Małgorzata Kuc-Michalska
Keyword(s):  
Statistical Significance ◽  
Class I ◽  
Growth Spurt ◽  
Class Iii ◽  
High Angle ◽  
Pubertal Growth Spurt ◽  
Skeletal Class ◽  
Pubertal Growth ◽  
Age Related ◽  
Group I

Abstract Objectives The aim of the study is to assess the skeletal age at the onset and end of the pubertal growth spurt and determine its duration in four growth type groups: (1) normodivergent skeletal Class I (I N), (2) normodivergent skeletal Class III (III N), (3) high-angle skeletal Class III (III H) and (4) high-angle skeletal Class I (I H). Materials and methods Two hundred thirteen subjects were selected from 2163 examined files. The cervical vertebral maturation stage was recorded by means of Baccetti’s method. The sagittal and vertical skeletal relations were evaluated according to Steiner analysis with Kaminek’s modification. The duration of the pubertal growth spurt was calculated from the difference between the means of the chronological age related to CS3 and CS4 maturation stages. Results The shortest lasting pubertal growth spurt was observed in group I N (1.1), followed by group III N (1.6). Major differences between arithmetic means CS4-CS3 were seen in groups I H and III H (2.3 and 2.7, respectively). Conclusions The following tendency was observed in the duration of the pubertal growth spurt: I N < III N < I H < III H. This tendency has statistical significance only in high-angle patients in comparison with normodivergent skeletal Class I. Clinical relevance Knowledge on the longer pubertal growth spurt in high-angle patients compared to patients with normal anteroposterior and vertical relationships can be useful in the selection of an appropriate therapeutic method and a treatment time.

scholarly journals Serum DHEA-S levels could be used as a comparable diagnostic test to assess the pubertal growth spurt in dentofacial orthopedics

2020 ◽  
Vol 21 (1) ◽  
Author(s):  
V. Anusuya ◽  
Amit Nagar ◽  
Pradeep Tandon ◽  
G. K. Singh ◽  
Gyan Prakash Singh ◽  
...  
Keyword(s):  
Diagnostic Test ◽  
Growth Spurt ◽  
Pubertal Growth Spurt ◽  
Pubertal Growth ◽  
Dentofacial Orthopedics

Prepubertal urinary estrogen excretion and its relationship with pubertal timing

2010 ◽  
Vol 299 (6) ◽  
pp. E990-E997 ◽  
Author(s):  
Lijie Shi ◽  
Thomas Remer ◽  
Anette E. Buyken ◽  
Michaela F. Hartmann ◽  
Philipp Hoffmann ◽  
...  
Keyword(s):  
Pubertal Timing ◽  
Height Velocity ◽  
Breast Development ◽  
Growth Spurt ◽  
Age At Menarche ◽  
Healthy Children ◽  
Pubertal Growth Spurt ◽  
Peak Height Velocity ◽  
Pubertal Growth ◽  
Estrogen Production

Whether prepubertal estrogen production impacts on the timing of puberty is not clear. We aimed to investigate prepubertal 24-h estrogen excretion levels and their association with early and late pubertal markers. Daily urinary excretion rates of estrogens of 132 healthy children, who provided 24-h urine samples 1 and 2 yr before the start of the pubertal growth spurt [age at takeoff (ATO)], were quantified by stable isotope dilution/GC-MS. E-sum3 (estrone + estradiol + estriol) was used as a marker for potentially bioactive estrogen metabolites and E-sum5 (E-sum3 + 16-epiestriol + 16-ketoestradiol) for total estrogen production. Pubertal outcomes were ATO, age at peak height velocity (APHV), duration of pubertal growth acceleration (APHV-ATO), age at Tanner stage 2 for pubic hair (PH2), genital (G2, boys) and breast (B2, girls) development, and age at menarche. Prepubertal urinary estrogen excretions (E-sum3 and E-sum5) were not associated with ATO, APHV, and age at PH2 but with duration of pubertal growth acceleration ( P < 0.01) in both sexes. Girls with higher E-sum3 reached B2 0.9 yr ( P = 0.04) and menarche 0.3 yr earlier ( P = 0.04) than girls with lower E-sum3. E-sum3 was not associated with age at G2 in boys ( P = 0.6). For most pubertal variables, the associations with E-sum3 were stronger than with E-sum5. In conclusion, prepubertal estrogens may not be critical for the onset of the pubertal growth spurt but are correlated with its duration in both boys and girls. Prepubertal estrogen levels may already predict the timing of girls' menstruation and breast development but do not appear to affect sexual maturation in boys.

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