scholarly journals Cytological Study of Palpable Breast Lump Presenting in Eastern Nepal

2017 ◽  
Vol 1 (1) ◽  
pp. 27-32
Author(s):  
M. Singh ◽  
S.U. Kafle ◽  
K.K. Jha
Keyword(s):  
Benign Lesion ◽  
Significant Proportion ◽  
Needle Aspiration ◽  
Age Group ◽  
Breast Lump ◽  
Pathologic Assessment ◽  
Malignant Lesions ◽  
The Common ◽  
Palpable Breast ◽  
Needle Aspiration Cytology

Introduction Breast lump constitute significant proportion of surgical cases. It is necessary to distinguish between benign and malignant lesions for definite treatment. Fine needle aspiration cytology (FNAC) is widely adopted for the pathologic assessment because of its accuracy and ease of use.Objective The present study was done to find out the frequency of various patterns of breast lesion on FNAC and the common age - group in which the lesions occurs.Methodology This is a four years retrospective study carried out from December 2011 to January 2016. The 553 patients who presented with palpable breast lump, and have underwent FNAC irrespective of age and sex were included in the study. All the datas were collected from the patients record form. FNAC findings were correlated with the data from histopathology records to determine the sensitivity and specificity of FNAC.Results The majority of the patients were female and majority of lump was benign. Fibroadenoma was the most common lesion accounting for 32.18 % of all lesions and most commonly occurring in age group between 21 -30 years. Fibrocystic disease was second common benign lesion accounting for 30.56 also commonly accounting in the age group 21- 30 years. Carcinoma breast was seen in 5.42 % of cases (30/553) occurring most commonly in the female patients above 30 years of age. Most common age group for gynaecomastia in male breast was 11 – 20 years.Conclusion FNAC is a rapid and safe method for diagnosing palpable breast lump into benign and malignant categorizes and thus avoiding unnecessary surgery.Birat Journal of Health Sciences 2016 1(1): 27-32

scholarly journals Study of clinical, imaging and pathological assessment of breast lumps: an observational study

2020 ◽  
Vol 7 (5) ◽  
pp. 1452
Author(s):  
Sumedha Laul ◽  
Divish Saxena ◽  
Nitin Wasnik
Keyword(s):  
Final Diagnosis ◽  
Needle Aspiration ◽  
Age Group ◽  
Breast Lump ◽  
Aspiration Cytology ◽  
Malignant Breast ◽  
Palpable Breast ◽  
Needle Aspiration Cytology ◽  
Breast Lumps

Background: A palpable lump in a woman’s breast could be benign or malignant and it requires prompt evaluation to confirm or exclude cancer. This study aims to establish the correlation between clinical and radiological parameters for provisional diagnosis of breast lumps and the role of histopathology for final diagnosis of these breast lumps.Methods: Total 275 female patients with palpable breast lumps were included in the study, where a detailed history was recorded and clinical examination was done. All patients underwent ultrasonography of the breast along with fine needle aspiration cytology or histopathology, wherever indicated.Results: Benign breast lumps were found more commonly in 18-30 years of age group whereas malignant breast lumps were seen more commonly in the 41-60 years age group and the incidence increased with age. Fixity to skin was present in 5.1% and fixity to chest wall was present in 5.8% respectively, and all of these cases turned out to be malignant.Conclusions: Attributing factors for suspicion of malignant lumps are advanced age, fixity to surrounding structures, presence of ulceration and peau’d orange breast skin appearance. Although for confirmation of malignancy from a suspected breast lump requires either cytology or histopathology of the excised specimen.

scholarly journals The spectrum of palpable breast lesions- A cytopathological study of 1193 cases

2021 ◽  
Vol 7 (3) ◽  
pp. 144-149
Author(s):  
Manasa GC ◽  
◽  
Sneha SP ◽  
Adicherla Govardhan ◽  
◽  
...  
Keyword(s):  
Ductal Carcinoma ◽  
Tertiary Care ◽  
Needle Aspiration ◽  
Female Breast Cancer ◽  
Care Hospital ◽  
Age Group ◽  
Breast Lump ◽  
Palpable Breast ◽  
Needle Aspiration Cytology ◽  
Sensitivity Specificity

