scholarly journals Efficacy of florfenicol and intravenous fluid therapy for treatment of experimental salmonellosis in newborn calves

2010 ◽  
Vol 62 (3) ◽  
pp. 499-503
Author(s):  
D.G. Silva ◽  
P.R.L. Silva ◽  
J.J. Fagliari
Keyword(s):  
Experimental Infection ◽  
Fluid Therapy ◽  
Therapy Group ◽  
Clinical Signs ◽  
Intravenous Fluid ◽  
Control Group ◽  
Electrolyte Balance ◽  
Blood Concentrations ◽  
Intravenous Fluid Therapy ◽  
Salmonella Dublin

The efficacy of florfenicol associated or not to intravenous fluid therapy for treatment of Salmonella Dublin-infected calves was determined. Twenty-four healthy 10 to 15-day-old Holstein calves were randomly allotted into four groups, with six animals each: control (group 1); infected with 10(8)CFU Salmonella Dublin and not treated (group 2); infected with 10(8)CFU Salmonella Dublin and treated with florfenicol (group 3); and infected with 10(8)CFU Salmonella Dublin and treated with florfenicol associated to fluid therapy (group 4). All animals were submitted to physical examination just before inoculation and every 24 hours, during seven days after experimental infection. Rectal swabs and blood samples were collected for Salmonella Dublin isolation and pH and blood electrolytes determination. The experimental infection with Salmonella Dublin induced clinical signs of salmonellosis, such as diarrhea and fever, and caused reduction in blood concentrations of pH, sodium, potassium and chlorides. The treated calves showed good clinical recovery, and the group treated with antibiotic in combination to fluid therapy presented a faster and more efficient correction of the hydro-electrolyte balance.

scholarly journals Does Central Venous Oxygen Saturation-directed Fluid Therapy Affect Postoperative Morbidity after Colorectal Surgery?

2010 ◽  
Vol 113 (5) ◽  
pp. 1072-1080 ◽  
Author(s):  
Ib Jammer ◽  
Atle Ulvik ◽  
Christian Erichsen ◽  
Olav Lødemel ◽  
Gro Østgaard
Keyword(s):  
Oxygen Saturation ◽  
Fluid Therapy ◽  
Treatment Algorithm ◽  
Clinical Signs ◽  
Central Venous Oxygen Saturation ◽  
Intravenous Fluid ◽  
Control Group ◽  
Central Venous ◽  
Intensive Care Patients ◽  
Venous Oxygen Saturation

Background The optimal amount and method for monitoring intravenous fluid in surgical patients is unresolved. Central venous oxygen saturation (Scvo2) has been used to guide therapy and predict outcome in high-risk and intensive-care patients. The aim of this prospective, randomized trial was to compare the rate of postoperative complications in patients receiving fluid therapy guided by Scvo2 and those treated with a traditional effluent fluid scheme. Methods Patients undergoing open colorectal and lower intestinal surgery (n = 241) were randomized to the Scvo2 group or the control group. The Scvo2 group received perioperatively crystalloid infusion 100 ml/h. When Scvo2 was less than 75%, a bolus of 3 ml/kg hydroxyethyl starch was given. The bolus was repeated if Scvo2 increased by 1 percentage point or more. The control group was maintained with crystalloid 800 ml/h and given extra fluid if there were clinical signs of hypovolemia. The participating surgeon, unaware of the group allocation, registered complications within day 30. Results Until 8:00 am on the first postoperative day, the Scvo2 group had received 3,869 ± 992 ml (mean ± SD) intravenous fluid compared with 6,491 ± 1,649 ml in the control group. Increase in weight was 0.8 ± 1.8 kg and 2.5 ± 1.6 kg in the two groups, respectively. The postoperative complication rate was 42% in both groups. Conclusion Clinical outcomes among patients receiving Scvo2-guided perioperative fluid therapy were similar to those for patients treated with a traditional fluid regimen. Limitations in study design prevent full interpretation of these findings, and further large trials of this treatment algorithm are still required.

