scholarly journals Lesions of the breast with uncertain malignant potential

2021 ◽  
Vol 17 (2) ◽  
pp. 46-57
Author(s):  
I. V. Vуsotskaya ◽  
I. A. Gladilina ◽  
V. Yu. Kirsanov ◽  
N. V. Ponedelnikova ◽  
E. A. Kim ◽  
...  
Keyword(s):  
Mammary Gland ◽  
Conservative Management ◽  
Subsequent Development ◽  
Malignant Potential ◽  
Aspiration Biopsy ◽  
Biological Behavior ◽  
Breast Diseases ◽  
Basic Information ◽  
Uncertain Malignant Potential ◽  
Vacuum Aspiration

The article deals with a peculiar group of breast diseases, which belongs to the B3 category according to the BI-RADS classification, the so-called lesions with undefined malignant potential. The basic information concerning their biological behavior and modern tactical approaches to the management of patients with similar changes in the mammary gland are presented. The possibility of conservative management, as well as the minimization of surgical aid, in cases of indications for it, up to vacuum aspiration biopsy is being considered. In addition, the significance of these diseases for the subsequent development of pre-invasive and infiltrative cancer is discussed.

scholarly journals Low-Grade Malignancy Glomus Tumor in a Setting of Multiple Glomus Tumors – Case Report

2019 ◽  
Vol 7 (23) ◽  
pp. 4082-4088
Author(s):  
Violeta Vasilevska-Nikodinovska ◽  
Milan Samardjiski ◽  
Rubens Jovanovik ◽  
Boro Ilievski ◽  
Vesna Janevska
Keyword(s):  
Glomus Tumor ◽  
Subcutaneous Tissue ◽  
Vena Cava ◽  
Malignant Potential ◽  
Biological Behavior ◽  
Low Grade ◽  
Uncertain Malignant Potential ◽  
Glomus Tumors ◽  
Small Nodule ◽  
Multiple Lesions

BACKGROUND: Glomus tumors are rare neoplasms accounting for less than 2% of all soft tissue tumors but multiple lesions may be seen in up to 10% of the patients. Solitary glomus tumor (GT) most frequently appears as small nodule in specific locations such as subungual region or deep dermis. However, rarely these entities have been observed in extracutaneous locations such as the gastrointestinal, cardiovascular, respiratory tracts, and other visceral organs. A small fraction of the GTs may present as tumors of uncertain malignant potential or as malignant glomus tumors. CASE PRESENTATION: We report a patient with multiple glomus tumors on the time of diagnosis, which was histologically diagnosed as an atypical glomus tumor following resection of a tumor thrombus in the left renal vein, inferior vena cava trombus with intracardial extension, and mitral valve specimen. The intramuscular lesion from the thigh was diagnosed as a glomus tumor of uncertain malignant potential. Further examinations revealed multiple lesions trough her body: kidneys, breast, heart and subcutaneous tissue. The diagnosis of glomus tumor of uncertain malignant potential versus glomus tumor with low malignant potential could be quite challenging, and the clinical course may be as a determining factor for final diagnosis. CONCLUSION: To our knowledge, this is the only known case of glomus tumor with multiple organ involvement and aggressive biological behavior at presentation.

scholarly journals Multimodal perioperative analgesia with minimally invasive interventions on the mammary gland

Pain medicine ◽  
2018 ◽  
Vol 3 (1) ◽  
pp. 43-46
Author(s):  
D. E. Korenyuk ◽  
A. G. Tkachuk ◽  
Yu. M. Terzi ◽  
V. Ya. Lagunov ◽  
A. G. Antonenko ◽  
...  
Keyword(s):  
Mammary Gland ◽  
Minimally Invasive ◽  
Postoperative Period ◽  
Breast Tissue ◽  
Pain Syndrome ◽  
Multimodal Analgesia ◽  
Aspiration Biopsy ◽  
Perioperative Analgesia ◽  
Vacuum Aspiration ◽  
Full Life

The article presents the study of the use of parenteral forms of drugs Infulgan and Nalbuphine on the base of the Regional Mammological Center and the Department of Anesthesiology N 1 of Clinical Oncology Dispensary (Dnipro). We have generalized the experience of using these agents as part of multimodal perioperative analgesia in 15 patients who underwent a vacuum aspiration biopsy of the mammary gland using the “Mammotome HH” device. We assessed the intensity of pain in the postoperative period and the need for additional anesthesia. The results of the study showed that the pre-emptive multimodal analgesia with the use of par cetamol in the form of an infusion of Nalbuphine was effective and safe for perioperative analgesia in outpatient minimally invasive diagnostic and therapeutic operations on breast tissue. Such anesthesia made it possible to reduce the doses of anaesthetics used in the postoperative period, facilitating the return of patients to a full life after breast vacuum aspiration biopsy. Our experience may be recommended for relief of the pain syndrome after minimally invasive surgery interventions.