Introduction- The vast majority of the lesions that occur in the breast are benign. Much concern isgiven to malignant lesions of the breast because female breast cancer has now surpassed lungcancer as the leading cause of global cancer incidence in 2020. Fine needle aspiration cytology(FNAC) has good sensitivity, specificity and accuracy in the diagnosis of both neoplastic and non-neoplastic breast lump thereby assisting in early diagnosis and further management. The currentstudy was done to study the incidence and the different cytomorphological patterns of palpablebreast lumps by FNAC and consequently compare the results with studies in the literature.Materials and methods- This is a retrospective study conducted from January 2018 to December2020 in a tertiary care hospital. The three-year data is obtained from the records maintained in theFNA clinic. The patients were counselled before the procedure and informed consent was taken.Results- A total of 1193 breast lump cases were analysed in this 3-year study, there were 19 malepatients all of them presented with gynaecomastia and 1177 female patients. The patient’s agegroup ranged from 12 to 86 years. The commonest age group with the lesions 31-40 yearscomprising 326 cases (27.32%) followed 21-30 years age group in the second place with 307 cases(25.7%). Conclusion- In this study the most common benign neoplastic and malignant neoplasticbreast lumps are fibroadenoma and infiltrating ductal carcinoma respectively. Fibrocystic disease ofthe breast is the most common non-neoplastic breast lump.

scholarly journals Fine Needle Aspiration Cytology of Palpable Breast Lumps - Their Cytological Spectrum and Histopathological Correlation

KYAMC Journal ◽  
2017 ◽  
Vol 7 (2) ◽  
pp. 780-786
Author(s):  
Shaheen Akter ◽  
Md Jahidul Islam ◽  
Md Shariful Haque
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Breast Lump ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Histopathological Correlation ◽  
Palpable Breast ◽  
Needle Aspiration Cytology ◽  
Breast Lumps

Background: With the advent of fine needle aspiration cytology (FNAC), the approach to diagnosis and management of breast lumps has been revolutionized and it has high sensitivity and specificity.Aim: In this study we analyze the spectrum of FNAC diagnoses in breast lumps and compare the diagnostic accuracy of fine FNAC in differentiating the benign and malignant lesions of breast lumps with histopathological correlation.Materials & Methods: Two years prospective study was conducted in our institution and in that 490 aspirations, including 6 bilateral were performed. Suppurative and inflammatory lesions were excluded from the total aspirates. The cytological diagnosis was classified into 3 groups benign, suspicious and malignant. After this reporting all the available 94 cases were later subjected to mastectomy or open/excision biopsy and followed-up by histopathological confirmation. Later diagnostic accuracy of cytology reporting was compared with that of histopathology.Results: A total of 490 FNAC cases were reported including 373 as benign, 4 as suspicious for carcinoma and 113 as carcinoma. Majorities were premenopausal females and commonest age group was 31-40 years. Among them only 94 cases were followed-up by histopathologic confirmation. In histopathological correlation study, we had accuracy rate of 100% for benign lesion and 92.10% for malignant lesion with false negative rate of 7.90% and false positive rate of zero with fine needle aspiration cytology in the diagnosis of palpable breast lump. The overall sensitivity of fine needle aspiration in diagnosing the palpable breast lump is 92.10%, specificity is 100%, positive predictive value is 100% and negative predictive value is 94.91%.Conclusion: FNAC in experienced hands is a very useful tool with very high specificity and rare false positive result. Sensitivity can be further improved with clinical and imaging correlation.KYAMC Journal Vol. 7, No.-2, Jan 2017, Page 780-786

scholarly journals FNAC and histopathological correlation of salivary gland lesions: an observational study

2017 ◽  
Vol 4 (7) ◽  
pp. 2148 ◽  
Author(s):  
Sneha Kakoty ◽  
Tridip Dutta Baruah ◽  
C. P. Ganesh Babu
Keyword(s):  
Salivary Gland ◽  
Observational Study ◽  
Needle Aspiration ◽  
Age Group ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Histopathological Correlation ◽  
Neoplastic Lesions ◽  
Malignant Lesions ◽  
Needle Aspiration Cytology

