scholarly journals Experimental model for low level laser therapy on ischemic random skin flap in rats

2006 ◽  
Vol 21 (4) ◽  
pp. 258-262 ◽  
Author(s):  
Rodrigo Paschoal Prado ◽  
Richard Eloin Liebano ◽  
Bernardo Hochman ◽  
Carlos Eduardo Pinfildi ◽  
Lydia Masako Ferreira

PURPOSE: To develop an experimental model to be used in the study of low level Laser therapy on viability of random skin flap in rats. METHODS: The sample was 24 Wistar-EPM rats. The random skin flap measured 10 x 4 cm and a plastic sheet was interposed between the flap and donor site. Group 1 (control) underwent sham irradiation with diode laser (830 nm). Group 2 was submitted to laser irradiation with diode laser (830 nm). The animals were submitted to Laser therapy with 36 J/cm² energy density (72 seconds) immediately after the surgery and on the four subsequent days. The probe was usually held in contact with the skin flap surface on a point at 2.5 cm cranial from the flap base. On the seventh postoperative day, the percentage of necrotic area was measured and calculated. RESULTS: Group 1 reached an average necrotic area of 48.86%, Group 2 - 23.14%. After the statistic analysis, compared with the control group, Group 2 showed a statistically significant increase in survival area (p<0.001). CONCLUSION: The experimental model proved to be reliable to be used in the study of effects of low level laser therapy in random skin flap in rats.

2012 ◽  
Vol 27 (2) ◽  
pp. 155-161 ◽  
Author(s):  
Cristiano Schiavinato Baldan ◽  
Amélia Pasqual Marques ◽  
Alessandra Maria Schiavinato ◽  
Raquel Aparecida Casarotto

PURPOSE: To investigate the effects of different low-level laser therapy (LLLT) doses on random skin flap rats. METHODS: Forty Wistar rats were randomly divided in four groups. The control group (CG) was not irradiated. The experimental groups were irradiated with a diode laser 670 nm with different energies per point: group 2 (G2) with 0.06 J; group 3 (G3) 0.15 J and group 4 (G4) 0.57 J. The three groups were irradiated in 12 equally distributed points in the cranial skin flap portion. They were submitted to the irradiation during the immediate, first and second postoperative days. The necrosis area was evaluated in the seventh postoperative day. RESULTS: The CG shows 49.35% of necrosis area in the skin flap; G2, 39.14%; G3, 47.01% and G4, 29.17% respectively. There was a significantly difference when G4 was compared with CG`s skin flap necrosis area. CONCLUSION: The low-level laser therapy diode 670 nm with 0.57 J energy per point increases the survival in randomic skin flap rats.


2021 ◽  
Vol 15 (1) ◽  
pp. 11-15
Author(s):  
Charu Mohan Marya ◽  
Jiksha Mehlawat ◽  
Ruchi Nagpal ◽  
Sakshi Kataria ◽  
Pratibha Taneja

Background. The present study aimed to assess and compare the pain perception and ulcer sizes before and after applying low-level laser therapy (LLLT) and Amlexanox + lidocaine. Methods. Twenty-six patients referring to the out-patient department of the institution and diagnosed with recurrent aphthous ulcers (RAU) were assigned to two groups to receive either LLLT or Amlexanox + lidocaine. In group 1, the patients were provided with amlexanox + lidocaine to apply topically four times daily. In group 2, the patients underwent LLLT with no tissue contact in inward circular motions for two cycles for 30 seconds. This study was registered in "the Clinical Trials Registry- India" (CTRI), with the registration number CTRI/2019/09/028222. The data were analyzed with SPSS 16. Results. The intergroup comparison was performed using Mann-Whitney U test, and intragroup comparisons were made using Wilcoxon’s signed-rank test. The level of significance was set at P<0.05. The results showed that pain perception and ulcer size were significantly lower in group 2 subjects than group 1 subjects (P<0.05). Conclusion. LLLT was more effective than amlexanox + lidocaine in the management of RAU. It is a cost-effective therapy for treating RAU.


2018 ◽  
Vol 33 (5) ◽  
pp. 1159-1169 ◽  
Author(s):  
Patricia Brassolatti ◽  
Ana Laura Martins de Andrade ◽  
Paulo Sérgio Bossini ◽  
Albaiza Nicoletti Otterço ◽  
Nivaldo Antônio Parizotto

2014 ◽  
Vol 30 (7) ◽  
pp. 1985-1990 ◽  
Author(s):  
Romildo Torres-Silva ◽  
Rodrigo Alvaro Brandão Lopes-Martins ◽  
Jan Magnus Bjordal ◽  
Lucio Frigo ◽  
Rachid Rahouadj ◽  
...  

