To the treatment of gastric ulcers

1927 ◽  
Vol 23 (9) ◽  
pp. 965-965
Author(s):  
E. Board
Keyword(s):  
Intravenous Injection ◽  
Intestinal Tract ◽  
Gastric Ulcers ◽  
Sugar Solution ◽  
Rapid Healing

A prerequisite for rapid healing of gastric ulcers is complete rest for both the stomach itself and the upper intestinal tract. To achieve this, Tillmann recommends feeding the patient exclusively by intravenous injection of grape sugar solution (5.00 per 1000.0 saline) for 10-12 days.

Treatment of purulent peritonitis

1927 ◽  
Vol 23 (5) ◽  
pp. 586-587
Author(s):  
A. Timofeev
Keyword(s):  
Intravenous Injection ◽  
Abdominal Cavity ◽  
Early Operation ◽  
Sugar Solution ◽  
Infectious Focus ◽  
Purulent Peritonitis

The author treats purulent peritonitis as follows: early operation is possible, and, if circumstances permit, it is useful to pre-prepare the patient with napertia, coffein, and intravenous injection of 20 cc. 40% grape sugar solution to reduce the danger of anesthesia to the heart; the site of the incision is chosen according to the localization of the process; the wound is lubricated with Peruvian balsam before opening the peritoneum; if peritonitis spills over, the abdominal cavity is flushed; if the infectious focus can be reliably turned off, drainage is not necessary; wire sutures. Careful stretching of rectal stomas after surgery facilitates the evacuation of gases and feces.

scholarly journals Probiotics, Prebiotics, and Synbiotics: Gut and Beyond

2012 ◽  
Vol 2012 ◽  
pp. 1-16 ◽  
Author(s):  
Usha Vyas ◽  
Natarajan Ranganathan
Keyword(s):  
Gut Microbiota ◽  
Intestinal Microbiota ◽  
Intestinal Tract ◽  
Gastric Ulcers ◽  
Colon Cancers ◽  
Bowel Diseases ◽  
Health And Disease ◽  
The Individual ◽  
And Control ◽  
Human Intestinal Tract

The human intestinal tract has been colonized by thousands of species of bacteria during the coevolution of man and microbes. Gut-borne microbes outnumber the total number of body tissue cells by a factor of ten. Recent metagenomic analysis of the human gut microbiota has revealed the presence of some 3.3 million genes, as compared to the mere 23 thousand genes present in the cells of the tissues in the entire human body. Evidence for various beneficial roles of the intestinal microbiota in human health and disease is expanding rapidly. Perturbation of the intestinal microbiota may lead to chronic diseases such as autoimmune diseases, colon cancers, gastric ulcers, cardiovascular disease, functional bowel diseases, and obesity. Restoration of the gut microbiota may be difficult to accomplish, but the use of probiotics has led to promising results in a large number of well-designed (clinical) studies. Microbiomics has spurred a dramatic increase in scientific, industrial, and public interest in probiotics and prebiotics as possible agents for gut microbiota management and control. Genomics and bioinformatics tools may allow us to establish mechanistic relationships among gut microbiota, health status, and the effects of drugs in the individual. This will hopefully provide perspectives for personalized gut microbiota management.

scholarly journals THE EXPERIMENTAL PRODUCTION OF NECROSIS OF THE LIVER IN THE GUINEA PIG

1914 ◽  
Vol 20 (2) ◽  
pp. 169-179 ◽  
Author(s):  
Moyer S. Fleisher ◽  
Leo Loeb
Keyword(s):  
Guinea Pig ◽  
Intravenous Injection ◽  
Liver Cells ◽  
Gastric Ulcers ◽  
Toxic Substances ◽  
Experimental Production ◽  
Mechanical Factors

Through the intravenous injection of various substances differing very much in character, multiple necrosis can be produced in the liver of the guinea pig. In the mouse the effect of these substances is absent or much less marked. Different substances seem to differ, however, in their power to produce necrosis. In control animals necrosis in the liver is much more rare. It is found especially in animals subjected to various injurious influences. The necrotic areas are usually situated between the portal and central areas of the liver acini. Their development is not due to thromboses interfering with the circulation in certain areas of the liver. They are probably due to a weakening of the circulation in the liver or to interference with the metabolism of the cells as a result of the injection of foreign substances. Mechanical factors (pressure on the liver cells) may have an additional effect. This necrosis may be compared etiologically to the acute gastric ulcers which can be produced through a great variety of toxic substances in the guinea pig.

Rapid healing of gastric ulcers with lansoprazole

2007 ◽  
Vol 8 (2) ◽  
pp. 215-220 ◽  
Author(s):  
K. D. BARDHAN ◽  
J. AHLBERG ◽  
W. S. HISLOP ◽  
C. LINDHOLMER ◽  
R. G. LONG ◽  
...  
Keyword(s):  
Gastric Ulcers ◽  
Rapid Healing

scholarly journals Cost-Effectiveness of Intravenous Proton Pump Inhibitors in High-Risk Bleeders

2004 ◽  
Vol 18 (12) ◽  
pp. 749-750
Author(s):  
Sander Veldhuyzen van Zanten
Keyword(s):  
Cost Effectiveness ◽  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Gastric Ulcers ◽  
Recurrent Bleeding ◽  
Gi Bleeding ◽  
H2 Blockers ◽  
Rapid Healing ◽  
Upper Gastrointestinal