Background: Fine needle aspiration cytology (FNAC) is a sensitive and specific and yet an economically effective technique for diagnosis of salivary gland lesions. FNAC of salivary glands has achieved a pivotal role in the diagnosis and management of salivary gland lesions since its induction by Stewart et al in 1933. However, it has always been under scrutiny when compared to histopathology. Histopathology of salivary gland lesions is still the final method to establish diagnosis and predicting prognosis in these lesions.1Methods: A prospective observational study of 50 patients with salivary gland lesions was done at Gauhati Medical College and hospital from June 2011 to May 2012. 39 patients underwent histopathological confirmation. Cases with histopathological correlation were included in calculating diagnostic accuracy. The cytological findings were correlated with that of the histopathological diagnosis to obtain the accuracy of the cytological diagnosis. The parameters of diagnostic validity of the cytological technique in terms of sensitivity, specificity and predictive value were evaluated.Results: Study population included patients of age group ranging from 13-70 years with median age group being 31-40 years (30%). 54% of the affected patients were male with the parotid being the most commonly involved gland (62%). Neoplastic lesions constituted the major bulk of the lesions (39 cases, 78%) with benign tumours constituting 54%. The most commonly involved benign neoplastic lesion was pleomorphic adenoma (22cases, 44%). Among the non-neoplastic lesions (22%), the acute sialadenitis was frequently noted. Histopathological correlations were available in 39 cases with 11 cases being the malignant lesions. The acute sialadenitis lesions did not undergo histological examination. 28 cases of non-malignant lesions underwent the histological confirmation. In the present study, the specificity and the sensitivity were found to be 96.42% and 90.91% respectively. The predictive value of salivary gland cytology was 90.91% and diagnostic accuracy was 94.87%.Conclusions: Fine Needle Aspiration Cytology is thus a safe, reliable, quick, convenient and accurate method of diagnosis and should be considered as one of the first line of investigations in the evaluation of salivary gland lesions.

scholarly journals Different Types of Breast Lump in Relation to Different Age Groups

2014 ◽  
Vol 8 (2) ◽  
pp. 56-58
Author(s):  
ABM Zafar Sadik ◽  
Md Mahmudul Hasan ◽  
Nur-E-Zannat Afroza Haque ◽  
Farid Uddin Ahmed ◽  
Md Zahidul Kabir
Keyword(s):  
Breast Carcinoma ◽  
Age Groups ◽  
Breast Disease ◽  
Needle Aspiration ◽  
Breast Lump ◽  
College Hospital ◽  
Medical College ◽  
Group A ◽  
Palpable Breast ◽  
Needle Aspiration Cytology

This prospective observational study was carried out in the inpatient and outpatient department of surgery at Shaheed Ziaur Rahman Medical College Hospital, Bogra, during the period of 01.07.2008 to 31.12.2008 with a view to find out the incidence of breast carcinoma, fibroadenoma or other pathology in different age group. A total 130 patients with palpable breast lump were included in the study. Age of the patients was between 11 to 70 years. In most of the patients with breast lump Fine Needle Aspiration Cytology and biopsy were done. Sometimes ultrasonography, mammography and other routine investigations were also done. Among the study population 53.85% had benign lesions, Breast carcinoma accounted for 46.15% cases, fibroadenoma for 40.76% and fibroadenosis were in 10% cases. Fibroadenoma was common in second and third decade, while carcinoma of breast was common in third and fourth decade in this study. Here we attempted to find out the age incidence of breast lump and its correlation with clinical features, FNAC findings and histopathological report to improve the accuracy of diagnosis and management of breast disease. DOI: http://dx.doi.org/10.3329/fmcj.v8i2.20369 Faridpur Med. Coll. J. 2013;8(2): 56-58

scholarly journals Mammographic evaluation of palpable breast masses with pathological correlation: a tertiary care centre study in Nepal

