scholarly journals Histopathological Study of Malignant Neoplasm of Breast of Different Age and Sex Groups In a Tertiary Care Hospital

2018 ◽  
Vol 5 (2) ◽  
pp. 42-44
Author(s):  
Nazmun Nahar ◽  
Mohammed Iqbal ◽  
Kazi Md Shahidur Rahman ◽  
Md Abdullah Yusuf ◽  
Shahed Iqbal ◽  
...  
Keyword(s):  
Invasive Ductal Carcinoma ◽  
Breast Neoplasm ◽  
Ductal Carcinoma ◽  
Tertiary Care ◽  
Malignant Neoplasm ◽  
Care Hospital ◽  
Age Group ◽  
Breast Lump ◽  
Malignant Breast ◽  
Age And Sex

Background: Various types of female breast cancer associated with rapidly increasing age incidence. Objective: The purpose of the present study was to find out the frequency of different types of malignant neoplasm of breast in different age and sex.Methodology: This cross-sectional study was carried out at the Department of Pathology, Chittagong Medical College, Chittagong, Bangladesh from May 2005 to June 2006. Patients presented with breast lump of different age and sex were subjected to this study. Details gross examination was done followed by H & E staining for histopathological study.Result: A total number of 48 samples were selected after fulfilling the inclusion and exclusion criteria. This present study conducted in 27 specimens out of 48 breast lump. Among these benign and malignant were 21 and 27, respectively. Majority of the malignancy found in age group 41-50 years. Histopathologically Invasive ductal carcinoma was common 81.5%.There was significant association between different age group and type of neoplasm. In relation to sex malignant breast neoplasm was more common in female.Conclusion: In conclusion invasive ductal carcinoma was the commonest lesion of breast. In relation to sex malignant breast neoplasm was more common in female.Journal of Current and Advance Medical Research 2018;5(2):42-44

scholarly journals The spectrum of palpable breast lesions- A cytopathological study of 1193 cases

2021 ◽  
Vol 7 (3) ◽  
pp. 144-149
Author(s):  
Manasa GC ◽  
◽  
Sneha SP ◽  
Adicherla Govardhan ◽  
◽  
...  
Keyword(s):  
Ductal Carcinoma ◽  
Tertiary Care ◽  
Needle Aspiration ◽  
Female Breast Cancer ◽  
Care Hospital ◽  
Age Group ◽  
Breast Lump ◽  
Palpable Breast ◽  
Needle Aspiration Cytology ◽  
Sensitivity Specificity

Introduction- The vast majority of the lesions that occur in the breast are benign. Much concern isgiven to malignant lesions of the breast because female breast cancer has now surpassed lungcancer as the leading cause of global cancer incidence in 2020. Fine needle aspiration cytology(FNAC) has good sensitivity, specificity and accuracy in the diagnosis of both neoplastic and non-neoplastic breast lump thereby assisting in early diagnosis and further management. The currentstudy was done to study the incidence and the different cytomorphological patterns of palpablebreast lumps by FNAC and consequently compare the results with studies in the literature.Materials and methods- This is a retrospective study conducted from January 2018 to December2020 in a tertiary care hospital. The three-year data is obtained from the records maintained in theFNA clinic. The patients were counselled before the procedure and informed consent was taken.Results- A total of 1193 breast lump cases were analysed in this 3-year study, there were 19 malepatients all of them presented with gynaecomastia and 1177 female patients. The patient’s agegroup ranged from 12 to 86 years. The commonest age group with the lesions 31-40 yearscomprising 326 cases (27.32%) followed 21-30 years age group in the second place with 307 cases(25.7%). Conclusion- In this study the most common benign neoplastic and malignant neoplasticbreast lumps are fibroadenoma and infiltrating ductal carcinoma respectively. Fibrocystic disease ofthe breast is the most common non-neoplastic breast lump.

scholarly journals Incidence and Patient Profile of Carcinoma Breast Patients Presenting in Surgical OPD in a Tertiary Care Hospital

