The presence of ferric and ferrous iron in the nonheme iron store of resident macrophages in different tissues and organs: histochemical demonstrations by the perfusion-Perls and -Turnbull methods in the rat

SummaryPlatelet aggregations were studied by a turbidimetric method in citrated human platelet-rich plasmas (PRP) in vitro. Human Clq inhibited the aggregations caused by collagens derived from different tissues and species. Clq was needed by weight in comparable quantities to collagen for neutralizing the aggregating effect. The dependence of the inhibitory reaction on the preincubation of platelets with Clq and the differences in the occurrence of aggregating substances in supernatants of PRP triggered with collagen in the presence or absence of Clq, confirmed that Clq exerts its effect by preventing fixation of collagen to platelets. In addition, the high specificity of the inhibitory action of Clq for collagen-induced platelet aggregation was demonstrated by results obtained for testing a variety of aggregating agents in combination with Clq and/or collagen.Since normal concentrations of Clq in the blood are in the range of inhibitory doses of Clq for collagen-induced platelet aggregations in vitro and upon activation of complement Clq is known to dissociate from Cl, it is proposed that Clq may participate in a highly specific manner in regulating platelet reactivity to collagen in vivo.

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PENDEKATAN EKSPLORASI RESERVOIR ONSHORE MELALUI PEMETAAN REMBESAN MIKRO HIDROKARBON DENGAN CITRA HIPERSPEKTRAL

Seminar Nasional Geomatika ◽

10.24895/sng.2018.3-0.1042 ◽

2019 ◽

Vol 3 ◽

pp. 1181

Author(s):

Muhamad Iqbal Januadi Putra

Keyword(s):

Ferrous Iron

Kapabilitas citra satelit hiperspektral yang memiliki keunggulan spektral sangat berpotensi untuk dimanfaatkan dalam eksplorasi keberadaan reservoir onshore. Kemampuan ini dilakukan melalui perekaman spektral fenomena rembesan mikro hidrokarbon yang menimbulkan ekspresi anomali spektral tanah dan menjadi kunci keberadaan sumber hidrokarbon. Dalam penelitian ini, Sub-Cekungan Jatibarang dipilih sebagai wilayah penelitian. Berdasarkan teori spektral rembesan mikro hidrokarbon, citra Hyperion dapat digunakan sebagai alat untuk mendeteksi keberadaan fenomena rembesan mikro hidrokarbon sebagai penduga keberadaan reservoir onshore karena memiliki spektrum panjang gelombang yang peka terhadap objek anomali hidrokarbon. Sehingga, penelitian ini bertujuan untuk mendeteksi area rembesan mikro hidrokarbon dengan citra Hyperion di Cekungan Jatibarang. Hydrocarbon Index (HI) yang memanfaatkan saluran 155 (1.699 nm), 158 (1.729 nm), dan 160 (1.749 nm) digunakan sebagai algoritma untuk medeteksi area rembesan mikro hidrokarbon di Sub-Cekungan Jatibarang. Gejala anomali alterasi kaolinite, ferrous iron dan gejala anomali vegetasi dengan indeks NDVI digunakan sebagai pembanding akurasi HI. Hasil penelitian ini menunjukkan adanya sebaran rembesan mikro hidrokarbon di wilayah Kecamatan Tukdana (Indramayu), Kecamatan Pasekan (Indramayu), dan Kecamatan Ligung (Majalengka). Area sebaran rembesan mikro hidrokarbon teraglomerasi pada wilayah pesisir utara Kecamatan Pasekan. Secara umum, keberadaan rembesan mikro hidrokarbon berkorelasi dengan tingkat anomali alterasi kaolinite, ferrous iron, dan anomali vegetasi.

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Synthesis and Breakdown of the Universal Precursors to Biological Metabolism Promoted by Ferrous Iron

10.26434/chemrxiv.7178930.v1 ◽

2018 ◽

Cited By ~ 1

Author(s):

Kamila B. Muchowska ◽

Sreejith Jayasree VARMA ◽

Joseph Moran

Keyword(s):

Amino Acids ◽

Chemical Reaction ◽

Metabolic Pathways ◽

Ferrous Iron ◽

Reaction Network ◽

Tca Cycle ◽

Chemical Reaction Network ◽

Metabolic Precursors ◽

Tca Cycle Intermediates

How core biological metabolism initiated and why it uses the intermediates, reactions and pathways that it does remains unclear. Life builds its molecules from CO2 and breaks them down to CO2 again through the intermediacy of just five metabolites that act as the hubs of biochemistry. Here, we describe a purely chemical reaction network promoted by Fe2+ in which aqueous pyruvate and glyoxylate, two products of abiotic CO2 reduction, build up nine of the eleven TCA cycle intermediates, including all five universal metabolic precursors. The intermediates simultaneously break down to CO2 in a life-like regime resembling biological anabolism and catabolism. Introduction of hydroxylamine and Fe0 produces four biological amino acids. The network significantly overlaps the TCA/rTCA and glyoxylate cycles and may represent a prebiotic precursor to these core metabolic pathways.

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