1970 ◽  
Vol 32 (2) ◽  
pp. 21-25 ◽  
Author(s):  
G Gurung ◽  
RK Ghimire ◽  
B Lohani
Keyword(s):  
Breast Cancer ◽  
Benign Lesion ◽  
Tertiary Care ◽  
False Negative ◽  
Malignant Lesion ◽  
Institute Of Medicine ◽  
Breast Lump ◽  
Major Health Problem ◽  
Malignant Lesions ◽  
Palpable Breast

Introduction: Breast cancer is one of the major health problem for all countries. . In Nepal , breast cancer is the second most common cancer in female. Early detecting tools like mammography can able to detect location , size, morphology, and nature of breast lesions that can help to reduced mortality and morbidity from breast cancer significantly. Methods: This prospective study was carried out at the department of Radiology, Surgery and Pathology for a period of one year. A total of 100 patients with clinically palpable breast lump were subjected to mammography and subsequently to FNA or biopsy. The mammograms were reviewed by two senior consultant radiologists and pathology by a senior pathologist. Results: Out of 100 patients, 65% had mammographic features of benign lesion and 35% had features of malignancy. Pathology revealed 64% of lesion to be benign and 36% of lesion to be malignant. There were four false negative (6.2%) and three false positive (8.6%) cases. The sensitivity and specificity of mammography were 88.9% and 95.53% respectively. The mean age of patient with malignant lesion was 46.3 years (SD=11.5) and 34.7 years (SD=10.6) for benign lesions. Among malignant lesion 37.1% had lobulated, 14.3% had oval, 31.4% round and 17.1% had irregular shape with spiculated margin in 60% and indistinct margins in 34.3%. Among benign 7.7% showed lobulated shape, 41.5% oval and 50.8% round shape. Circumscribed margin was found in 93.9% of benign and 5.7% of malignant lesions. Punctuate and polymorphic calcification was found in malignant lesions (25.7% and 5.7%). Secondary changes were found in only in the malignant cases. Halo sign was found only in benign cases and most common in fibroadenoma (38.4%). Conclusions: Mammography is an effective diagnostic tool for benign and malignant characteristic of palpable breast mass. Keywords: Breast lump; mammography; micro calcification DOI: http://dx.doi.org/10.3126/joim.v32i2.4940 Journal of Institute of Medicine, August, 2010; 32: 21-25

scholarly journals Fine needle aspiration cytology (FNAC) in pre-operative diagnosis of breast lesions in Kadapa region of Andhra Pradesh, India

2017 ◽  
Vol 4 (12) ◽  
pp. 4062
Author(s):  
Chakarala Obula Reddy ◽  
Garisa Chandra Mohana Reddy
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Breast Lesions ◽  
Breast Lump ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Palpable Breast ◽  
Needle Aspiration Cytology

Background: Various diagnostic methods have been developed to evaluate the palpable and non-palpable breast lesions, but Fine needle aspiration cytology of the palpable breast masses have become increasingly popular as a diagnostic technique to assess the breast lesions. To study the role of FNAC in diagnosis of breast lumps.Methods: 60 female patients (11-74 years age group) with palpable breast lump were utilized to study the role of Fine needle aspiration cytology for clinically palpable breast lump was carried out in Fathima Institute of Medical Sciences, Kadapa, Andhra Pradesh.Results: Fine needle aspiration cytology revealed benign in 22 patients, suspicious in 3 and 35 malignant lesions were 93.10% with false negative rate of 6.9% and false positive rate of 0%. The overall sensitivity of fine needle aspiration cytology in diagnosing the palpable breast lump in our study was 93.10%, specificity was 100%, positive predictive of 100% and negative predictive value of 90.47%.Conclusions: FNAC is easy to perform and painless procedure and standard tool for diagnosis of breast lumps with high percentage of true positives without virtual complications.

scholarly journals Frequency of Fine Needle Aspiration Cytological Category C5 in Breast Lesions among Females of Various Age Groups