Confirmed 2,4-Dichlorophenoxyacetic Acid Toxicosis in a Dog

2010 ◽  
Vol 46 (1) ◽  
pp. 43-47 ◽  
Author(s):  
Annie V. Chen ◽  
Rodney S. Bagley ◽  
Patricia A. Talcott
Keyword(s):  
Clinical Outcomes ◽  
Fluid Therapy ◽  
Clinical Case ◽  
Clinical Signs ◽  
Intravenous Fluid ◽  
Dichlorophenoxyacetic Acid ◽  
Intact Male ◽  
Intravenous Fluid Therapy ◽  
2,4 Dichlorophenoxyacetic Acid ◽  
Serum And Urine

A 2-year-old, intact male Weimaraner was evaluated for episodic extensor rigidity and a stiff gait of 24 hours’ duration. Percussion of the proximal appendicular muscles with a reflex hammer resulted in formation of dimples consistent with myotonia. Electromyography identified myotonic potentials. Residues of 2,4-dichlorophenoxyacetic acid (2,4-D) were detected in both serum and urine. The dog was treated with intravenous fluid therapy for 36 hours, and clinical signs improved dramatically. Toxicosis with 2,4-D should be considered a differential for acquired myotonia in dogs with or without systemic signs. Exposed dogs with only clinical signs of myotonia can have good clinical outcomes. A confirmed clinical case of 2,4-D toxicosis in the dog has not previously been reported.

Goal-directed Fluid Therapy Does Not Reduce Primary Postoperative Ileus after Elective Laparoscopic Colorectal Surgery

2017 ◽  
Vol 127 (1) ◽  
pp. 36-49 ◽  
Author(s):  
Juan C. Gómez-Izquierdo ◽  
Alessandro Trainito ◽  
David Mirzakandov ◽  
Barry L. Stein ◽  
Sender Liberman ◽  
...  
Keyword(s):  
Colorectal Surgery ◽  
Fluid Therapy ◽  
Postoperative Ileus ◽  
Enhanced Recovery ◽  
Laparoscopic Colorectal Surgery ◽  
Enhanced Recovery After Surgery ◽  
Therapy Group ◽  
Control Group ◽  
Goal Directed Fluid Therapy ◽  
The Impact

Abstract Background Inadequate perioperative fluid therapy impairs gastrointestinal function. Studies primarily evaluating the impact of goal-directed fluid therapy on primary postoperative ileus are missing. The objective of this study was to determine whether goal-directed fluid therapy reduces the incidence of primary postoperative ileus after laparoscopic colorectal surgery within an Enhanced Recovery After Surgery program. Methods Randomized patient and assessor-blind controlled trial conducted in adult patients undergoing laparoscopic colorectal surgery within an Enhanced Recovery After Surgery program. Patients were assigned randomly to receive intraoperative goal-directed fluid therapy (goal-directed fluid therapy group) or fluid therapy based on traditional principles (control group). Primary postoperative ileus was the primary outcome. Results One hundred twenty-eight patients were included and analyzed (goal-directed fluid therapy group: n = 64; control group: n = 64). The incidence of primary postoperative ileus was 22% in the goal-directed fluid therapy and 22% in the control group (relative risk, 1; 95% CI, 0.5 to 1.9; P = 1.00). Intraoperatively, patients in the goal-directed fluid therapy group received less intravenous fluids (mainly less crystalloids) but a greater volume of colloids. The increase of stroke volume and cardiac output was more pronounced and sustained in the goal-directed fluid therapy group. Length of hospital stay, 30-day postoperative morbidity, and mortality were not different. Conclusions Intraoperative goal-directed fluid therapy compared with fluid therapy based on traditional principles does not reduce primary postoperative ileus in patients undergoing laparoscopic colorectal surgery in the context of an Enhanced Recovery After Surgery program. Its previously demonstrated benefits might have been offset by advancements in perioperative care.

scholarly journals Maji: A New Tool to Prevent Overhydration of Children Receiving Intravenous Fluid Therapy in Low-Resource Settings

2015 ◽  
Vol 92 (5) ◽  
pp. 1053-1058
Author(s):  
Kamal Shah ◽  
Taylor Vaughn ◽  
Rebecca Richards-Kortum ◽  
Bailey Flynn ◽  
Michael Pan ◽  
...  
Keyword(s):  
Fluid Therapy ◽  
Intravenous Fluid ◽  
Intravenous Fluid Therapy ◽  
Low Resource Settings ◽  
Low Resource

scholarly journals Comparison of the Effect of Oral and Intravenous Fluid Therapy on Women with Oligohydramnios

2008 ◽  
Vol 1 (1) ◽  
pp. 25-29 ◽  
Author(s):  
Nahid Lorzadeh ◽  
Sirous Kazemirad ◽  
Mina Lorzadeh ◽  
Sahid Najafi
Keyword(s):  
Fluid Therapy ◽  
Intravenous Fluid ◽  
Intravenous Fluid Therapy
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