N-Acetylneuraminic Acid Specific Lectin and Antibacterial Activity from the Red Alga Gracilaria canaliculata Sonder

2021 ◽  
Vol 23 (2) ◽  
pp. 169-182
Author(s):  
Le Dinh Hung ◽  
Vo Thi Dieu Trang
Keyword(s):  
Antibacterial Activity ◽  
Red Alga ◽  
Acetylneuraminic Acid

scholarly journals N-acetylneuraminic acid specific lectin and antibacterial activity from the red alga Gracilaria canaliculata Sonder

Algologia ◽  
2021 ◽  
Vol 31 (2) ◽  
pp. 126-140
Author(s):  
Le Dinh Hung ◽  
◽  
Vo Thi Dieu Trang ◽  
Keyword(s):  
Vibrio Parahaemolyticus ◽  
Pathogenic Bacteria ◽  
Antibacterial Agents ◽  
Aqueous Ethanol ◽  
Divalent Cations ◽  
Red Alga ◽  
Acetylneuraminic Acid ◽  
High Affinity ◽  
Sds Page ◽  
Wide Range

A new lectin from the marine red alga Gracilaria canaliculata (GCL) was isolated by a combination of aqueous ethanol extraction, ethanol precipitation, ion exchange and filtration chromatography. Lectin gave a single band with molecular mass of 22,000 Da in both non-reducing and reducing SDS-PAGE conditions, indicating that GCL is a monomeric protein. The hemagglutination activities of GCL were stable over a wide range of pH from 3 to 10, temperature up 60 oC and not affected by either the presence of EDTA or addition of divalent cations. Lectin GCL had high affinity for N-acetylneuraminic acid through interacting with the acetamido group at equatorial C2 position of these sugar residues, suggesting that GCL is specific for N-acetylneuraminic acid. Furthermore, GCL inhibited the growth of human and shrimp pathogenic bacteria, Staphylococcus aureus and Vibrio alginolyticus, although it did not affect the growth of Escherichia coli, Enterobacter cloace, Vibrio parahaemolyticus and V. harveyi. The red alga G. canaliculata may promise to be a source of valuable lectins for application as antibacterial agents.

New Bioactive Secondary Metabolites from Bornean Red Alga, Laurencia similis (Ceramiales)

2013 ◽  
Vol 8 (3) ◽  
pp. 1934578X1300800 ◽  
Author(s):  
Takashi Kamada ◽  
Charles Santhanaraju Vairappan
Keyword(s):  
Antibacterial Activity ◽  
Secondary Metabolites ◽  
Secondary Metabolite ◽  
Red Alga ◽  
Algal Population ◽  
Cytotoxic Effects ◽  
Antibiotic Resistant ◽  
Good Antibacterial Activity ◽  
Bioactive Secondary Metabolites ◽  
Red Algal

A Bornean red algal population of Laurencia simlis Nam et Saito was analyzed for its secondary metabolite composition. Seven compounds were identified: ent -1(10)-aristolen-9β-ol (1), (+)-aristolone (2), axinysone B (3), 9-aristolen-1α-ol (4), 2,3,5,6-tetrabromoindole (5), 1-methyl-2,3,5,6-tetrabromoindole (6), and 1-methyl-2,3,5-tribromoindole (7). Compound 1 was identified as a new optical isomer of 1(10)-aristolen-9β-ol. Compounds 1, 4 and 5 exhibited good antibacterial activity against antibiotic resistant clinical bacteria and cytotoxic effects against selected cancer cell lines.

Screening of Phytochemicals and Antibacterial Activity of Marine Red Alga Portieria hornemannii (Lyngbye) P. C. Silva

2017 ◽  
Vol 9 (3) ◽  
pp. 131 ◽  
Author(s):  
Subbiah Murugesan ◽  
Sundaresan Bhuvaneswari ◽  
U.S. Mahadeva Rao ◽  
Vajiravelu Sivamurugan
Keyword(s):  
Antibacterial Activity ◽  
Red Alga ◽  
Portieria Hornemannii

ChemInform Abstract: Structure and Antibacterial Activity of Brominated Diterpenes from the Red Alga Sphaerococcus coronopifolius.

ChemInform ◽  
2010 ◽  
Vol 41 (23) ◽  
pp. no-no
Author(s):  
Vangelis Smyrniotopoulos ◽  
Constantinos Vagias ◽  
Mukhlesur M. Rahman ◽  
Simon Gibbons ◽  
Vassilios Roussis
Keyword(s):  
Antibacterial Activity ◽  
Red Alga ◽  
Abstract Structure

scholarly journals Costatone C—A new halogenated monoterpene from the New Zealand red alga plocamium angustum

2020 ◽  
Author(s):  
Joe Bracegirdle ◽  
Z Sohail ◽  
Michael Fairhurst ◽  
Monica Gerth ◽  
Giuseppe Zuccarello ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Antibacterial Activity ◽  
New Zealand ◽  
Natural Product ◽  
Absolute Configuration ◽  
Red Algae ◽  
Red Alga ◽  
Product Distributions ◽  
Halogenated Monoterpenes ◽  
The Absolute

© 2019 by the authors Red algae of the genus Plocamium have been a rich source of halogenated monoterpenes. Herein, a new cyclic monoterpene, costatone C (7), was isolated from the extract of P. angustum collected in New Zealand, along with the previously reported (1E,5Z)-1,6-dichloro-2-methylhepta-1,5-dien-3-ol (8). Elucidation of the planar structure of 7 was achieved through conventional NMR and (−)-HR-APCI-MS techniques, and the absolute configuration by comparison of experimental and DFT-calculated ECD spectra. The absolute configuration of 8 was determined using Mosher’s method. Compound 7 showed mild antibacterial activity against Staphylococcus aureus and S. epidermidis. The state of Plocamium taxonomy and its implications upon natural product distributions, especially across samples from specimens collected in different countries, is also discussed.