2021 ◽  
Vol 15 (2) ◽  
pp. 65-68
Author(s):  
Sharmistha Roy ◽  
Mosammat Mira Pervin ◽  
Mohd Mejbahul Bahar ◽  
Samiron Kumar Mondal ◽  
Md Tariq Hasan
Keyword(s):  
Breast Cancer ◽  
Risk Factors ◽  
Cancer Biology ◽  
Tertiary Care ◽  
Locally Advanced ◽  
Metastatic Breast ◽  
Care Hospital ◽  
Age Group ◽  
Breast Lump ◽  
Patient Profile

Breast cancer is one of the common cancers in women that causes financial health burden and or death in Bangladesh. Economically we are slowly rising from low to middle income country, which is changing our women's lifestyle. Risk factors of breast cancer include lifestyle factors like- age at first childbirth, parity, using oral contraceptives, BMI; which are also changing in our women. This study will look at our current incidence and patient profile of breast cancer patient. This is a retrospective study done in BIRDEM General Hospital. One hundred patient presenting with breast lump during the period of September 2018 -May 2019 were selected by purposive sampling. In <30 years age group 2 (13.6%) patient had cancer, 41% at <40 years, 53% in 51-60 , 83% in 61-70 age group. Thirty four out of 100 breast lump patient were diagnosed with cancer. Eleven had early cancer, 20 had locally advanced cancer, 3 presented with metastasis. In our study risk factor assessment did not show significant increase risk of in patients who are having cancer compared to those having benign breast disease with similar risk factors. The big number of advance and metastatic breast cancers in our study indicates self-breast examination and breast cancer screening program is still inadequate. Further research is required to find out breast cancer biology and pathogenesis rather than blindly accusing urbanized life style. Faridpur Med. Coll. J. 2020;15(2): 65-68

scholarly journals Clinicopathological Variants of Breast Cancer in a Tertiary Care Hospital in Pakistan

2021 ◽  
Vol 15 (1) ◽  
pp. 28-31
Author(s):  
Raja Najam ul Haq ◽  
Keyword(s):  
Breast Cancer ◽  
Invasive Ductal Carcinoma ◽  
Ductal Carcinoma ◽  
Lobular Carcinoma ◽  
Tertiary Care ◽  
Age Groups ◽  
Subsequent Treatment ◽  
Cancer Type ◽  
Care Hospital ◽  
Elderly Age

Background: Breast cancer is a growing phenomenon among females which has ever-lasting ramifications on the patient as well as the family. The only way of subjugating breast cancer is through an efficient and effective screening and subsequent treatment process. Objective: This study aimed at identifying the different clinicopathological patterns of breast cancer and the age group most frequently targeted by CA breast. Study Design: A prospective study. Settings: Fauji Foundation Hospital (FFH), Rawalpindi and Foundation University Medical College (FUMC) Pakistan. Duration: Six months from January 2018 to June 2018. Methodology: This study included 224 female patients, irrespective of their nationality by convenience sampling, who underwent any kind of breast surgery. The patients were evaluated according to their age, side of breast involved, site of lump in the breast, histopathology report and type of lesion (inflammatory, benign or malignant). The data was entered and analyzed using IBM SPSS version 25. Results: Our study sample of 224 individuals was found to have about 23 different histopathological variants of breast cancer. Invasive ductal carcinoma was found in almost all age groups and it was also the most common variant (80.8%), followed by invasive lobular carcinoma (4%). Majority of the cases were recorded in the elderly age bracket from 55 to 65 years. Right breast was found to be involved in 53.6% of the cases whereas left breast involvement was at 44.2%. 5 patients had lesions in both of their breasts. Upper outer quadrant was affected in 88% females followed by upper inner quadrant (6.7%). All four quadrants were involved in only 3 patients. Conclusion: This study concluded that invasive ductal carcinoma is the commonest clinical as well as pathological type of CA breast. 181 females out of a total of 224 had invasive ductal carcinoma. Therefore, this particular breast cancer type merits our special attention. Our study further concluded that most of the breast pathologies were found in elderly females aged between 55 and 65 years.

scholarly journals Role of Triple Assessment of Breast Lump in Premenopausal and Postmenopausal Women -A Comparative and Descriptive Study

