scholarly journals Case report of subcutaneous entomophthoromycosis with retroperitoneal invasion

2005 ◽  
Vol 38 (4) ◽  
pp. 348-350 ◽  
Author(s):  
Leonora Maciel de Souza Vianna ◽  
Marcus Vinícius Guimarães de Lacerda ◽  
Mário Augusto Pinto de Moraes

The authors describe a case of entomophthoromycosis in a previously healthy patient, who presented with an abscess in the right buttock. After surgical drainage it evolved into a retroperitoneal tumor. The patient improved clinically after resection of the mass and ketoconazole treatment. The histopathological analysis showed the Splendore-Hoeppli phenomenon, suggesting Basidiobolus ranarum infection, a zygomycosis generally restricted to the subcutaneous tissue, with rare gastrointestinal involvement.

2022 ◽  
pp. 541-543
Author(s):  
Nidha Gaffoor ◽  
Hima Sree Edupuganti ◽  
Jessica Minal ◽  
Archana Shetty ◽  
Supriya T R ◽  
...  

Calcinosis cutis is an uncommon soft tissue lesion characterized by the deposition of calcium salts in the skin or subcutaneous tissue attributed to a wide variety of causes. We present a case of idiopathic calcinosis cutis in an adult male, who presented with a swelling in the right iliac region. Chalky white aspirate and amorphous basophilic granular material on microscopy suggestive of calcium deposits were noted. Histopathological examination of the excised mass coupled with appropriate clinical background led to the final diagnosis of idiopathic calcinosis cutis. We present this case with a complete diagnostic workup to undermine the importance of considering this lesion in the differential diagnoses of a subcutaneous hard lump in an otherwise healthy patient.


2019 ◽  
Vol 4 (7) ◽  
pp. 118-126
Author(s):  
Pedro Walisson Gomes Feitosa ◽  
Andrezza Lobo Rodrigues ◽  
Esther Barbosa Gonçalves Felix ◽  
Maria Stella Batista de Freitas Neta ◽  
Sávio Samuel Feitosa Machado

Although neuroendocrine neoplasms are relatively uncommon entities, the appendix is a site with relatively frequent emergence of this pathology and its precise diagnosis and clinical management have been a challenge for practitioners. This paper aims to present and discuss a case report of neuroendocrine neoplasia in the appendix of a patient with acute abdomen who underwent appendectomy. A 46-year-old man referred to the Emergency Department complaining of abdominal pain in the right iliac fossa and signs of peritoneal irritation. After diagnosis of acute appendicitis, the patient underwent appendectomy. In a macroscopic analysis, an area of 1.9 cm long, hardened, irregular and yellowish shapes was noted in the distal third of the appendix. Histopathological analysis showed neoplasia consisting of invasive islands of monotonous rounded epithelioid cells, large areas of necrosis, high mitotic activity, neural and angiolymphatic invasion and extension to adipose tissue compatible with invasion of the mesoappendix. Circumferential resection was compromised, suggesting the persistence of neoplasia in the patient even after the surgical approach, which would probably recommend the need for surgical approach. Therefore, the importance of sending collected materials for anatomopathological analysis is emphasized, since it helps in the clinical evaluation, in the etiological diagnosis, guides the medical conduct in the evolution of the case, as well as assisting in family mourning in cases of mortality.Keywords: Neuroendocrine tumor, Appendix, Histopathological analysis. 


1970 ◽  
Vol 5 (2) ◽  
pp. 139-147
Author(s):  
Paula Boson Trotta ◽  
Karen Guimarães Rosa ◽  
Luciano Martins Alves da Rosa Martins Alves da Rosa

