The peculiar clinical features of different types of acquired cholesteatoma of the middle ear

An animal model for retraction pocket (primary acquired) cholesteatoma is presented. Bilateral eustachian tube obstruction by electrocauterization of the nasopharyngeal portion was performed in 16 Mongolian gerbils. Animals were killed at 2, 4, 8, and 16 weeks. At 2 weeks all animals had bilateral serous effusions and retracted tympanic membranes. At 4 weeks, four of eight ears had middle ear fluid, retractions, and cholesteatomas. After 8 weeks, five of eight ears had middle ear effusions, and four of these had cholesteatomas; one ear had total atelectasis with a cholesteatoma filling the bulla. By 16 weeks, six of eight ears had developed cholesteatomas. Some animals did not develop effusion or retraction because of failure or recanalization of eustachian tube obstruction. This study provides experimental evidence that aural cholesteatomas may arise by retraction of the tympanic membrane.

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Otorrhoea in children with middle ear. ventilation tubes: a comparison of different types of tubes

Clinical Otolaryngology ◽

10.1111/j.1365-2273.1987.tb00216.x ◽

1987 ◽

Vol 12 (5) ◽

pp. 357-360 ◽

Cited By ~ 22

Author(s):

R. W. T. SLACK ◽

J. M. GARDNER ◽

C. CHATFIELD

Keyword(s):

Middle Ear ◽

Different Types ◽

Middle Ear Ventilation ◽

Ventilation Tubes

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Hearing preservation despite labyrinthectomy for resection of giant cholesteatoma with middle fossa extension

The Journal of Laryngology & Otology ◽

10.1017/s0022215100140812 ◽

1998 ◽

Vol 112 (5) ◽

pp. 472-475 ◽

Cited By ~ 5

Author(s):

F. Rapado ◽

N. Fergie ◽

R. T. Ramsden

Keyword(s):

Middle Ear ◽

Bone Conduction ◽

Mass Effect ◽

Hearing Preservation ◽

Middle Cranial Fossa ◽

Middle Fossa ◽

Bone Conduction Threshold ◽

Acquired Cholesteatoma ◽

Cranial Fossa ◽

Middle Ear Cleft

AbstractA case is described of an extensive acquired cholesteatoma of the middle ear cleft which had invaded the middle cranial fossa and produced a mass effect on the temporal lobe. It had also extended into the labyrinth without causing elevation in the bone conduction threshold. Furthermore, even after total bony labyrinthectomy, there was very little elevation in these thresholds. The literature relating to hearing preservation after labyrinthectomy is reviewed.

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Clinical features and diagnosis

10.1093/med/9780199692736.003.0004 ◽

2012 ◽

Author(s):

Raymond W. Lam

Keyword(s):

Bipolar Disorder ◽

Major Depressive Disorder ◽

Differential Diagnosis ◽

Depressive Disorder ◽

Clinical Features ◽

Cognitive Symptoms ◽

Major Depressive ◽

Low Mood ◽

Different Types ◽

Variable Presentation

• Depression is associated with a number of physical, emotional, and cognitive symptoms.• Sub-typing of major depressive disorder has implications for treatment choice and selection.• The differential diagnosis of depression includes bereavement, bipolar disorder, and other medical or substance-induced conditions.Depression is associated with many different types of symptoms which can result to a variable presentation in any given person. The features of depression can be physical (sleep, energy, appetite, libido), emotional (low mood, anxiety, crying) or cognitive (guilt, pessimism, suicidal thoughts). ...

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