Author(s):  
Suellen de Oliveira Veronez Silva ◽  
Lívia Assis ◽  
Paula Fernanda Gallani Martin Del Campo ◽  
Katherine Chuere Nunes Duarte ◽  
Flavia de Oliveira ◽  
...  

2015 ◽  
Vol 3 (4) ◽  
pp. 717-721 ◽  
Author(s):  
Hanaa M. Elshenawy ◽  
Amany Mohy Eldin ◽  
Mohamed Adel Abdelmonem

BACKGROUND: Oral lichen planus (OLP) is a chronic inflammatory disease of the oral mucosa of uncertain etiology.AIM: To evaluate the effect of using low level laser therapy (LLLT (970 nm Siro laser Advance) for the treatment of symptomatic (OLP).SUBJECTS AND METHODS: The present study was conducted on ten patients suffering from persistent oral lichen planus (OLP).Patients were treated with diode laser (970nm) for the symptomatic relief of pain and burning sensation. The patients were assessed before, during and after the completion of the laser treatment which was done twice weekly for two successive months with maximum of ten sessions. The assessment was performed using visual analogue scale (VAS) and clinical investigation for each patient.RESULTS: Detailed significant reduction in lesion size and showed complete remission of burning sensation and pain. No reported complications or therapy side effects were observed in any of the treated patients.CONCLUSION: Diode laser therapy seems to be an effective adjunctive treatment modality for relieving pain and clinical symptoms of OLP.


2018 ◽  
Vol 32 ◽  
Author(s):  
Hakan Arslan ◽  
Serhat Köseoğlu ◽  
Ezgi Doğanay Yildiz ◽  
Taner Arabaci ◽  
Levent Savran ◽  
...  

Materials ◽  
2019 ◽  
Vol 12 (13) ◽  
pp. 2187 ◽  
Author(s):  
Gaetano Isola ◽  
Marco Matarese ◽  
Francesco Briguglio ◽  
Vincenzo Grassia ◽  
Giacomo Picciolo ◽  
...  

The present study evaluated the effects of low-level laser therapy (LLLT) by means of a diode laser in accelerating orthodontic tooth movement (OTM). After extraction of the first upper premolars for orthodontic purpose, 82 maxillary canines which needed distalization were analyzed in 41 enrolled patients (21 males, 20 females, mean age 13.4 ± 2.1 years). On all experimental sites, an orthodontic force of 50/N was applied by a nickel-titanium (NiTi) closed coil spring (G&H, Franklin, IN, USA) in order to obtain the space closure. Using a split mouth randomized design, the test side was treated using a diode laser (Wiser Laser Doctor Smile, Brendola, Italy) operating at 810 nm wavelength in continuous wave mode at both the buccal and palatal side on three points/side (distal, medial and mesial) (1 W output power, continuous wave of 66.7 J/cm2, energy density of 8 J) at baseline and at 3, 7, and 14 days and every 15 days until the space closed. On the control side, the opposite selected canine was treated only using orthodontic traction. The primary outcome chosen was the overall time needed to complete the levelling and closing space, measured on a study cast. The secondary outcome chosen was the evaluation of pain levels related to tooth traction, using a Visual Analogue Scale (VAS), recorded at 3, 7, and 14 days after treatments. The mean space closures of the maxillary canines were comparable between groups [Test, 4.56 mm (95% CI 3.9–4.8); Control, 4.49 mm (95% CI 3.8–4.7), p = 0.456]. The laser group yielded less mean time [84.35 ± 12.34 days (95% CI 79.3–86)] to accomplish space closure compared to the control group [97.49 ± 11.44 days (91.7–102.3)] (p < 0.001). The test side showed a significant reduction in the average range of dental pain at 3 [Test, 5.41 (95% CI 5.1–5.6); Control, 7.23 (95% CI 6.9–7.6), p < 0.001], 7 [Test, 4.12 (95% CI 3.8–4.7); Control, 5.79 (95% CI 5.4–5.8), p < 0.001], and at 14 days [Test, 2.31 (95% CI 1.8–2.3); Control, 3.84 (95% CI 3.3–4.2), p < 0.001] after treatment (p < 0.001). This study demonstrates that the use of LLLT therapy was effective in accelerating tooth movement and reducing pain levels related to OTM.


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