scholarly journals Antibacterial Bromophenol from the Marine Red Alga Pterosiphonia complanata

2007 ◽  
Vol 2 (7) ◽  
pp. 1934578X0700200
Author(s):  
Samira Etahiri ◽  
Abdel Kebir El Kouria ◽  
Valérie Bultel-Poncé ◽  
Michèle Guyot ◽  
Omar Assobhei
Keyword(s):  
Staphylococcus Aureus ◽  
Antibacterial Activity ◽  
Minimum Inhibitory Concentration ◽  
Inhibitory Concentration ◽  
Methanol Extract ◽  
Red Alga ◽  
C Nmr

The dichloromethane/methanol extract of the red alga Pterosiphonia complanata exhibited antibacterial activity against many potentially pathogenic Gram (+) and Gram (-) bacteria. The compound responsible for this activity was isolated and identified, mainly on the basis of 1H and 13C NMR experiments, as the known 3,4,6-tribromo-5-methoxymethyl-benzene-1,2-diol. Its minimum inhibitory concentration against Staphylococcus aureus was 2.8 μg/mL (7 nM).

scholarly journals Costatone C—A New Halogenated Monoterpene from the New Zealand Red Alga Plocamium angustum

Marine Drugs ◽  
2019 ◽  
Vol 17 (7) ◽  
pp. 418 ◽  
Author(s):  
Joe Bracegirdle ◽  
Zaineb Sohail ◽  
Michael J. Fairhurst ◽  
Monica L. Gerth ◽  
Giuseppe C. Zuccarello ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Antibacterial Activity ◽  
New Zealand ◽  
Natural Product ◽  
Absolute Configuration ◽  
Red Algae ◽  
Red Alga ◽  
Product Distributions ◽  
Halogenated Monoterpenes ◽  
The Absolute

Red algae of the genus Plocamium have been a rich source of halogenated monoterpenes. Herein, a new cyclic monoterpene, costatone C (7), was isolated from the extract of P. angustum collected in New Zealand, along with the previously reported (1E,5Z)-1,6-dichloro-2-methylhepta-1,5-dien-3-ol (8). Elucidation of the planar structure of 7 was achieved through conventional NMR and (−)-HR-APCI-MS techniques, and the absolute configuration by comparison of experimental and DFT-calculated ECD spectra. The absolute configuration of 8 was determined using Mosher’s method. Compound 7 showed mild antibacterial activity against Staphylococcus aureus and S. epidermidis. The state of Plocamium taxonomy and its implications upon natural product distributions, especially across samples from specimens collected in different countries, is also discussed.

Antibacterial activity of Caulerpa racemosa against pathogenic bacteria promoting “ice-ice” disease in the red alga Gracilaria verrucosa

2019 ◽  
Vol 31 (5) ◽  
pp. 3201-3212 ◽  
Author(s):  
Elmi Nurhaidah Zainuddin ◽  
Hilal Anshary ◽  
Huyyirnah Huyyirnah ◽  
Ridha Hiola ◽  
Dolores V. Baxa
Keyword(s):  
Antibacterial Activity ◽  
Pathogenic Bacteria ◽  
Red Alga ◽  
Gracilaria Verrucosa ◽  
Caulerpa Racemosa

scholarly journals GREEN SYNTHESIS, CHARACTERIZATION OF SILVER NANOPARTICLES OF A MARINE RED ALGA SPYRIDIA FUSIFORMIS AND THEIR ANTIBACTERIAL ACTIVITY

2017 ◽  
Vol 9 (5) ◽  
pp. 192 ◽  
Author(s):  
Subbiah Murugesan ◽  
Sundaresan Bhuvaneswari ◽  
Vajiravelu Sivamurugan
Keyword(s):  
Silver Nanoparticles ◽  
Antibacterial Activity ◽  
Green Synthesis ◽  
Red Alga ◽  
Diffusion Method ◽  
Present System ◽  
X Ray Diffraction ◽  
Visible Spectroscopy ◽  
X Ray ◽  
Uv Visible

Objective: In the present system, the green synthesis of silver nanoparticles using marine the red alga Spyridia fusiformis and antibacterial activity was carried out.Methods: The seaweed extract was used for the synthesis of AgNPs at room temperature. The silver nanoparticles were characterized by using UV–Visible spectroscopy, Fourier transform infrared spectroscopy, transmission electron microscope and X-ray diffraction (XRD) techniques. The antibacterial activity of biosynthesized silver nanoparticles was carried out by disc diffusion method against pathogenic bacteria.Results: The UV-visible spectroscopy revealed surface plasmon resonance at 450 nm. The FT-IR measurements showed the possible functional groups responsible for the formation of nanoparticles. The X-ray diffraction analysis showed that the particles were crystalline in nature. TEM micrograph has shown the formation of silver nanoparticles with the size in the range of 5–50 nm. The silver nanoparticles synthesized from the S. fusiformis showed higher activity and proved their efficacy in controlling the pathogenic bacterial strains. The nanoparticles showed highest inhibition activity on K. pneumaniae and S. aureus up to 26 and 24±0.01 mm at 100 μg/ml of nanoparticles.Conclusion: The synthesised AgNPs have shown the best antibacterial activity against human pathogens E. coli, K. pneumoniae, S. aureus and P. aeruginosa. The above eco-friendly AgNPs synthesis procedure could be a viable solution for industrial applications in the future and therapeutic needs.

Sign in / Sign up

Export Citation Format

Share Document