2021 ◽  
Vol 15 (6) ◽  
pp. 1481-1483
Author(s):  
S. Yaseen ◽  
M. Ali ◽  
F. Mahmood ◽  
S. Mudassar ◽  
U. Nisar
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Age Groups ◽  
Needle Aspiration ◽  
Breast Lesions ◽  
Age Group ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Palpable Breast ◽  
Needle Aspiration Cytology

Background: Benign as well as malignant neoplasm of breast still appears to be the prime tumour among females and the prevalence of the disease is increasing all over the countries. The likelihood of emergence of breast neoplasm is linked to a number of factors i.e. reproductive life events and the factor of lifestyle that modify levels of endogenous sex hormones. One of most important risk factors is growing old age. Fine needle aspiration cytology (FNAC) is a least traumatic, reliable simple, complication free technique and economical for the diagnosis of mass lesions. It can be easily repeated if an adequate aspirate is not obtained. Aim: To determine the frequency of cytological category of FNAC C5 of breast lesion among different age groups. Study Design: Cross sectional comparative research study Place and Duration of Study: Department of Histopathology, Shaikh Zayed Hospital, Lahore from 21st January 2016 to 22nd September 2016. Methodology: One hundred and twenty female patients selected who presented with complain of palpable lesion in breast and was correlated with physical examination recording the size and consistency of mass. The procedure was performed on patients with complete clinical and radiological work up. After preparation of direct smear, slides were processed according to routine processing and then stained with H&E and Giemsa. Results: Thirty (25.80%) were between 18-30 age group while 42(35.00%), 47(39.20%) were between 31-45 and 46-60 age groups respectively. Though majority of FNAC cases were found in age group 31–45 but there was no significant difference among three groups by age. Conclusion: Malignancy in palpable breast masses can surely be diagnosed by a combination of clinical examination of breast and FNAC which when performed by a dedicated cytopathologist should be an integral part of a breast screening service. Middle age group had highest frequency but difference was insignificant. Keywords: Fine needle aspiration cytology, Palpable breast lesions, Age groups

scholarly journals Correlation between Robinson’s cytological grading with Modiied Bloom-Richardson histopathological grading for breast carcinoma

2015 ◽  
Vol 5 (10) ◽  
pp. 791-797
Author(s):  
S Chalise ◽  
A Jha ◽  
PR Neupane ◽  
SB Pradhan ◽  
R Pathak
Keyword(s):  
Breast Carcinoma ◽  
Relevant Information ◽  
Needle Aspiration ◽  
Breast Lump ◽  
Fine Needle ◽  
Triple Assessment ◽  
Grade Ii ◽  
Palpable Breast ◽  
Needle Aspiration Cytology ◽  
Grade Iii

Background: Invasive breast carcinoma is the most common carcinoma in women. Fine needle aspiration cytology is the important part of triple assessment of the palpable breast lump. Robinson’s cytological grading can be done in fine needle cytology smears of breast lump. The aim of this study is to grade breast tumor on cytology according to Robinson cytological grading and to correlate with histopathological grading.Materials and methods: This prospective study was done in Department of pathology, Bhaktapur Cancer Hospital from 1st April 2014 to 30thjuly 2015. A total of 58 cases of cytologically confirmed breast carcinoma were included in this study and correlated with histopathological findings. Robinson’s cytological grading was done on cytology smears and modified Bloom-Richardson grading was done on histological sections. Correlation between these two grading was done by using spearman’s correlation coefficient.Results: Cytologically, most common tumor was grade II (62.1%) followed by grade I (19%) and grade III (19%). Histologically, most common tumor was grade II (63.8%) followed by grade III (22.4%) and grade I (13.8%). High concordance rate was found in grade II tumor (80%) with absolute concordance being 65.9%. On cytology, cell dissociation and nuclear margin were determining features (p<0.005). Correlation between cytological grading and histological grading was statistically significant (p<0.005).Conclusion:  Robinson’s cytological grading is the easy grading method that can be done on cytology smears of the breast carcinoma to achieve relevant information regarding aggressiveness of the tumor and to plan for neoadjuvant chemotherapy preoperatively.

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