scholarly journals Effectiveness of the 6 × 6 Dieet® in Obese DMT2 Patients Effectiveness of a Very Low Carbohydrate Ketogenic Diet Compared to a Low Carbohydrate and Energy-Restricted Diet in Overweight/Obese Type 2 Diabetes Patients

2019 ◽  
Vol 5 (2) ◽  
Author(s):  
Govers E ◽  
Otten A ◽  
Schuiling B ◽  
Bouwman W ◽  
Lourens A ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Ketogenic Diet ◽  
Restricted Diet ◽  
Low Carbohydrate ◽  
Diabetes Patients

Effect of Low-Carbohydrate Diet on Metabolism in Type 2 Diabetes Patients with the Aid of Intelligent Administration of Insulin-Loaded Nanoparticle

2020 ◽  
Vol 12 (12) ◽  
pp. 1445-1451
Author(s):  
Xiaofan Zhang ◽  
Youyou Zhang ◽  
Lingjia Gu ◽  
Haiying Tao ◽  
Shuang Zhu
Keyword(s):  
Type 2 Diabetes ◽  
Glucose Solution ◽  
Fasting Blood Glucose ◽  
High Concentration ◽  
Carbohydrate Diet ◽  
Low Carbohydrate Diet ◽  
Low Carbohydrate ◽  
Hba1c Levels ◽  
Diabetes Patients

Nanoparticles play a major role in drug delivery. We investigated the effects of the intelligent administration of insulin-loaded nanoparticles (ILNP) when combined with a low-carbohydrate diet (LCD) on the metabolism of patients with type 2 diabetes. ILNP and smart vesicle polymers were developed, and their properties were studied in vitro. Further clinical trials were performed, during which body mass index (BMI), fasting blood glucose (FBG) levels, and glycated hemoglobin (HbA1c) levels were compared between type 2 diabetes patients on LCDs those on normal diets. The results demonstrated that ILNP resisted protease degradation due to steric hindrance, and remained relatively stable at a pH range of 5.0 to 7.4. The nanoparticle enteric-coated capsules resisted the gastric juice acidity (pH = 2.5) and ensured the stable embedding of the insulin. The insulin was then released at a slightly higher pH (pH = 6.6), which mimicked the small intestine. Smart vesicle polymers further embedded the insulin and glucose oxidase simultaneously in nano polymer compounds, which allowed for a dose-dependent response to the concentration of glucose. Thus, the insulin was not released in a low-concentration glucose solution, but rather in a high-concentration glucose solution. Based on these results, we concluded that the clinical trial results showed that the intelligent administration of ILNP combined with a LCD reduced BMI, FBG, and HbA1c levels in patients with type 2 diabetes.

Low-carbohydrate diet by staple change attenuates postprandial GIP and CPR levels in type 2 diabetes patients

2019 ◽  
Vol 33 (11) ◽  
pp. 107415 ◽  
Author(s):  
Mizuho Kondo-Ando ◽  
Yusuke Seino ◽  
Risa Morikawa ◽  
Kana Negi ◽  
Hidechika Todoroki ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Carbohydrate Diet ◽  
Low Carbohydrate Diet ◽  
Low Carbohydrate ◽  
Diabetes Patients

scholarly journals A low-carbohydrate, ketogenic diet to treat type 2 diabetes

2005 ◽  
Vol 2 (1) ◽  
Author(s):  
William S Yancy ◽  
Marjorie Foy ◽  
Allison M Chalecki ◽  
Mary C Vernon ◽  
Eric C Westman
Keyword(s):  
Type 2 Diabetes ◽  
Ketogenic Diet ◽  
Low Carbohydrate

A Pilot Trial of a Low-Carbohydrate, Ketogenic Diet in Patients with Type 2 Diabetes

2003 ◽  
Vol 1 (3) ◽  
pp. 239-243 ◽  
Author(s):  
William S. Yancy ◽  
Mary C. Vernon ◽  
Eric C. Westman
Keyword(s):  
Type 2 Diabetes ◽  
Ketogenic Diet ◽  
Pilot Trial ◽  
Low Carbohydrate

scholarly journals Revealing the molecular relationship between type 2 diabetes and the metabolic changes induced by a very-low-carbohydrate low-fat ketogenic diet

2010 ◽  
Vol 7 (1) ◽  
pp. 88 ◽  
Author(s):  
Judith Farrés ◽  
Albert Pujol ◽  
Mireia Coma ◽  
Jose Ruiz ◽  
Jordi Naval ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Ketogenic Diet ◽  
Metabolic Changes ◽  
Low Fat ◽  
Low Carbohydrate

Effect of low-calorie versus low-carbohydrate ketogenic diet in type 2 diabetes

Nutrition ◽  
2012 ◽  
Vol 28 (10) ◽  
pp. 1016-1021 ◽  
Author(s):  
Talib A. Hussain ◽  
Thazhumpal C. Mathew ◽  
Ali A. Dashti ◽  
Sami Asfar ◽  
Naji Al-Zaid ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Ketogenic Diet ◽  
Low Calorie ◽  
Low Carbohydrate
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