scholarly journals Correlation between type 2 diabetes mellitus and central corneal thickness: A cross-sectional study

2021 ◽  
Vol 6 (2) ◽  
pp. 35-38
Author(s):  
Dr. Jigish Desai ◽  

Background and Aim: Diabetes has emerged as an important global health concern because of itsvarious adverse effects on the ocular tissue. The present study was done to study the correlationbetween type 2 diabetes mellitus and central corneal thickness in patients coming to the tertiarycare institute of Gujarat, India. Material and Methods: The present study was conducted over 1year at the tertiary care institute of Gujarat, India.50 patients with type 2 diabetes mellituspreviously diagnosed by a physician on treatment and 50 age-matched controls who are non-diabetics on history and blood sugar levels were enrolled. The central corneal thickness wasmeasured using an ultrasound pachymeter using multiple reading single point modes by a singleperson. Results: The mean central corneal thickness in diabetics was 565 ± 21 micrometres and innon-diabetics was 517 ± 20 micrometres. The central corneal thickness was found to be higher inpatients with type 2 diabetes mellitus when compared to non-diabetics. Conclusion: Patients withtype 2 diabetes mellitus were found to have thicker corneas as compared to non-diabetics. Thisshould take into consideration while interpreting intraocular pressure and before any refractivesurgeries in diabetics.

2021 ◽  
Vol 7 (3) ◽  
pp. 554-561
Author(s):  
Chinnangolla Viveknandini Reddy ◽  
M H Reddy

To determine association between central corneal thickness and type 2 diabetes mellitus in patients attending outpatient department of Ophthalmology at a tertiary care centre in North Karnataka.This is a cross-sectional study conducted over a period of April 2018 – September 2020 on patients attending outpatient department of Ophthalmology at a tertiary care centre in North Karnataka. Study includes 168 subjects divided into 3 groups: 40 diabetics whose duration >10 years46 diabetics whose duration ≤10 yearsand 82 controls.Detailed ophthalmic examination was conducted in all patients and central corneal thickness was measured using ultrasound pachymetry. A statistically significant difference was found between mean central corneal thickness of diabetics (534.0581µ - right eye; 534.3605µ - left eye) and non-diabetics (525.8659µ - right eye; 525.8659µ - left eye); p value <0.05. Association between central corneal thickness and age, gender, laterality and duration of diabetes were not statistically significant. Patients with type 2 diabetes mellitus have thicker corneas as compared to non-diabetics. Henceforth, it is important to measure central corneal thickness in all diabetics, as it affects IOP measurement which is vital for early diagnosis and timely treatment of glaucoma.


2021 ◽  
Vol 69 (7) ◽  
pp. 1718
Author(s):  
Bithi Chowdhury ◽  
Sangeeta Bhadra ◽  
Pramod Mittal ◽  
Kishore Shyam

2021 ◽  
Vol 33 (1) ◽  
pp. 56
Author(s):  
Rajani Kadri ◽  
Namrata Sasalatti ◽  
Sudhir Hegde ◽  
AjayA Kudva ◽  
Devika Parameshwar ◽  
...  

2021 ◽  
pp. 1-11
Author(s):  
Baizid Khoorshid Riaz ◽  
Shahjada Selim ◽  
Megan Neo ◽  
Md Nazmul Karim ◽  
M. Mostafa Zaman

<b><i>Methodology:</i></b> Biochemically confirmed type 2 diabetes mellitus (T2DM) patients (<i>n</i> = 1,114) were recruited from the outpatient department of 2 tertiary care hospitals in Dhaka, Bangladesh. Face-to-face interview was conducted using a semi-structured questionnaire containing sociodemographic parameters and relevant information about depression and diabetes. Biochemical test results and treatment-related information were taken from patients’ records. The Hospital Anxiety and Depression Scale (HADS) was used to screen all patients for psychiatric manifestation. Those diagnosed by HADS were subsequently reassessed using structured clinical interview for DSM-5 Disorders – Clinician Version. T2DM diagnosed at age &#x3c;40 years were considered as early onset T2DM. Association between age of onset category and depression was assessed using multivariable mixed-effect logistic regression adjusting for random variation of the area of residence and plausible confounders. <b><i>Results:</i></b> Around a third of the participants (32.5%) were diagnosed with T2DM before the age of 40 years. Early onset T2DM patients were found to have 57% increase in the risk of developing depression (OR 1.57; 95% CI 1.13–2.28; <i>p</i> = 0.011) in comparison to those with usual onset T2DM (≥40 years). Among other factors a positive family history for diabetes (OR 1.33; 95% CI 1.03–1.78; <i>p</i> = 0.038), poor glycemic control (OR 1.31; 95% CI 1.03–1.68; <i>p</i> = 0.028), presence of 1, or more diabetic complications (OR 1.37; 95% CI 1.03–1.78; <i>p</i> = 0.011) also showed increased risk of depression. <b><i>Conclusion:</i></b> Early onset T2DM patients are at greater risk of developing depression. The finding is likely to help in setting preventive strategies aiming to reduce the presence of concomitant depression symptoms among diabetes.


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