scholarly journals Cysticidal therapy: impact on seizure control in epilepsy associated with neurocysticercosis

2000 ◽  
Vol 58 (4) ◽  
pp. 1014-1020 ◽  
Author(s):  
ISABEL CRISTINA DOS SANTOS ◽  
ELIANE KOBAYASHI ◽  
TÂNIA MARCHIORI CARDOSO ◽  
CARLOS ALBERTO MANTOVANI GUERREIRO ◽  
FERNANDO CENDES
Keyword(s):  
Seizure Control ◽  
Partial Epilepsy ◽  
Resonance Imaging ◽  
Partial Seizures ◽  
Complex Partial Seizures ◽  
Protein Levels ◽  
Elevated Protein ◽  
Imaging Results ◽  
The Mean ◽  
Electroencephalogram Eeg

OBJECTIVE: To evaluate the clinical features and seizure control of epilepsy related to neurocysticercosis. METHOD: 18 patients with partial epilepsy and neurocysticercosis were treated with albendazol or praziquantel and followed from 3 months to 12 years. We analyzed results from the CSF exam, interictal electroencephalogram (EEG), head computerized tomography and/or magnetic resonance imaging. RESULTS: The patients' mean age was 36.4 years. The mean duration of epilepsy was 16 years. 83% patients had simple partial seizures ; 17% had complex partial seizures . All patients underwent routine EEGs: 62% had abnormalities and 38% were normal. A relationship was observed between focal EEG abnormality and the location of cyst in 28% of the patients. The CSF exams showed pleocytosis in 33% of the patients, and 28% had elevated protein levels. Only 22% of patients had positive titer for cysticercosis in the CSF. In all patients who had somatosensory and special sensory seizures there was a relationship between location of the cysts and seizure semiology (n=11). After cysticidal therapy, 83% patients had a significant improvement in controlling seizures. CONCLUSION: In this group, we found a predominance of simple partial seizures and a relationship between somatosensory and special sensory seizures and the location of the cysts. Cysticidal therapy was effective in controlling seizures in these patients and should be considered for patients with partial seizures and semiology related to cyst location.

scholarly journals The Anticonvulsant Effects of Vitamin E: A Further Evaluation

1992 ◽  
Vol 19 (2) ◽  
pp. 201-203 ◽  
Author(s):  
Sheldon L. Levy ◽  
W.M. Burnham ◽  
A. Bishai ◽  
Paul A. Hwang
Keyword(s):  
Vitamin E ◽  
Partial Epilepsy ◽  
Maximal Electroshock ◽  
Partial Seizures ◽  
Ferrous Chloride ◽  
Complex Partial Seizures ◽  
Complex Partial Epilepsy ◽  
Kindled Seizures ◽  
Standard Animal ◽  
Anticonvulsant Effects

ABSTRACT:Vitamin E (d-α-tocopherol) has proven to be a useful adjunct to anticonvulsant drugs in clinical studies. Improvement has occurred even in patients with complex partial seizures, which are often resistant to drug therapy. In animals, vitamin E is effective against ferrous chloride seizures, hyperbaric oxygen seizures and penicillin-induced seizures. It has failed, however, to show anticonvulsant effects in the standard animal models used for drug screening – the maximal electroshock and threshold pentylenetetrazol tests. The present experiments were designed to further explore the anti-epileptic actions of vitamin E in animals. Three models related to complex partial epilepsy were used: 1) the development of amygdala-kindled seizures; 2) the development of electrically-induced status in kindled animals; and 3) the development of kainic-acid seizures. Vitamin E failed to produce significant effects in any of the models.

Insular epilepsy masquerading as multifocal cortical epilepsy as proven by depth electrode

2010 ◽  
Vol 5 (4) ◽  
pp. 365-367 ◽  
Author(s):  
Michael R. Levitt ◽  
Jeffrey G. Ojemann ◽  
John Kuratani
Keyword(s):  
Seizure Control ◽  
Seizure Activity ◽  
Insular Cortex ◽  
Diagnosis And Treatment ◽  
Precise Localization ◽  
Partial Seizures ◽  
Complex Partial Seizures ◽  
Cortical Areas ◽  
Depth Electrodes ◽  
Depth Electrode

The insular cortex is an uncommon epileptogenic location from which complex partial seizures may arise. Seizure activity in insular epilepsy may mimic temporal, parietal, or other cortical areas. Semiology, electroencephalography, and even surface electrocorticography recordings may falsely localize other cortical foci, leading to inaccurate diagnosis and treatment. The use of insular depth electrodes allows more precise localization of seizure foci. The authors describe the case of a young girl with seizures falsely localized to the cortex, with foci arising from the insula, as proven by depth electrode recordings. Resection of the insula yielded seizure control.

Magnetic Resonance Imaging of Intractable Complex Partial Seizures: Pathologic and Electroencephalographic Correlation

Epilepsia ◽  
1991 ◽  
Vol 32 (4) ◽  
pp. 454-459 ◽  
Author(s):  
Christopher F. Dowd ◽  
William P. Dillon ◽  
Nicholas M. Barbara ◽  
Kenneth D. Laxer
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Resonance Imaging ◽  
Partial Seizures ◽  
Complex Partial Seizures

Complex visual hallucinations and occipital seizures

2007 ◽  
Vol 19 (6) ◽  
pp. 376-379
Author(s):  
Mark Walterfang ◽  
Raju Yerra ◽  
Francesco Gaillard ◽  
Terence O’Brien ◽  
Ramon Mocellin ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Visual System ◽  
Young Woman ◽  
Visual Hallucinations ◽  
Resonance Imaging ◽  
Partial Seizures ◽  
Complex Partial Seizures ◽  
Electrographic Seizure ◽  
Secondary Generalization

Background:We describe the presentation of a young woman with long-standing complex partial seizures with occasional secondary generalization, who presented with complex visual hallucinations (CVHs) and delusions.Methods:Routine biological workup including magnetic resonance imaging revealed an area of significant left-sided occipital gliosis. Video telemetry monitoring revealed a left occipital focus for the origin of the electrographic seizure discharge.Conclusion:CVHs occur in a range of organic states, including epilepsy, and can be understood in terms of the underpinning neuroanatomy and neurotransmitter systems of the visual system.

scholarly journals A pilot study on benign partial epilepsy in children with complex partial seizures

Seizure ◽  
2001 ◽  
Vol 10 (3) ◽  
pp. 194-196 ◽  
Author(s):  
Yoshiko Ishiguro ◽  
Akihisa Okumura ◽  
Kazushi Nomura ◽  
Kazuyoshi Watanabe ◽  
Tamiko Negoro ◽  
...  
Keyword(s):  
Pilot Study ◽  
Partial Epilepsy ◽  
Partial Seizures ◽  
Complex Partial Seizures
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