2020 ◽  
Vol 11 (SPL4) ◽  
pp. 1390-1397
Author(s):  
Devi Priya S ◽  
Lakshmana R ◽  
Abhilash M ◽  
Sujeeth A ◽  
Govinda Raju C
Keyword(s):  
Postmenopausal Women ◽  
Invasive Ductal Carcinoma ◽  
Ductal Carcinoma ◽  
Premenopausal Women ◽  
Breast Disease ◽  
Breast Lump ◽  
Triple Assessment ◽  
Menopausal Women ◽  
Malignant Breast ◽  
Post Menopausal

Triple assessment of breast is based on clinical examination, histological and radiological study where in our study, the pattern of breast swelling in a premenopausal and postmenopausal woman was compared. A total of 150 female patients with palpable breast lump went through clinical examination, FNAC, USG breast while mammogram & core needle biopsy was done in selected patients. Histopathological examination of the specimen was done for all post-operative patients. Benign & malignant breast lesion accounted for 82(54.6%) & 68(45.3%) respectively. Based on the incidence of benign breast lump & malignant breast lump among pre menopausal women, it was 79% & 21% respectively while in post menopausal women it was  21.9% & 78.1%. The most common type of breast lump among the pre and post menopausal women was fibroadenoma 56.9% & Invasive ductal carcinoma 59.3% respectively. The most common benign breast lump & malignant breast lesion based on the histological pattern among the premenopausal women was fibroadenoma 72% & Invasive ductal carcinoma 50% while in postmenopausal women it was fibroadenosis 71.4% & Invasive Ductal Carcinoma 76%. Based on the hormonal status(ER/PR) of pre and postmenopausal women positivity was seen majorly in post menopausal women 82.3% compared to premenopausal women 17.7%. In our study, the malignant breast disease was more common in post menopausal, while benign breast disease was common in pre menopausal women.  Triple assessment in evaluating a breast lump is per se a reliable & valid tool in the armamentarium of treating clinician with very high diagnostic accuracy.

Prescribing trends of antidiabetic drugs in diabetic and hypertensive diabetic patients in an urban tertiary care hospital of Bangladesh

2017 ◽  
Vol 3 (3) ◽  
pp. 338-343
Author(s):  
Mohammad Didar Khan ◽  
Md. Ibrahim ◽  
Md. Mizanur Rahman Moghal ◽  
Dipti debnath ◽  
Asma Kabir ◽  
...  
Keyword(s):  
Urban Areas ◽  
Tertiary Care ◽  
Diabetic Patients ◽  
Care Hospital ◽  
Age Group ◽  
Microsoft Excel ◽  
Patient Profile ◽  
Prescribing Trends ◽  
Medical University ◽  
Insight Into

Objective: The present epidemiological study was conducted with the objectives of providing an insight into the current use of antidiabetic medications to diabetics and hypertensive diabetics in urban areas and determining how the patient factors influence the prescribing of antidiabetic medications. Methodology: Data of patients of past two years were collected from Bangabandhu Sheikh Mujib Medical University (BSMMU) Hospital, Dhaka, Bangladesh. The details were entered in the structured patient profile form. Data were statistically analyzed using the Microsoft Excel 2007 software. Result: A total of 958 patient’s data were collected and analyzed of which 632 (65.97 %) were males and 326 (34.03 %) were females. These patients were further categorized based on their age. 330 patients (34.45 %) belonged to the age group 20 – 44 years, 504 (52.61 %) to the age group 45 – 65 years and 124 (12.94 %) to the age group 65 – 80 years. 684 (71.4%) patients out of the 958 patients studied were suffering from coexisting hypertension. Co-existing hypertension was found to be more prevalent in the age group 45 – 65 years (67.69%) and was found more in females (84.04%). Conclusion: Metformin was the oral hypoglycemic which was the highest prescribed. In hypertensive diabetics Metformin and Pioglitazone were most frequently prescribed drugs. Biguanides and Insulin were the most commonly prescribed antidiabetics. A combination of two or more drugs of different classes was prescribed to hypertensive diabetics. It is necessary to have an improved understanding of the etiology and pathophysiology of diabetes to focus on research efforts appropriately.

