scholarly journals Role of liquid-based cytology and cell block study of pleural fluid in the evaluation of cases of malignant Pleural effusion with special reference to immunohistochemistry

2021 ◽  
Vol 9 (3) ◽  
pp. 185-192
Author(s):  
Dr. Rama Saha ◽  
◽  
Dr. Samaresh Sardar ◽  
Dr. Smritiparna Das ◽  
◽  
...  
Keyword(s):  
Pleural Effusion ◽  
Malignant Pleural Effusion ◽  
Cell Block ◽  
Block Method ◽  
Cross Sectional ◽  
Male Predominance ◽  
Study Population ◽  
Liquid Based Cytology ◽  
Effusion Fluid

Introduction: Lung cancer is the most common primary tumor associated with malignant pleuraleffusion (MPE). In this study, we aim to use cell remnants for cell block preparation after performingliquid-based cytology (LBC) of effusion fluid. Immunohistochemistry was helpful to evaluate thosecases having diagnostic dilemmas in LBC and cell block. Method: It was a cross-sectional,prospective, single institution-based study, conducted in the department of Pathology incollaboration with the Department of Respiratory Medicine IPGMER & SSKM Hospital, from January2018 to June 2019 in the institution. Result: Most of the study population were in between the agegroup of 51 to 60 years with male predominance and with fever and cough being the predominantsymptoms. Liquid-based cytology was positive for malignancy in 58% of cases and suspicious ofmalignancy in 22% of cases of malignant pleural effusion and it had 95.35% sensitivity, 58.82%specificity in diagnosing malignant pleural effusion.LBC was done followed by cell block preparationsare studied further by Immunohistochemistry. Discussion: Morphological features were betteridentified by the cell block method when compared to LBC. Multiple sections can be obtained forspecial stain or IHC study which bridges the gap between cytology and histology.

scholarly journals Knowledge and awareness of precision medicine among dental students

2020 ◽  
Vol 11 (SPL4) ◽  
pp. 642-647
Author(s):  
Bipin M ◽  
Jeevitha M ◽  
Kavitha S
Keyword(s):  
Precision Medicine ◽  
Dental Students ◽  
Individual Variability ◽  
Medical Field ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Study Population

Precision medicine is an emerging approach for the treatment of diseases and prevention that takes into account individual variability in genes, environment and lifestyle of a person. Although the term precision medicine is relatively new, the concept has been a part of healthcare for many years. This study focuses especially to evaluate the knowledge on characteristics of precision medicine among dental students. The aim of this study is to analyse the knowledge and awareness of Precision medicine among dental students. A descriptive cross-sectional survey was conducted among dental students through a self-administrated questionnaire. The responses had been collected and statistically analysed. 61% of the study population were aware of Precision medicine and surprisingly, 82% of the respondents came across this term precision medicine. This study concludes that the dental students were aware of the term precision medicine, but they were not well aware of the role of precision medicine in the medical field.

scholarly journals Role of Liquid-based Cytology and Cell Block in the Diagnosis of Endometrial Lesions

2016 ◽  
Vol 129 (12) ◽  
pp. 1459-1463 ◽  
Author(s):  
Hui Zhang ◽  
Jia Wen ◽  
Pi-Li Xu ◽  
Rui Chen ◽  
Xi Yang ◽  
...  
Keyword(s):  
Cell Block ◽  
Liquid Based Cytology

scholarly journals The State of Cell Blocks and Ancillary Testing: Past, Present, and Future

2016 ◽  
Vol 140 (12) ◽  
pp. 1318-1322 ◽  
Author(s):  
Anjali Saqi
Keyword(s):  
Molecular Diagnostics ◽  
Significant Role ◽  
The State ◽  
Cell Block ◽  
Block Method ◽  
Alternative Techniques

Cell blocks are an integral part of cytology, but their utility is recognized probably more now than ever before, largely owing to the significant role they play in ancillary testing, particularly molecular diagnostics. Modifications to improve the cell block method initially introduced more than a century ago have been made over the years. Though their value is acknowledged and they are widely used across laboratories, cell block preparations are not standardized and results of ancillary testing performed on them are inconsistent. This article reviews the state of cell blocks—summarizes the more common, currently available and used methods and their corresponding advantages and shortcomings, outlines the role of alternative techniques (eg, smears), and proposes methods to optimize results.

scholarly journals Role of DR-70 immunoassay in suspected malignant pleural effusion

Lung India ◽  
2013 ◽  
Vol 30 (4) ◽  
pp. 321
Author(s):  
Amitabha Sengupta ◽  
Kaushik Saha ◽  
Debraj Jash ◽  
SourindraNath Banerjee ◽  
NirendraMohan Biswas ◽  
...  
Keyword(s):  
Pleural Effusion ◽  
Malignant Pleural Effusion

scholarly journals A Comparative Evaluation on the effect of Zinc-Probiotic combination versus Zinc alone therapy in children (3month-5year) with acute watery diarrhea attending the outpatient clinic of Sub-District hospital, Uttarakhand

2021 ◽  
Vol 9 (4) ◽  
pp. 263-268
Author(s):  
Dr. Mamta Nikhurpa ◽  
◽  
Dr. Renu Agnihotri ◽  
Keyword(s):  
Watery Diarrhea ◽  
Male Predominance ◽  
Watery Stool ◽  
Acute Watery Diarrhea ◽  
Group A ◽  
Study Population ◽  
The Mean ◽  
Group B ◽  
Time Required

Background: Diarrhea is the major cause of morbidity and mortality among children worldwide.Various studies were done on the role of zinc therapy and probiotic therapy in reducing the durationand severity of acute watery diarrhea. This study aimed to compare the effect of Zinc –probioticcombination versus Zinc only therapy in acute watery diarrhea in pediatric patients. Material andMethods: This was an open, randomized control trial in the pediatric outpatient department of Sub-District Female Hospital, Haldwani (Uttarakhand), from June 2020 till August 2020 for three months.Total 104 children aged six months to 5 years with acute diarrhea who met the inclusion criteriawere enrolled and divided into 52 patients each. 1stGroup A (n=52) received Zinc-Probioticscombination therapy, and 2ndGroup B (n=52) received Zinc only. Measurement of disease severitywas based on the frequency of diarrhea (times/day) and duration of diarrhea (hours) after initialdrug consumption. The resolution was assessed in mean remission time (time required to form solidstool from watery stool).Result: Among the study population in group A, 62% were male, 38%were female, and in group B, 65% were male & 35% were female. Male predominance was observedin both groups. The mean frequency of diarrhea before treatment in Group A was 7.46 ± 4.1times/day as compared to 6.69 ± 3.6 times/day in Group B. Mean duration of diarrhea in Group Awas 53.5 ± 30.5 hours as compared to 57.6 ± 34.3 hours in Group B. Conclusion: Combinationtherapy was more effective than Zinc only therapy in early remission and resolution of acute waterydiarrhea in children.

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