scholarly journals Methods of inducing conditioned food aversion to Baccharis coridifolia (mio-mio) in cattle

2013 ◽  
Vol 43 (10) ◽  
pp. 1866-1871 ◽  
Author(s):  
Milton Begeres de Almeida ◽  
Ana Lucia Schild ◽  
James Pfister ◽  
Marcelo Pimentel ◽  
Karine Maciel Forster ◽  
...  
Keyword(s):  
Body Weight ◽  
Oral Administration ◽  
Low Doses ◽  
Food Aversion ◽  
Sufficient Time ◽  
Baccharis Coridifolia ◽  
Time To Learn ◽  
Conditioned Food Aversion

Three experiments were performed to determine the efficacy of various methods of averting naïve cattle to prevent Baccharis coridifolia poisoning: forced oral administration of 0.5g kg-1 body weight of fresh B. coridifolia; forced inhalation of the smoke from burning B. coridifolia and rubbing the plant on the animals' muzzles and mouths; and introducing the animals into paddocks with low invasion by B. coridifolia. Results demonstrated that cattle forced to ingest low doses become strongly averted if introduced into paddocks 23-26 hours after the aversion. In contrast, cattle introduced into the paddocks between 1-10 hours were not fully averted. Inhalation of B. coridifolia smoke, and rubbing the plant on the animals' muzzles and mouths were not efficient to induce an aversion. The introduction of cattle into paddocks with approximately 1% of B. coridifolia was efficient if the animals remained 5 months in the area, but not if they only remained for 60 hours, as cattle required sufficient time to learn to avoid the plant.

scholarly journals Conditioned food aversion to control poisoning by Ipomoea carnea subsp. fistulosa in goats

2014 ◽  
Vol 44 (7) ◽  
pp. 1240-1245 ◽  
Author(s):  
Carlos Alberto Oliveira Júnior ◽  
Gabriela Riet-Correa ◽  
Carla Tavares ◽  
Elda Souza ◽  
Valíria Duarte Cerqueira ◽  
...  
Keyword(s):  
Body Weight ◽  
Food Aversion ◽  
Ipomoea Carnea ◽  
Marajó Island ◽  
Toxic Plant ◽  
Conditioned Food Aversion

Ipomoea carnea is a toxic plant often ingested by livestock in Brazil. Three experiments were conducted to determine if conditioned food aversion was effective in reducing goats' consumption of I. carnea. In the first experiment, 10 mildly intoxicated goats that had been eating I. carnea were averted using LiCl (175 to 200mg kg-1 body weight). These intoxicated goats did not develop an aversion to I. carnea, demonstrating that the technique is not effective in goats that are already accustomed to consuming the plant. In the second experiment, 14 naïve goats were placed in a pasture with I. carnea, and averted after they ingested the plant. In this group the aversion persisted until the end of the experiment, 2 years and 8 months after the initial aversion. In another experiment, 20 goats were placed in a pasture with I. carnea, and after consuming the plant were averted with LiCl. The averted goats were transferred to Marajo Island and periodically observed over a 2 year period at 2-3 month intervals to determine if they were still averted. The averted goats did not ingest the plant while grazing in the pasture, whereas in 6 neighboring goat farms the prevalence of intoxication from I. carnea poisoning was estimated to be about 40%. These results demonstrated the efficacy of conditioned food aversion to avoid ingestion of I. carnea in formerly naïve goats that had only recently begun to ingest the plant.

scholarly journals Spontaneous and experimental poisoning of cattle by Palicourea aeneofusca in the region of Pernambuco and induction of conditioned food aversion

2015 ◽  
Vol 46 (1) ◽  
pp. 138-143 ◽  
Author(s):  
Luiz Bezerra de Brito ◽  
Raquel Feitosa Albuquerque ◽  
Brena Pessoa Rocha ◽  
Samuel Salgado Albuquerque ◽  
Stephen Tomas Lee ◽  
...  
Keyword(s):  
Body Weight ◽  
Single Dose ◽  
Lithium Chloride ◽  
Test Group ◽  
Aversive Conditioning ◽  
Feeding Tube ◽  
The Other ◽  
Control Group ◽  
Food Aversion ◽  
Conditioned Food Aversion

ABSTRACT: The objective of this study was to describe the epidemiological, clinical, and pathological aspects of Palicourea aeneofusca poisoning in cattle in the region of Pernambuco, Brazil and to determine if it is possible to induce food aversion by P. aeneofusca poisoning in cattle raised under extensive management conditions. To determine the occurrence of poisoning, 30 properties were visited in five municipalities of the region of Pernambuco. Three outbreaks of poisoning of cattle were monitored. To induce conditioned food aversion by the consumption of P. aeneofusca, 12 animals were randomly distributed into two groups of six animals each. Cattle were weighed and received green P. aeneofusca leaves in their trough at a dose of 35mg kg-1 body weight for spontaneous consumption. The control group (CG) animals received water (1ml kg-1 body weight) via a feeding tube after the first ingestion of the plant, while the other animals, constituting the aversion test group (ATG), underwent induced aversion with lithium chloride (LiCl - 175mg kg-1 body weight) via a feeding tube. For the ATG cattle, the aversion to P. aeneofusca induced by a single dose of LiCl persisted for 12 months. In contrast, the CG animals continued to consume the plant in all tests performed, indicating the absence of aversion. This study showed that aversive conditioning using LiCl was effective in preventing poisoning by P. aeneofusca for a period of at least 12 months.

