scholarly journals MOLECULAR IDENTIFICATION OF Bartonella henselae IN A SERONEGATIVE CAT SCRATCH DISEASE PATIENT WITH AIDS IN RIO DE JANEIRO, BRAZIL

2014 ◽  
Vol 56 (4) ◽  
pp. 363-365 ◽  
Author(s):  
Alexsandra R.m. Favacho ◽  
Isabelle Roger ◽  
Amanda K. Akemi ◽  
Adonai A. Pessoa JR. ◽  
Andrea G. Varon ◽  
...  
Keyword(s):  
Rio De Janeiro ◽  
Wide Spectrum ◽  
Bartonella Henselae ◽  
Disease Patient ◽  
Clinical Manifestations ◽  
Lymph Node Biopsy ◽  
Cat Scratch Disease ◽  
Chain Reaction ◽  
Node Biopsy ◽  
Polymerase Chain

Bartonella henselae is associated with a wide spectrum of clinical manifestations, including cat scratch disease, endocarditis and meningoencephalitis, in immunocompetent and immunocompromised patients. We report the first molecularly confirmed case of B. henselae infection in an AIDS patient in state of Rio de Janeiro, Brazil. Although DNA sequence of B. henselae has been detected by polymerase chain reaction in a lymph node biopsy, acute and convalescent sera were nonreactive.

scholarly journals Clinical Manifestations of Bartonella henselae Infection Among Children

2021 ◽  
Vol 41 (1) ◽  
pp. 8-14
Author(s):  
Ivana Valenčak-Ignjatić ◽  
Diana Didović ◽  
Branko Miše ◽  
Marija Gužvinec ◽  
Oktavija Đaković Rode ◽  
...  
Keyword(s):  
Polymerase Chain Reaction ◽  
Bartonella Henselae ◽  
Acute Infection ◽  
Clinical Manifestations ◽  
Unknown Origin ◽  
Immunofluorescence Assay ◽  
University Hospital ◽  
Chain Reaction ◽  
Mild Disease ◽  
Polymerase Chain

Objectives: The aim of this study was to analyze clinical manifestations, epidemiology and laboratory parameters of B. henselae infection among children treated at the University Hospital for Infectious Diseases “Dr. Fran Mihaljević”, Zagreb from January 2014 until June 2019. Materials and methods: We retrospectively analyzed the epidemiology, clinical and laboratory characteristics among children with positive indirect immunofluorescence assay for B. henselae IgM and IgG or positive B. henselae polymerase chain reaction from lymph node aspirate. Results: A total of 104 patients, 47 (45,1%) female and 57 (54,8%) male were enrolled. The median age was 9,7 (range, 1,1 to 17,3 years). A history of cat contact was present in 101 (97,1%) children. Acute infection was serologically confirmed in 87 (83,6%), in 5 (4,8%) with PCR while both methods were positive in 12 (11,5%) patients. The presentation on B. henselae infection were regional lymphadenopathy , disseminated disease, encephalopathy and fever of unknown origin. Suppurative inflammation was the most common complication in patients with lymphadenopathy 12/92 (13%). Full recovery was the most frequent outcome (96,1%). Conclusion lesion: B. henselae infection among children is usually a mild disease presented as regional lymphadenopathy. Serology and polymerase chain reaction are useful tests for diagnosis. Treatment duration and choice of therapy depend on clinical manifestation and developed complications.

scholarly journals Disseminated cat-scratch disease: a case report

2015 ◽  
Vol 22 (2) ◽  
pp. 229-231
Author(s):  
Faizul Islam Chowdhury ◽  
MA Kashem ◽  
Md Anwar Hossain ◽  
Imran Munadil Ahsan ◽  
Avijit Pandit ◽  
...  
Keyword(s):  
Bartonella Henselae ◽  
Cervical Lymphadenopathy ◽  
Lymph Node Biopsy ◽  
Cat Scratch Disease ◽  
Gram Negative ◽  
Systemic Involvement ◽  
Medical College ◽  
Negative Bacillus ◽  
Node Biopsy ◽  
Gram Negative Bacillus

