Yield of Single- and Double-Strand Breaks and Nucleobase Lesions in Fully Hydrated Plasmid DNA Films Irradiated with High-LET Charged Particles

2012 ◽  
Vol 177 (5) ◽  
pp. 614-627 ◽  
Author(s):  
Takeshi Ushigome ◽  
Naoya Shikazono ◽  
Kentaro Fujii ◽  
Ritsuko Watanabe ◽  
Masao Suzuki ◽  
...  
Keyword(s):  
Plasmid Dna ◽  
Charged Particles ◽  
Double Strand Breaks ◽  
Strand Breaks ◽  
High Let ◽  
Dna Films

scholarly journals Fragmentation of Plasmid DNA Produced by Gamma Radiation: A Theoretical Approach

2012 ◽  
Vol 2012 ◽  
pp. 1-6
Author(s):  
R. A. S. Silva ◽  
J. D. T. Arruda-Neto ◽  
L. Nieto
Keyword(s):  
Plasmid Dna ◽  
Fragment Size ◽  
Power Laws ◽  
Double Strand Breaks ◽  
Strand Breaks ◽  
Starting Point ◽  
Dna Strands ◽  
High Let ◽  
Fragment Distribution ◽  
Dna Strand

Breaks in DNA, resulting in fragmented parts, can be produced by ionizing radiation which, in turn, is the starting point in the search for novel physical aspects of DNA strands. Double-strand breaks in particular cause disruption of the DNA strand, splitting it into several fragments. In order to study effects produced by radiation in plasmid DNA, a new simple mechanical model for this molecule is proposed. In this model, a Morse-like potential and a high-LET component are used to describe the DNA-radiation interaction. Two power laws, used to fit results of the model, suggest that, firstly, distribution of fragment size is nonextensive and, secondly, that a transition phase is present in the DNA fragment distribution pattern.

LET dependence of the yield of single-, double-strand breaks and base lesions in fully hydrated plasmid DNA films by4He2+ion irradiation

2008 ◽  
Vol 84 (1) ◽  
pp. 23-33 ◽  
Author(s):  
Ayumi Urushibara ◽  
Naoya Shikazono ◽  
Peter O'Neill ◽  
Kentaro Fujii ◽  
Seiichi Wada ◽  
...  
Keyword(s):  
Plasmid Dna ◽  
Ion Irradiation ◽  
Double Strand Breaks ◽  
Strand Breaks ◽  
Dna Films

scholarly journals Direct and Auger Electron-Induced, Single- and Double-Strand Breaks on Plasmid DNA Caused by 99mTc-Labeled Pyrene Derivatives and the Effect of Bonding Distance

PLoS ONE ◽  
2016 ◽  
Vol 11 (9) ◽  
pp. e0161973 ◽  
Author(s):  
Falco Reissig ◽  
Constantin Mamat ◽  
Joerg Steinbach ◽  
Hans-Juergen Pietzsch ◽  
Robert Freudenberg ◽  
...  
Keyword(s):  
Plasmid Dna ◽  
Auger Electron ◽  
Double Strand Breaks ◽  
Strand Breaks ◽  
Pyrene Derivatives

Spatial Distribution of Radiation-Induced Double-Strand Breaks in Plasmid DNA as Resolved by Atomic Force Microscopy

2005 ◽  
Vol 164 (6) ◽  
pp. 755-765 ◽  
Author(s):  
Dalong Pang ◽  
James E. Rodgers ◽  
Barry L. Berman ◽  
Sergey Chasovskikh ◽  
Anatoly Dritschilo
Keyword(s):  
Atomic Force Microscopy ◽  
Spatial Distribution ◽  
Plasmid Dna ◽  
Double Strand Breaks ◽  
Strand Breaks ◽  
Force Microscopy ◽  
Atomic Force ◽  
Radiation Induced

Effect of Hydration on the Induction of Strand Breaks and Base Lesions in Plasmid DNA Films by γ-Radiation

2002 ◽  
Vol 124 (30) ◽  
pp. 8859-8866 ◽  
Author(s):  
Akinari Yokoya ◽  
Siobhan M. T. Cunniffe ◽  
Peter O'Neill
Keyword(s):  
Plasmid Dna ◽  
Γ Radiation ◽  
Strand Breaks ◽  
Dna Films

Repair of double-strand breaks in plasmid DNA in the yeast Saccharomyces cerevisiae

1988 ◽  
Vol 213 (2-3) ◽  
pp. 421-424 ◽  
Author(s):  
Joseph R. Perera ◽  
Alexander V. Glasunov ◽  
Vadim M. Glaser ◽  
Alla V. Boreiko
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Plasmid Dna ◽  
Double Strand Breaks ◽  
Yeast Saccharomyces Cerevisiae ◽  
Strand Breaks

Clustered DNA Double-Strand Breaks and Neuroradiobiological Effects of Accelerated Charged Particles

2018 ◽  
Vol 15 (5) ◽  
pp. 551-561 ◽  
Author(s):  
A. V. Boreyko ◽  
A. N. Bugay ◽  
T. S. Bulanova ◽  
E. B. Dushanov ◽  
L. Jezkova ◽  
...  
Keyword(s):  
Charged Particles ◽  
Double Strand Breaks ◽  
Dna Double Strand Breaks ◽  
Strand Breaks
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