Risk factors for local recurrence of basal cell carcinoma and cutaneous squamous cell carcinoma of the middle third of the face: a 15-year retrospective analysis based on a single centre

2019 ◽  
Vol 29 (5) ◽  
pp. 490-499 ◽  
Author(s):  
Eleni Bourlidou ◽  
Kostas Vahtsevanos ◽  
Athanassios Kyrgidis ◽  
Ioannis Tilaveridis ◽  
Aikaterini Patsatsi ◽  
...  
Cancers ◽  
2021 ◽  
Vol 13 (14) ◽  
pp. 3402
Author(s):  
Eun Kyung Ko ◽  
Brian C. Capell

Recent evidence suggests that the disruption of gene expression by alterations in DNA, RNA, and histone methylation may be critical contributors to the pathogenesis of keratinocyte cancers (KCs), made up of basal cell carcinoma (BCC) and cutaneous squamous cell carcinoma (cSCC), which collectively outnumber all other human cancers combined. While it is clear that methylation modifiers are frequently dysregulated in KCs, the underlying molecular and mechanistic changes are only beginning to be understood. Intriguingly, it has recently emerged that there is extensive cross-talk amongst these distinct methylation processes. Here, we summarize and synthesize the latest findings in this space and highlight how these discoveries may uncover novel therapeutic approaches for these ubiquitous cancers.


2017 ◽  
Vol 77 (4) ◽  
pp. 713-718 ◽  
Author(s):  
Tina Bhutani ◽  
Michael Abrouk ◽  
Camelia S. Sima ◽  
Natalia Sadetsky ◽  
Jeannie Hou ◽  
...  

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