Cat-scratch disease is an infectious disease caused by Bartonella henselae, a gram-negative bacillus. The disease is usually transmitted to the human being by cat scratches. Cat-scratch disease typically presents with painful regional lymphadenopathy. Systemic involvement is unusual. A 35 years old lady, came with the complaints of fever, abdominal pain along with nausea, anorexia & difficulties of swallowing for 6 months. She has painful cervical lymphadenopathy. Histopathology of her lymph node biopsy shows features of cat-scratch disease. DOI: http://dx.doi.org/10.3329/jdmc.v22i2.21550 J Dhaka Medical College, Vol. 22, No.2, October, 2013, Page 229-231

scholarly journals Detection of Bartonella henselae DNA Using Polymerase Chain Reaction Assay in Patient with Cat Scratch Disease

2003 ◽  
Vol 83 (1) ◽  
pp. 67-68 ◽  
Author(s):  
Hiroyuki Hara ◽  
Hiroyuki Hara ◽  
Hiroyuki Hara ◽  
Hiroyuki Hara ◽  
Hiroyuki Hara ◽  
...  
Keyword(s):  
Polymerase Chain Reaction ◽  
Polymerase Chain Reaction Assay ◽  
Bartonella Henselae ◽  
Cat Scratch Disease ◽  
Chain Reaction ◽  
Polymerase Chain

Aids/Opportunistic Infections

1999 ◽  
Vol 5 (S2) ◽  
pp. 1096-1097
Author(s):  
J. Guccion
Keyword(s):  
Opportunistic Infections ◽  
Infectious Agent ◽  
B Cell Lymphoma ◽  
Lymph Node Biopsy ◽  
Cat Scratch Disease ◽  
Tissue Sections ◽  
Vascular Walls ◽  
Node Biopsy ◽  
Polymerase Chain ◽  
Generalized Lymphadenopathy

Use of TEM in the diagnosis of opportunistic infections in AIDS patients is indicated in three situations. First, when an opportunistic infection is suspected, but an infectious agent is not visible in tissue sections studied by light microscopy (LM). This situation is illustrated by the following case.(1) A 33-year-old man with AIDS presented with fever, nightsweats, generalized lymphadenopathy, and a 30 lb. weight loss. An inguinal lymph node biopsy was performed. There was no consensus as to the diagnosis among the pathologists who studied H&E sections of the biopsy. An obscure infectious disease, a B-cell lymphoma with amyloid stroma, and possibly Hodgkin's disease were the major considerations. TEM study revealed unexpected clusters of small, pleomorphic, coccobacillary bacteria in vascular walls typical of cat scratch disease. These bacteria were later further identified by polymerase chain reaction as belonging to the genus Rochalimaea(now Bartonella), an important cause of cat scratch disease.

scholarly journals Abscess-forming lymphadenopathy and osteomyelitis in children with Bartonella henselae infection

2008 ◽  
Vol 57 (4) ◽  
pp. 519-524 ◽  
Author(s):  
Regina Ridder-Schröter ◽  
Aleander Marx ◽  
Meinrad Beer ◽  
Dennis Tappe ◽  
Hans-Wolfgang Kreth ◽  
...  
Keyword(s):  
Lymph Node ◽  
Fever Of Unknown Origin ◽  
Bartonella Henselae ◽  
Systemic Infection ◽  
Unknown Origin ◽  
Lymph Node Biopsy ◽  
Cat Scratch Disease ◽  
Node Biopsy ◽  
Systemic Complication ◽  
Draining Lymph Nodes

Bartonella henselae is the agent of cat-scratch disease (CSD), a chronic lymphadenopathy among children and adolescents. A systemic infection is very rare and most of these cases are found in patients with immunodeficiency. Here, cases involving four children of 6–12 years of age are reported. Three of the children had an abscess-forming lymphadenopathy and surrounding myositis in the clavicular region of the upper arm. The diagnosis was made serologically and, in one case, using eubacterial universal PCR. One child was treated with erythromycin for 10 days, the second received cefotaxime and flucloxacillin for 14 days and the third child was not treated with antibiotics. The fourth child had a different course: a significantly elevated signal intensity affecting the complete humerus was found in magnetic resonance imaging, consistent with osteomyelitis. A lymph node abscess was also found in the axilla. Diagnosis was established by indirect fluorescence assay and lymph node biopsy. Antibiotic therapy using clarithromycin, clindamycin and rifampicin was gradually successful. Immunodeficiency was excluded. All described lesions healed without residues. In immunocompetent patients, infection affects skin and draining lymph nodes; however, prolonged fever of unknown origin as in the fourth patient indicated a systemic complication of CSD.

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