RESUMOIntrodução: O Sarcoma Fibroblástico Mixoinflamatório (SFMI) é um tumor de partes moles de baixo grau, raro, que apresenta predileção equivalente em ambos os gêneros, sem sofrer influência de fatores genéticos ou ambientais. Apresenta sintomas inespecíficos, o que dificulta o diagnóstico. A dor está presente no diagnóstico em cerca de 17% dos pacientes. Outro fator que atrapalha o diagnóstico está na raridade do tumor e inabilidade técnica de detectá-lo. Casuística: Apresenta-se um caso de um paciente do sexo masculino, de 47 anos encaminhado ao ortopedista com tumoração em região distal do segundo quirodáctilo da mão direita. Após cirurgia de ressecção tumoral foi detectado um tecido que se originava na falange distal e tinha coloração amarelada e consistência densa, mesclado com o subcutâneo. Observou-se isquemia transitória na polpa digital da falange distal ainda durante a cirurgia. Posterior exame imuno-histoquímico revelou tratar-se de um Sarcoma Fibroblástico Mixoinflamatório. Após a cirurgia, o paciente retorna com necrose da polpa digital submetida a cirurgia. Foi realizada limpeza e debridamento do tecido necrótico. O paciente evoluiu bem com total epitelização da área cruenta. Conclusão: Foi concluído tratar-se de um sarcoma de difícil diagnóstico, porém de baixa metastatização e bom prognostico.Palavras-chave: Sarcoma, Isquemia, Necrose. ABSTRACTIntroduction: Myxoinflammatory Fibroblastic Sarcoma is a low-grade, rare tumor of soft parts that presents equivalent predilection for both genders  suffering no influence of genetic or enviormental factors. It has non-specific symptoms, making it difficult to diagnose. Pain appears in the diagnosis only in 17% of patients. Another factor that hinders the diagnosis is in the fewness numbers of patients that have it, and the technical inability to detect it. Case Report: This case report describes the case of a male patient, 47 years old, that referred to the orthopedist a tumor in the distal region of the second finger of the right hand. After tumor resection it was detected a tissue that originated in the distal phalanx and had a yellowish color and dense consistency, mixed with the subcutaneous tissue. It was observed transient ischemia in the digital pulp of the distal phalanx during surgery. Subsequent immunohistochemical examination revealed that it was Myxoinflammatory Fibroblastic Sarcoma. After the surgery, the patient returned with necrosis of the fingertip. Cleaning and debridement of necrotic tissue was performed. The patient developed a complete epithelialization of the wound area. Conclusion: The conclusion is that this is a sarcoma which is difficult to diagnose, but with low metastasis and good prognosis.Keywords: Sarcoma, Ischemia, Necrosis.


2021 ◽  
Vol 100 (4) ◽  

Introduction: Sebaceous carcinoma is a rare malignant tumor of the sebaceous glands. Sebaceous carcinoma occurs mainly in the head and neck region, rarely in trunk. Case report: We present a case report of 63-year-old patient, operated on for sebaceous carcinoma in the right breast area. The patient underwent radical surgery, removal of the tumor with the skin, subcutaneous tissue, and the large pectoral muscle. The patient is in good clinical condition eight months after the surgery. She is being constantly monitored and so far, there are neither signs of local recurrence nor tumor progression. Conclusion: Patients with rare tumors should be treated comprehensively with subsequent lifelong dispensarisation in specialized centers. Multidisciplinary medical teams are able to eruditely diagnose, recognize, treat and dispense patients.


2012 ◽  
Vol 2012 ◽  
pp. 1-9
Author(s):  
Rodrigo d'Eça Neves ◽  
Marcello Alberton Herdt ◽  
Felipe Barbieri Wohlgemuth ◽  
Jorge Bins Ely ◽  
Zulmar Antonio Accioli de Vasconcellos ◽  
...  

Objective. To evaluate the possible migration of polymethylmethacrylate after injections in various corporal compartments of Wistar rats. Methods. The experimental work consisted in the injection of PMMA in corporal compartments for later histopathological analysis of the locations of implants and of distant filtering organs. The dose applied in each implant was of 0.2 mL. The animals were divided into groups according to the location of the implant realized: group GB had intradermic injections in the glabella. Group SD had subdermal injections in dorsal subcutaneous tissue cells. Group IP had intraperitoneal injections in the abdomen. Group PD had intramuscular injections in the right rear leg. The rats were sacrificed 30 days after realization of the implants and tissue samples from the lung, liver, spleen, and kidney, and locations of implantation were removed for histopathological analysis. Results. Characteristic microspheres that were compatible with the presence of PMMA in any of the histological slides analyzed were not observed. One animal had an amorphous exogenous substance, with a histiocytic reaction. Twelve of the 16 lungs analyzed had locations of intraalveolar hemorrhaging. Two animals had nonspecific spleen alterations. Conclusion. The histopathological analysis of this study found no PMMA microspheres in any of the tissues analyzed.


2020 ◽  
Vol 48 (8) ◽  
pp. 030006052091481
Author(s):  
Lei Wang ◽  
Nian-Jun Ren ◽  
Hao Cai ◽  
Hao-Feng Cheng ◽  
Hai-Lin Zhang ◽  
...  

Solitary plasmacytoma (SP) of the skull is an uncommon clinical entity that is characterized by a localized proliferation of neoplastic monoclonal plasma cells. This case report describes a 50-year-old male that presented with a headache and an exophytic soft mass on the occiput. The diagnosis of SP was based on the pathological results and imaging examinations. The patient underwent occipital craniotomy, skull reconstruction and lower trapezius myocutaneous flap (LTMF) transplantation under general anaesthesia. The tumour was capsulized and extended to the subcutaneous and the subdural space through the dura mater with skull defects. The neoplasm of the occipital bone involved large areas of scalp and subcutaneous tissue, which resulted in a large postoperative scalp defect that was repaired using LTMF transplantation. All of the tumour was removed and the transplanted flap grew well. Follow-up at 5 months identified an aggressive mass lesion on the right frontal lobe. The patient received six cycles of the PAD chemotherapy regimen (bortezomib, doxorubicin and dexamethasone) and the lesion was significantly reduced. This case demonstrates that LTMF is an alternative approach for the repair of scalp and subcutaneous soft tissue defects caused by the excision of a large malignant tumour of the occipital region. Chemotherapy is the choice of treatment for neoplastic recurrence.


