Title 1. Purchase, exchange (§§ 433–480)

2020 ◽  
pp. 732-834
Keyword(s):  
2021 ◽  
pp. 089719002110150
Author(s):  
Francisco Ibarra

Study Objective: Summarize the studies evaluating the use of 4-factor prothrombin complex concentrates in the management of apixaban and rivaroxaban associated intracranial hemorrhages. Methods: A PubMed literature search was conducted for articles published between 2013 and 2020 which contained the following terms in their title: (1) apixaban, rivaroxaban, or factor Xa inhibitor*, and (2) prothrombin complex concentrate*. Results: Eighteen observational studies were included. When a ∼25 units/kg (range: 25-26.9 units/kg) non-activated 4 factor prothrombin complex concentrate dose was administered, the hemostatic effectiveness rates were ≥ 79% in 2/4 studies that utilized the Sarode et al criteria, in comparison to 4/5 studies that administered a 50 units/kg dose. The mortality rates were < 20% in 7/9 studies with hemostatic effectiveness rates ≥ 79%. Mortality rates were lower in the studies demonstrating higher hemostatic effectiveness rates and including patients with higher Glasgow coma scale scores and lower intracerebral hemorrhage volumes. Overall, the thromboembolic event rates were 0-18%, with 16/18 studies demonstrating rates ≤ 10%. The thromboembolic event rates were not dose or agent dependent. Conclusion: Rates of hemostatic effectiveness were influenced by the definition of hemostatic effectiveness, dose administered, and patient severity. Studies suggest that higher doses may result in higher hemostatic effectiveness rates without increasing the risk of experiencing a thromboembolic event. This review may be used by providers to modify or validate their reversal strategy approach until well designed studies are available.


2019 ◽  
Vol 1 (1) ◽  
Author(s):  
Qian Wang ◽  
◽  
Laura Lewis ◽  

This study aims to explore preservice teachers' motivations to teach at Title I schools as well as whether their motivations differ based on how far they are in their teacher education program. A total of 128 preservice teachers from two groups with different numbers of field experiences were surveyed. Preservice teachers cited extrinsic, altruistic, intrinsic, and past learning experiences as main reasons motivated them wanting to teach at Title I schools upon graduation. Their motivations might change due to the influences from professional training and social experiences. It was also found that in both groups there were many preservice teachers undecided whether they wanted to teach at Title I schools or not. Implications for research and practice are discussed.


Author(s):  
Aubrey Statti

This chapter seeks to present an example of technologically-advanced curriculum through LATIC (learner-active, technology-infused classrooms). This study aimed to explore the specific application of LATIC curriculum in a 3rd grade Title 1 classroom in Southwest Florida. The research focused on 1) the intended and achieved learning outcomes of the curriculum, 2) student engagement with their peers, teacher, and technology, and 3) experienced successes as well as any challenges faced during the LATIC implementation process. Further, the purpose of this research was to experience the day to day functions of a LATIC in order to evaluate its appropriateness for learners of varying educational levels and backgrounds. Through the case study methodology, the researcher utilized classroom observations, interviews with the teacher, and an analysis of classroom documents and visual materials as a means to understand both the role of the students and of the teacher in a LATIC environment.


Author(s):  
Tobias Lock
Keyword(s):  
Title I ◽  
Title 1 ◽  

The rights guaranteed under this Title relate to the preservation and protection of human dignity. The concept of dignity does not serve merely as the basis for the articles that form part of this Title 1, but has been recognized as a foundation for human rights more generally, including, in particular, equality and anti-discrimination rights.


Author(s):  
Consuelo Carrasco García

A poetic sale. Horace, Epistula 2.2.
Starting from the analysis of a poem by Horace, I have tried to highlight the image of the Law that was held by Roman society in the first century BC, that is, both by the poet and by the public that he wanted to entertain with his works. He chose a legal topic as the theme of his narrative – the responsibility for hidden defects in the contract of sale –; he applied the Roman legal lexicon with total precision and, more specifically, he showed that he was aware of the debate about the case-law related to the Edict by which the magistrates regulated the sale of slaves in the public markets. This is apparent from a comparison of the poem with book 21, title 1 of Justinian’s Digest concerning the Edict of the curule aediles and with documents from legal practice (testatio) that record the agreement of the will of the parties. A study of this kind, moreover, also contributes to a better understanding of poetic composition.



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