A Study on prescribing pattern of drugs in orthopaedic in-patient department at a tertiary care hospital in Guntur region

2020 ◽  
Vol 8 (2) ◽  
pp. 60-70
Author(s):  
Anjani Teja Ch ◽  
Ramesh babu K ◽  
Leela subramanyam S ◽  
Janani Y ◽  
Eswar Sai Kiran K ◽  
...  
Keyword(s):  
Tertiary Care Hospital ◽  
Care Delivery ◽  
Tertiary Care ◽  
Essential Medicine ◽  
Care Hospital ◽  
Age Group ◽  
Common Condition ◽  
Prescribing Pattern ◽  
Prescribing Indicators ◽  
Bed Days

The descriptive observational study was conducted over six months among inpatients of the orthopaedics department. The aim is to observe the prescribing pattern of drugs, to find out the percentage of analgesics given and most commonly prescribed analgesic, to compare the prescribed drugs whether they are in NLEM, WHO list and calculate DDD/100 Bed-days and to analyze the drugs for WHO prescribing drugs. A total of 250 patients were included in the study. Out of this, 168 were male, and 82 were female. Most of the patients were in the age group of 31-40[45 in number with 18%]. The most common condition was found to fracture [113 in number with 95.2%]. Commonly prescribed drugs were analgesics 447 with 26.76%. Among all the NSAID's, PCM was most commonly prescribed analgesic with 34.4%. The highest no, of drugs was found to be 4drugs/prescription with 24%. Monthly one analgesic was prescribed per prescription with 38.8%. Utilization of analgesics in term of DDD/100 Bed-days was 55.26; Drugs will be evaluated per prescription as per prescribing indicators of WHO was done, the average no. of drugs per prescription was found to be 0.45, percentage of drugs prescribed by generic name was found to be 13.3%, percentage of encounters with antibiotics prescribed were found to be 94.4%, In ratio percentage of drugs prescribed from the national list of essential medicine was found to be 92.6%. This study would help to facilitate better health care delivery.

First and second wave of COVID-19: A comparative study of tertiary care hospitalized patients in Jalgaon, Maharashtra

2021 ◽  
Vol 19 (3) ◽  
pp. 23-29
Author(s):  
Yogita G Bavaskar ◽  
Keyword(s):  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Clinical History ◽  
Care Hospital ◽  
Age Group ◽  
Number Of Patients ◽  
The Mean ◽  
Collection Form ◽  
Time Of Admission ◽  
Second Wave

Background: Most of the countries including India have witnessed two or more waves of Covid 19 pandemic. The present study was conducted to compare the differences in clinico-demographic characteristics and outcomes of Covid 19 patients admitted in first and second wave of Covid 19 pandemic in a tertiary care hospital at Jalgaon, Maharashtra. Methods: A retrospective observational study was conducted at a tertiary care Dedicated Covid hospital for Covid 19 at Jalgaon, Maharashtra. All microbiologically proven corona positive patients were included in the study. The demographic records and clinical history was extracted from the case history sheets of the patients from first as well as second wave using standardized data collection form. Clinical outcome of the patients, i.e., development of complications, death or discharge was also recorded for each enrolled subject. Results: 3845 patients of Covid-19 admitted in the hospital during the first wave of epidemic and 2956 patients during second wave of the epidemic were included in the study. The mean age of patients admitted in the second wave was significantly lower as compared to first [48.77(15.31) years vs 50.23 (14.33) years, P<0.005]. There is increase in proportion of patients in the age group of < 15 years in second wave as compared to first wave (74/2956, 2.5% vs 52/3845, 1.3%). The number of patients requiring admission in ICU at the time of admission increased by 13% in second wave as compared to first wave. [827/2956 (28%) vs 577/3845(15%), P<0.0001]. More than half of the patients who got admitted for Covid 19 in first as well as second wave were having one or more comorbidities.But the proportion of the patients with previous co-morbities was significantly higher in second wave (1684/2956, 57% vs 1960/ 3845, 51%, P= 0.0004). The mortality was also higher in second wave (533/2956, 18.03% vs 541/3845, 14%, P=0.0004). Conclusions: The demographic, clinical characteristics and outcome of Covid 19 patients was different in first and second wave of pandemic with involvement of younger patients, increased rates of admission to ICU and more mortality in the second wave as compared to first wave of the pandemic.