Hardware for Mammary Gland Vacuum Aspiration Biopsy under X-Ray and Ultrasound Monitoring

2008 ◽  
Vol 42 (5) ◽  
pp. 265-268
Author(s):  
N. I. Rozhkova ◽  
G. P. Kochetova ◽  
M. L. Mazo
Keyword(s):  
Mammary Gland ◽  
Aspiration Biopsy ◽  
X Ray ◽  
Ultrasound Monitoring ◽  
Vacuum Aspiration

Large Oncocytic Adrenocortical Tumor with Uncertain Malignant Potential

2018 ◽  
Author(s):  
Betul Aydin Buyruk ◽  
Goknur Yorulmaz ◽  
Belgin Efe ◽  
Bartu Badak ◽  
Deniz Arik ◽  
...  
Keyword(s):  
Malignant Potential ◽  
Adrenocortical Tumor ◽  
Uncertain Malignant Potential

HISTOLOGICAL DIAGNOSTICS OF MAMMARY GLAND NEOPLASMS IN CATS

2020 ◽  
Keyword(s):  
Mammary Gland ◽  
Malignant Tumors ◽  
Breast Tumors ◽  
Domestic Animals ◽  
Breast Diseases ◽  
Microscopic Studies ◽  
Malignant Breast ◽  
Poorly Differentiated ◽  
Breast Adenocarcinomas

Mammary gland neoplasms in cats are at the top of the list of the most common nosological diseases among domestic animals; more than half of the tumors appear as malignant. Veterinary practitioners have many questions about the prevalence of breast tumors in cats, depending on age, breed and seasons of the year. The article presents the results of diseases prevalence of benign and malignant breast tumors in cats kept in the conditions of Bishkek. The characteristic of macroscopic and microscopic studies of benign and malignant breast tumors in cats at different periods of life and depending on the breed is also described. Studies were conducted in the period from March 2018 to March 2019. Morphological methods were used in the study of breast tumors. As a result of our research, we established the morphological forms of benign and malignant breast tumors in cats. Among benign neoplastic breast diseases in cats, breast lipoma was observed. Also among the malignant tumors of the breast met highly differentiated, moderately differentiated and poorly differentiated breast adenocarcinomas malnutrition and necrosis as well as the rare phylloid (leaf-shaped) fibroadenoma of the mammary gland which makes up only 0.3-0.5 % of all breast tumors.

Stanford parameters stratify the risk of recurrence in gynecologic smooth muscle tumors of uncertain malignant potential (STUMP)

Apmis ◽  
2021 ◽  
Author(s):  
Antonio Travaglino ◽  
Antonio Raffone ◽  
Annarita Gencarelli ◽  
Carola Caldarelli ◽  
Marcello Granata ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Malignant Potential ◽  
Uncertain Malignant Potential ◽  
Risk Of Recurrence ◽  
Smooth Muscle Tumors

Recurrent Prostatic Stromal Tumor of Uncertain Malignant Potential Combined with Concurrent Prostatic Adenocarcinoma: An Unusual Case

2021 ◽  
pp. 1-5
Author(s):  
Zhen Zhang ◽  
Chaozhao Liang
Keyword(s):  
Transurethral Resection ◽  
Unusual Case ◽  
Malignant Potential ◽  
Prostatic Adenocarcinoma ◽  
Stromal Tumor ◽  
Simultaneous Occurrence ◽  
Uncertain Malignant Potential ◽  
Unique Case ◽  
Neoplastic Lesions

Prostatic stromal tumor of uncertain malignant potential (STUMP), characterized by an atypical, unique stromal proliferation of the prostate, is often difficult to be differentiated from other nonepithelial neoplastic lesions. We present a unique case of recurrent STUMP after transurethral resection of the prostate (TURP) with concurrent prostatic adenocarcinoma. Patients diagnosed with prostatic STUMP should be followed up closely, for it may recur and invade adjacent organs after TURP shortly. Concurrent prostatic adenocarcinoma can be found in STUMP patients, and there may be some potential mechanisms which promote the simultaneous occurrence of the 2 tumors.

Unusual morphological features of uterine leiomyomas treated with progestogens

2011 ◽  
Vol 64 (6) ◽  
pp. 485-489 ◽  
Author(s):  
Clinton Boyd ◽  
W Glenn McCluggage
Keyword(s):  
Smooth Muscle ◽  
Mitotic Activity ◽  
Intrauterine Device ◽  
Malignant Potential ◽  
Morphological Features ◽  
Uterine Leiomyomas ◽  
Pathological Features ◽  
Uncertain Malignant Potential ◽  
Smooth Muscle Tumour ◽  
Benign Leiomyoma

BackgroundUterine leiomyomas are extremely common in surgical pathology practice and in the vast majority there are no issues in diagnosis. Progestogens are widely prescribed drugs for a variety of indications, including abnormal uterine bleeding, and are often given to women with leiomyomas but the pathological features of leiomyomas treated with progestogens are poorly described.MethodsWe report the pathological features in eight cases of uterine leiomyomas in women who had been treated with oral progestogens or a progestogen-containing intrauterine device; all cases were received in consultation because the features raised concern for leiomyosarcoma, smooth muscle tumour of uncertain malignant potential or a benign leiomyoma with unusual features. Additionally, we reviewed a series of cases of uterine leiomyomas (n=99) in women who exhibited progestogenic effects in the endometrium.ResultsThe morphological features in the consult cases, which were widespread and marked and which varied somewhat from case to case, included small and/or large areas of infarct-type necrosis (sometimes mimicking coagulative tumour cell necrosis) with surrounding increased cellularity, mitotic activity, nuclear pyknosis, cytoplasmic eosinophilia, epithelioid morphology, stromal oedema, haemorrhage, and myxoid change and infiltration by CD56 positive granulated lymphocytes. Sometimes the features resulted in an almost deciduoid appearance. Similar features were present to a minor degree in significant numbers of the additional series of cases.ConclusionsPathologists should be aware of these progestogen-associated features when reporting uterine leiomyomas whether or not the clinician has indicated that the woman is taking progestogens since otherwise a diagnosis of leiomyosarcoma or smooth muscle tumour of uncertain malignant potential may be rendered. Useful features in suggesting a benign leiomyoma, in addition to recognition of the morphological features described which, in combination, are characteristic of progestogens, are the lack of true nuclear atypia and the low mitotic activity away from the abnormal areas.

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