2017 ◽  
Vol 9 (1) ◽  
pp. 20-24 ◽  
Author(s):  
Fahad Alsaif ◽  
Amr M. Abduljabbar

Calcinosis cutis is a rare disorder characterized by the deposition of calcium in the skin and subcutaneous tissue. Unilateral idiopathic calcinosis cutis has only rarely been reported in the literature. Here, we report the case of a 7-year-old healthy girl who presented with multiple asymptomatic hard nodules on the right side of her body. Histopathological, radiological, and extensive blood investigations confirmed the diagnosis of unilateral idiopathic calcinosis cutis.


2017 ◽  
Vol 102 (1-2) ◽  
pp. 77-80
Author(s):  
David S. Sparks ◽  
Brandon M. Adams ◽  
Michael Wagels

Ventriculoperitoneal shunts (VPSs) are commonly used for the management of raised intraventricular pressure, especially in the context of hydrocephalus. Malignant invasion involving a VPS is an exceedingly rare association, only reported three times in the literature to date. We present the involvement of a VPS with a recurrent basal cell carcinoma (BCC), which has not been described previously. It was theorized that previously breached tissue planes associated with the VPS tract might facilitate local spread of the BCC. As such, this case represented an exceedingly rare association that has important conceptual implications for definitive surgical management. A 51-year-old paraplegic man with spina bifida and hydrocephalus, who had been immunosuppressed for 7 years following a renal transplantation, presented to our clinic with a recurrent BCC involving an inactive VPS in the right neck. Surgical management involved an excision of the scar with a peripheral margin of 1 cm, along with removal of the involved shunt tract and intraoperative pathologic assessment. Definitive histopathology revealed a focus of infiltrating sclerosing BCC involving the subcutaneous tissue and abutting the VPS. As the scope for synthetic materials in surgery continues to expand, so does the multitude of interesting complications that appear to arise from interactions between host tissue and foreign bodies. This case report describes a fascinating relationship between a recurrent BCC and a VPS, providing a guide for future management to ensure adequate surgical clearance. The case would be of interest to head/neck surgeons, neurosurgeons, and plastic surgeons.


2012 ◽  
Vol 69 (6) ◽  
pp. 531-535
Author(s):  
Dusan Skrbic ◽  
Goran Stojanovic ◽  
Djordje Povazan ◽  
Mirna Djuric ◽  
Zivka Eri

Introduction. Autofluorescence bronchoscopy (AFB) is a diagnostic procedure that is included in all diagnostic algorithms discovering precancerous lesions in the large airways. Case report. We presented a 71-year-old patient submitted to exploration due to prolonged cough. Both noninvasive and invasive pulmonary diagnostic management was carried out. On bronchoscopy, an endobronchial mass was detected in the apical bronchus. A positive endoscopy finding indicated AFB which disclosed a fluorescence alteration of the tumor mucosa and the former bronchoscopy site. Histopathological analysis of the catheter biopsy obtained samples from the right upper lobe confirmed fibrinous purulent pneumonia in organization. The applied treatment resulted in regression of both symptoms and the lesion in the right upper lobe. Due to a positive AFB finding, the patient was regularly observed over the following three years, having had three control AFB to monitor the initial finding. Conclusion. AFB may be utilized in the routine of everyday practice to assess the spread of the disease, as well as in the postsurgical and long-term follow-up of operated patients. The procedure may also be applied to enable an easier and more reliable observation of patients with suspicious endobronchial lesions, smokers with altered fluorescence of the bronchial mucosa, and chronic patients.


2021 ◽  
pp. 2172001
Author(s):  
Mahmood Ajawi ◽  
Irfan Abdulkareem ◽  
Abdullah H. Darwish ◽  
Iftikhar A. Mukhtar ◽  
Noora Iftikhar

Digital fibromyxoma is a rare soft tissue tumor with a propensity to grow in the digits of the hands and feet. While mostly asymptomatic, the tumors can grow and cause discomfort and eventually pain. It is a benign tumor, with treatment revolving around complete excision to prevent recurrence. In this case report, we discuss the case of a 11-year old boy presented with a swelling in the right ring finger that had been increasing in size for over a year. Despite the lack of pain or limitation of movement in the finger, the swelling caused concern to the patient and family due to cosmetic appearance. An excision biopsy with histopathological analysis of the tissue sample suggested the diagnosis of digital fibromyxoma. The high rate of recurrence is due to incomplete excision, and therefore regular follow up is recommended to monitor for recurrence.


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