There is unequivocal evidence that proton pump inhibitors (PPIs) are currently the most effective acid suppressive agents available. Intravenous (IV) formulations have been developed, although only IV pantoprazole is available in Canada. In patients presenting with serious upper gastrointestinal (GI) bleeding due to duodenal or gastric ulcers, it has always been believed that IV administration of acid-lowering agents would improve clinical outcomes. The reason behind this thinking is twofold. First, there is in vitro evidence that formed clots are more stable at or near neutral pH (1). Second, by administering the agent intravenously, suppression of acid production is achieved much more quickly, thereby promoting more rapid healing of the ulcer and reducing the risk of persistent or recurrent bleeding. Interestingly and surprisingly, however, the data for intravenous H2-blockers have been disappointing (2). This failure to demonstrate clinical benefit has never been fully explained.

Electron Microscopic Detection and Characterization of Nonhuman Primate Enteric Viruses

1982 ◽  
Vol 40 ◽  
pp. 306-307
Author(s):  
G. C. Smith ◽  
R. L. Heberling ◽  
S. S. Kalter
Keyword(s):  
Electron Microscopy ◽  
Animal Model ◽  
Nonhuman Primate ◽  
Clinical Condition ◽  
Intestinal Tract ◽  
Enteric Viruses ◽  
Electron Microscopic ◽  
Microscopic Detection

A number of viral agents are recognized as and suspected of causing the clinical condition “gastroenteritis.” In our attempts to establish an animal model for studies of this entity, we have been examining the nonhuman primate to ascertain what viruses may be found in the intestinal tract of “normal” animals as well as animals with diarrhea. Several virus types including coronavirus, adenovirus, herpesvirus, and picornavirus (Table I) were detected in our colony; however, rotavirus, astrovirus, and calicivirus have not yet been observed. Fecal specimens were prepared for electron microscopy by procedures reported previously.

Gastric Ulcers Produced by Cisplatin

1981 ◽  
Vol 39 ◽  
pp. 582-583
Author(s):  
S.K. Aggarwal ◽  
J. San Antonio
Keyword(s):  
Electron Microscopy ◽  
Single Dose ◽  
Side Effects ◽  
Antitumor Agent ◽  
Gastric Ulcers ◽  
Enzyme Cytochemistry ◽  
Intestinal Toxicity ◽  
Ovarian Cancers ◽  
Inner Surface

Cisplatin (cis-dichlorodiammineplatinum(II)) a potent antitumor agent is now available for the treatment of testicular and ovarian cancers. It is however, not free from its serious side effects including nephrotoxicity, gastro intestinal toxicity, myelosuppression, and ototoxicity. Here we now report that the drug produces peculiar bloating of the stomach in rats and induces acute ulceration.Wistar-derived rats weighing 200-250 g were administered cisplatin(9 mg/kg) ip as a single dose in 0.15 M NaCl. After 3 days the animals were sacrificed by decapitation. The stomachs were removed, the contents analyzed for pepsin and acidity. The inner surface was examined with a dissecting microscope after a moderate stretching for ulcers. Affected areas were fixed and processed for routine electron microscopy and enzyme cytochemistry.The drug treated animals kept on food and water consistently showed bloating and lesions (Fig. 1) with a frequency of 6-70 ulcers in the rumen section of the stomachs.

Activation of isolated heterophils from chicks stimulated in vivo with salmonella enteritidis-immune lymphokines

1996 ◽  
Vol 54 ◽  
pp. 760-761
Author(s):  
R. B. Moyes ◽  
R. E. Droleskey ◽  
M. H. Kogut ◽  
J. R. DeLoach
Keyword(s):  
Lamina Propria ◽  
Intestinal Mucosa ◽  
Salmonella Enteritidis ◽  
Intestinal Tract ◽  
Polymorphonuclear Cells ◽  
Subclinical Infection ◽  
Egg Products ◽  
Immune Lymphokines ◽  
Organ Invasion

Salmonella enteritidis (SE) is of great concern to the poultry industry due to the organism's ability to penetrate the intestinal mucosa of the laying hen and subsequently colonize the ovaries and yolk membrane. The resultant subclinical infection can lead to SE infection of raw eggs and egg products. Interference with the ability of the organism to invade has been linked to the activation and recruitment of inflammatory polymorphonuclear cells, heterophils, to the lamina propria of the intestinal tract.Recently it has been established that heterophil activation and increased resistance to SE organ invasion can be accomplished by the administration of SE-immune lymphokines (SE-ILK) obtained from supernatants of concanavalin-A stimulated SE immune T lymphocytes from SE hyperimmunized hens. Invasion of SE into the lamina propria provides a secondary signal for directing activated heterophils to the site of SE invasion.

Effects of antisecretory agents on anglogenesis during healing of gastric ulcers

2001 ◽  
Vol 120 (5) ◽  
pp. A148-A148 ◽  
Author(s):  
M AKIMOTO ◽  
H HASHIMOTO ◽  
A MAEDA ◽  
M SHIGEMOTO ◽  
K YAMASHITA
Keyword(s):  
Gastric Ulcers
Sign in / Sign up

Export Citation Format

Share Document