A CLINICOEPIDEMIOLOGICAL STUDY ON PAEDERUS DERMATITIS IN A TERTIARY CARE CENTRE, CHENNAI

2021 ◽  
pp. 25-27
Author(s):  
P. Mohan ◽  
P. Revathi Guru ◽  
V. Sudha ◽  
L. Balamurugan ◽  
Pavithra Gunasekaran ◽  
...  
Keyword(s):  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Sudden Onset ◽  
The Body ◽  
Care Hospital ◽  
Age Group ◽  
Common Condition ◽  
Tertiary Care Centre ◽  
Linear Lesions ◽  
Paederus Dermatitis

Paederus dermatitis is a form of irritant contact dermatitis due to contact with certain insects of the genus Paederus presenting with mostly erythematous linear lesions of sudden onset on exposed parts of the body. To study the clinico epi Aim: demiological features in patients with Paederus dermatitis. A retrospective analysis of clinicoepidemiological Materials & Methods: features of patients affected with Paederus dermatitis who had attended the Dermatology OPD, in a tertiary care hospital between January 2018 to December 2019 was done. All the required data had been collected from the OPD records and details were tabulated and analysed. A total of 56 patients had been affected with Result: Paederus dermatitis during the study period, of which 32 were males and 24 were females. 41out of 56 (73.21%) of patients presented between the months of August and December. Most common age group affected were between 11 to 30 yrs, with front and back of neck being the most common affected sites. In 42 out of the 56 patients the lesions resolved with post inammatory hyperpigmentation. Conclusion: Paederus dermatitis is a common condition that is often misdiagnosed and hence awareness is required for the clinicians and the general public to prevent it.

Aetiological Outcome of Mesenteric Lymphadenopathy and Pain Abdomen in Paediatric Population at a Tertiary Care Hospital (MRIMSHyderabad) - A Hospital Based Prospective Observational Study

2021 ◽  
Vol 8 (29) ◽  
pp. 2601-2608
Author(s):  
Dileep Kumar Allagadda ◽  
Harikrishna Appana ◽  
Ramu Pedada ◽  
Deepika Gurram ◽  
Ditin Joseph
Keyword(s):  
Abdominal Pain ◽  
Observational Study ◽  
Prospective Observational Study ◽  
Tertiary Care ◽  
Paediatric Population ◽  
Etiological Agent ◽  
Parasitic Infections ◽  
Care Hospital ◽  
Age Group ◽  
Mesenteric Lymphadenitis

BACKGROUND Abdominal pain is a common disorder in children and adolescents worldwide with prevalence rate ranging from 20 - 25 % in school-going children in India. It is a frustrating concern to the child, parents and the physician. Even though abdominal pain is one of the most common complaints in children, it poses a diagnostic challenge owing to the variety of underlying causes. The purpose of this study was to evaluate the aetiology of abdominal pain associated with significant mesenteric lymphadenopathy in a paediatric population. METHODS This is a hospital based prospective, observational study done in Department of Paediatrics, Malla Reddy Institute of Medical Sciences (MRIMS), Hyderabad. RESULTS Out of the 65 children studied, 30.8 % were of 5 - 8 years age group, 36.9 % were 9 - 12 years age group and 32.3 % were 13 - 15 years age group. In our study, we found 50.8 % were boys and 49.2 % were girls. 20 % of them were having fever, 16.9 % were having cough, 16.9 % were having diarrhoea, 13.8 % were having sore throat, 16.9 % dysuria, and 15.4 % were having constipation. All patients in our study group underwent ultrasound of abdomen. All cases were having significant mesenteric lymphadenopathy (more than 5 mm in short axis with three or more number of lymph nodes). In 53.8 % cases, etiological agent for the mesenteric lymphadenopathy was not proved with our investigations. In the remaining 46.2 % of children, cause of mesenteric lymphadenopathy was proved and 38.5 % were bacterial infections, 6.2 % were viral infections and 1.5 % were parasitic infections. CONCLUSIONS It is important to recognise mesenteric lymphadenitis as a clinical entity in paediatric cases presenting with abdominal pain. They should be evaluated for an etiological agent and if no proven source of infection and etiological agent is found, it can be considered as functional abdominal pain. If we are able to get a proper etiological diagnosis in these cases, we could treat them and we could make huge difference in terms of quality of life. KEYWORDS Abdominal Pain, Mesenteric Lymphadenitis, Ultrasound, Significant Mesenteric Lymphadenopathy

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