scholarly journals Conditioned food aversion to control Palicourea aeneofusca poisoning

2014 ◽  
Vol 44 (7) ◽  
pp. 1246-1248 ◽  
Author(s):  
Murilo Duarte Oliveira ◽  
Franklin Riet-Correa ◽  
Genilson Barbosa da Silva ◽  
Walkleber dos Santos Pereira ◽  
Luis Flávio Souza Freire ◽  
...  
Keyword(s):  
Body Weight ◽  
Sudden Death ◽  
Lithium Chloride ◽  
Food Aversion ◽  
Green Leaves ◽  
Toxic Plant ◽  
Conditioned Food Aversion ◽  
Group 1

Palicourea aeneofusca contains sodium monofluoroacetate, which causes sudden death in ruminants when administered at doses of approximately 0.6g kg-1 of body weight (g kg-1). In this experiment two groups of 6 goats were used to determine the possibility to induce conditioned food aversion to P. aeneofusca. In group 1, 0.35g kg-1 of green leaves of the plant were given to six goats on days 1, 5, 10, 20, 30, 60, and 90 of the experiment. On the first day, all of the goats ingested the full amount of the plant and were treated immediately with 175mg kg-1 of lithium chloride (LiCl) through a ruminal tube. On day 5, only two goats ingested the plant, and they were treated with the same dose of LiCl. On days 10, 20, 30, 60, and 90, none of the goats ingested the plant. For another group of 6 goats, the leaves were given on days 1, 10, 20, 30, 60, and 90. All of the goats ingested the leaves on day 1 and received 1mL kg-1 body weight of water through a ruminal tube. All of these goats ingested the plant on days 10, 20, 30, 60, and 90. These results demonstrate that it is possible to induce conditioned food aversion to P. aeneofusca that persists for at least 90 days. Further experiments should be performed to determine the duration of the aversion and to induce aversion to other Palicourea species, particularly P. marcgravii, which is the most important toxic plant in Brazil.

scholarly journals Conditioned food aversion to Ipomoea carnea var. fistulosa induced by Baccharis coridifolia in goats

2013 ◽  
Vol 33 (8) ◽  
pp. 999-1003 ◽  
Author(s):  
Maria de Lourdes Adrien ◽  
Gabriela Riet-Correa ◽  
Carlos Alberto de Oliveira ◽  
James A. Pfister ◽  
Daniel Cook ◽  
...  
Keyword(s):  
Aversive Conditioning ◽  
Food Aversion ◽  
Oral Gavage ◽  
Ipomoea Carnea ◽  
Toxic Plants ◽  
Qualified Personnel ◽  
Group 2 ◽  
Baccharis Coridifolia ◽  
Conditioned Food Aversion ◽  
Group 1

Baccharis coridifolia is a plant that induces strong conditioned food aversion in ruminants. This research aimed to induce a conditioned food aversion to Ipomoea carnea var. fistulosa in goats, using B. coridifolia as an aversive agent, and to compare the aversion induced by this plant with the aversion induced by lithium chloride (LiCl). Thirteen goats were allotted into two groups: Group 1 with six goats was averted with 175mg/kg of body weight of LiCl and Group 2 with seven goats was averted with 0,25g/kg of bw of dried B. coridifolia. All goats were averted on day 1 after the ingestion of I. carnea. The aversion procedure with LiCl or B. coridifolia in goats from Groups 1 and 2, respectively, was repeated in those goats that again consumed the plant during tests on days 2, 3, and 7. The goats of both groups were challenged in pens on 23 and 38 days after the last day of aversion and challenged in the pasture on days 11, 15, 18, 20, 22, 25, 27 and 29 after the last day of aversion. After this period goats were challenged every 15 days on pasture until the 330º day after the last day of aversion (7th day). Two goats from Group 1 ingested I. carnea on the first day of the pasture challenge, 4 days after the last day of aversive conditioning in the pen. In addition, another goat in Group 1 started to consume the plant on day 18, and other two goats ate it on day 20. One goat in Group 1 that had never eaten I. carnea died on day 155. One goat from Group 2 started to ingest I. carnea on the first day of the pasture challenge, and a second goat started to consume this plant on day 182. At the end of the experiment, on day 330, the other five goats averted with B. coridifolia remained averted. These results suggest that B. coridifolia or an active compound from the plant could be used to induce aversion to toxic plants. Using B. coridifolia would be cheaper and, particularly in flocks with large number of animals, possibly easier than using LiCl, which requires the use of oral gavage and qualified personnel for its implementation.

