scholarly journals Percutaneous laser disc decompression in the treatment of detrusor-urethral dyssynergia in a female German Shepherd: a case report

2013 ◽  
Vol 58 (No. 6) ◽  
pp. 327-330
Author(s):  
S. Lew-Kojrys ◽  
Z. Adamiak ◽  
A. Pomianowski ◽  
W. Maksymowicz ◽  
M. Barczewska ◽  
...  
Keyword(s):  
Pharmacological Treatment ◽  
Adrenergic Receptor ◽  
Muscle Relaxants ◽  
Lumbosacral Spine ◽  
Test Results ◽  
German Shepherd ◽  
Alpha Adrenergic Receptor ◽  
Clinical Observations ◽  
Laser Disc ◽  
Voiding Difficulties

A 7-year-old female, German Shepherd with urinary and faecal voiding difficulties was admitted to the clinic. The patient was subjected to neurological, ultrasonographic and radiological examinations as well as blood and urine tests. Based on clinical observations and test results, the dog was diagnosed with detrusor-urethral dyssynergia. The prescribed pharmacological treatment consisted of alpha adrenergic receptor antagonists and skeletal muscle relaxants. The patient was catheterised daily, and Foley’s catheter was temporarily inserted. Pharmacological treatment was not effective, however, and the patient was subjected to an MRI examination of the lumbosacral spine which revealed L6–L7 dyscopathy. The dog was then subjected to percutaneous laser disc decompression. Pharmacological treatment was continued, and the catheter was left in place after surgery. Active urination was restored four days after surgery despite the presence of the catheter. The catheter was subsequently removed, and pharmacological treatment was gradually discontinued. The symptoms of dyssynergia subsided completely.  

scholarly journals Alpha-adrenergic receptor blockade and hyperaemic response in patients with intermediate coronary stenoses

2004 ◽  
Vol 25 (22) ◽  
pp. 2034-2039 ◽  
Author(s):  
E BARBATO ◽  
J BARTUNEK ◽  
W AARNOUDSE ◽  
M VANDERHEYDEN ◽  
F STAELENS ◽  
...  
Keyword(s):  
Adrenergic Receptor ◽  
Receptor Blockade ◽  
Alpha Adrenergic Receptor ◽  
Hyperaemic Response ◽  
Coronary Stenoses ◽  
Adrenergic Receptor Blockade

scholarly journals Platelet reactivity and its dependence on alpha-adrenergic receptor function in patients with ischaemic heart disease.

Heart ◽  
1983 ◽  
Vol 49 (1) ◽  
pp. 20-25 ◽  
Author(s):  
M Yokoyama ◽  
S Kawashima ◽  
S Sakamoto ◽  
H Akita ◽  
T Okada ◽  
...  
Keyword(s):  
Heart Disease ◽  
Ischaemic Heart Disease ◽  
Adrenergic Receptor ◽  
Platelet Reactivity ◽  
Receptor Function ◽  
Alpha Adrenergic Receptor

Muscarinic and alpha-adrenergic stimulation of Na and Ca uptake by dispersed lacrimal cells

1980 ◽  
Vol 239 (2) ◽  
pp. G99-G105 ◽  
Author(s):  
R. J. Parod ◽  
B. A. Leslie ◽  
J. W. Putney
Keyword(s):  
Lacrimal Gland ◽  
Adrenergic Receptor ◽  
Receptor Activation ◽  
Adrenergic Stimulation ◽  
Alpha Adrenergic Receptor ◽  
Ca Uptake ◽  
Isotope Technique ◽  
Ca Ions ◽  
Double Isotope

Rat lacrimal gland acinar cells were isolated and observed to be physiologically stable for several hours of incubation in vitro. With a double-isotope technique, it was found that carbachol and epinephrine stimulated the uptake of 22Na and 45Ca by lacrimal cells. These respnses were maximal at agonist concentrations of 10(-5) M and were blocked by atropine and phentolamine, respectively. It is concluded that muscarinic and alpha-adrenergic receptor activation increase the membrane permeability of the lacrimal gland acinar cell to Na and Ca, ions that may be important in the secretion of water by the lacrimal gland.

Dogfish pressor response to potassium blocked by magnesium and phentolamine

1982 ◽  
Vol 242 (3) ◽  
pp. R185-R188
Author(s):  
R. G. Carroll ◽  
D. F. Opdyke ◽  
N. E. Keller
Keyword(s):  
Adrenergic Receptor ◽  
Pressor Response ◽  
In Vitro Experiments ◽  
Spontaneous Release ◽  
Alpha Adrenergic Receptor ◽  
Receptor Sites ◽  
Catecholamine Levels ◽  
Chromaffin Tissue

In vivo infusion of MgCl2 blocks the dogfish pressor response to K+. This action of Mg2+ was contrasted to phentolamine in in vivo and in vitro experiments. Mg2+ blocks the spontaneous release of catecholamines from dogfish chromaffin tissue but does not alter the norepinephrine-induced contraction of the isolated dogfish artery. In vivo infusion of Mg2+ causes a significant decrease in resting catecholamine levels and diminishes the catecholamine release caused by K+ challenge. Both Mg2+ and phentolamine block the pressor action of K+, Mg2+ by preventing the K+-induced release of catecholamines and phentolamine by preventing the circulating catecholamines from interacting with alpha-adrenergic receptor sites.

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