Evaluation of Glucose and Lipid Lowering Activity of Arganimide A in Normal and Streptozotocin-Induced Diabetic Rats

2019 ◽  
Vol 19 (4) ◽  
pp. 503-510 ◽  
Author(s):  
Mohamed Eddouks ◽  
Farid Khallouki ◽  
Robert W. Owen ◽  
Morad Hebi ◽  
Remy Burcelin
Keyword(s):  
Body Weight ◽  
Blood Glucose ◽  
Oral Administration ◽  
Lipid Profile ◽  
Plasma Cholesterol ◽  
Diabetic Rats ◽  
Lipid Lowering ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Lowering Activity

Aims: Arganimide A (4,4-dihydroxy-3,3-imino-di-benzoic acid) is a compound belonging to a family of aminophenolics found in fruit of Argania spinosa. The purpose of this study was to investigate the glucose and lipid lowering activity of Arganimide A (ARG A). Methods: The effect of a single dose and daily oral administration of Arganimide A (ARG A) on blood glucose levels and plasma lipid profile was tested in normal and streptozotocin (STZ) diabetic rats at a dose of 2 mg/kg body weight. Results: Single oral administration of ARG A reduced blood glucose levels from 26.50±0.61 mmol/L to 14.27±0.73 mmol/L (p<0.0001) six hours after administration in STZ diabetic rats. Furthermore, blood glucose levels were decreased from 5.35±0.30 mmol/L to 3.57±0.17 mmol/L (p<0.0001) and from 26.50±0.61 mmol/L to 3.67±0.29 mmol/L (p<0.0001) in normal and STZ diabetic rats, respectively, after seven days of treatment. Moreover, no significant changes in body weight in normal and STZ rats were shown. According to the lipid profile, the plasma triglycerides levels were decreased significantly in diabetic rats after seven days of ARG treatment (p<0.05). Moreover, seven days of ARG A treatment decreased significantly the plasma cholesterol concentrations (p<0.001). Conclusion: ARG A possesses glucose and lipid-lowering activity in diabetic rats and this natural compound may be beneficial in the treatment of diabetes.

Conditioned food aversion reduces crow nest predation: An improved framework for CFA trials

2021 ◽  
Vol 60 ◽  
pp. 125970
Author(s):  
Angela J. Ferguson ◽  
Robert L. Thomson ◽  
Martha J. Nelson-Flower ◽  
Thomas P. Flower
Keyword(s):  
Nest Predation ◽  
Food Aversion ◽  
Conditioned Food Aversion

Processes of DNA Methylation Are Involved in the Mechanisms of Amnesia Induction and Conditioned Food Aversion Memory Reconsolidation

2014 ◽  
Vol 156 (4) ◽  
pp. 430-434 ◽  
Author(s):  
S. V. Solntseva ◽  
T. S. Filatova ◽  
P. V. Nikitin ◽  
D. V. Bredov ◽  
S. A. Kozyrev ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Memory Reconsolidation ◽  
Food Aversion ◽  
Conditioned Food Aversion

scholarly journals Perinatal exposure to low doses of bisphenol A affects body weight, patterns of estrous cyclicity, and plasma LH levels.

2001 ◽  
Vol 109 (7) ◽  
pp. 675-680 ◽  
Author(s):  
B S Rubin ◽  
M K Murray ◽  
D A Damassa ◽  
J C King ◽  
A M Soto
Keyword(s):  
Body Weight ◽  
Bisphenol A ◽  
Perinatal Exposure ◽  
Low Doses ◽  
Estrous Cyclicity

scholarly journals Effects of probiotics on loperamide-induced constipation in rats

2020 ◽  
Author(s):  
Takio Inatomi
Keyword(s):  
Body Weight ◽  
Fatty Acid ◽  
Oral Administration ◽  
Acid Concentration ◽  
Short Chain Fatty Acid ◽  
Phosphate Buffer Solution ◽  
Chain Fatty Acid ◽  
Short Chain ◽  
Fatty Acid Concentration ◽  
Sd Rats

AbstractConstipation, a common health problem, causes discomfort and affects quality of life. This study aimed to evaluate the potential effect of probiotics on loperamide (LP)-induced constipation in Sprague-Dawley (SD) rats, a well-established animal model of spastic constipation. In total, 100 male SD rats (age, 8 weeks; Japan SLC, Inc., Hamamatsu, Japan) were used in the experiments following a 12-day acclimatisation period. They were randomly divided into two treatment groups (groups 1 and 2) of 50 rats each. Spastic constipation was induced via oral administration of LP (3 mg/kg) for 6 days 1 hour before the administration of each test compound. Similarly, a probiotics solution (4 ml/kg body weight) was orally administered to the rats once a day for 6 days in group 2. In group 1, phosphate buffer solution was orally administered once a day for 6 days 1 hour after each LP administration. The changes in body weight, faecal parameters, short-chain fatty acid concentration in faeces, and faecal immunoglobulin (Ig)-A concentration were recorded. In the present study, the oral administration of probiotics improved faecal parameters, short-chain fatty acid concentration in faeces, and faecal IgA concentration. Our results indicate that probiotics increase the levels of intestinal short-chain fatty acids, especially butyric acid, thereby improving constipation and intestinal immunity.

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