scholarly journals Treatment of purulent peritonitis

2021 ◽  
Vol 22 (9) ◽  
pp. 1073-1073
Author(s):  
V. Gruzdev
Keyword(s):  

This question was programmatic for what happened in April like this. Years of the 50th Congress of German Surgeons.

1993 ◽  
Vol 74 (2) ◽  
pp. 155-158
Author(s):  
Yu. V. Bondarev ◽  
R. A. Zulkarneev ◽  
O. D. Zinkevich ◽  
A. H. Chugunov ◽  
N. A. Safina

Currently, some progress has been achieved in the treatment of diffuse purulent peritonitis (RP), associated with the use of new antibiotics and their routes of administration (intraperitoneal, endolymphatic, lymphotropic), as well as with the use of hemosorption and plasmapheresis. Nevertheless, mortality in this pathology is still quite high and, according to our observations, is 50-60%, which is largely due to pronounced endogenous intoxication. In turn, the latter leads to inhibition of the absorptive function of the liver and spleen, which may be associated with the functional state of macrophages of these organs and with a deficiency of opsonic factors due to their consumption.


1927 ◽  
Vol 23 (8) ◽  
pp. 847-848
Author(s):  
A. Timofeev
Keyword(s):  

The treatment of acute purulent peritonitis was discussed as a program issue at the last meeting of German Surgeons.


2013 ◽  
Vol 21 (5) ◽  
pp. 50-57 ◽  
Author(s):  
A.B. Larichev ◽  
◽  
E.J. Pokrovskij ◽  
A.A. Dylenok ◽  
◽  
...  

Author(s):  
S. A. Ruziboev ◽  
◽  
A. A. Avazov ◽  
Sh. Kh. Sattarov ◽  
A. N. Elmuradov ◽  
...  

Currently, despite significant achievements in the field of surgery, anesthesiology and resuscitation, the results of treatment of patients with advanced purulent peritonitis remain one of the most intractable problems, almost every sixth patient with acute surgical diseases and injuries of the abdominal cavity is admitted to medical institutions with peritonitis [1,3] Common peritonitis in 17-29% complicates the course of most acute surgical diseases and is the main cause of deaths in surgical hospitals [3,7]. Lethality in advanced peritonitis remains extremely high and reaches 20-39% [1,2,4,5]. In recent decades, great importance has been attached to recording intra-abdominal pressure in purulent pathology of the abdominal cavity. It was found that intra-abdominal hypertension occurs in every third patient with acute surgical pathology and negatively affects the functioning of all organs and systems of the body [1,6,8]. Pathological changes that occur with acute and excessive increase in intra-abdominal pressure (IAP) are manifestations of abdominal compartment syndrome (ACS) with disorders of the cardiovascular system; urinary disorders, disorders of perfusion of internal organs and the development of intestinal ischemia, which contributes to bacterial translocation and endogenous infection [2,7,8]. Ischemic blood flow disorders of the splanchnic zone are fraught with the development of bacterial translocation and the development of systemic inflammatory response syndrome and multiple organ failure (PON). Unsatisfactoriness with such results gave rise to a fundamentally different approach to the surgical treatment of common forms of peritonitis-the introduction of an open abdominal management method based on the ideas of I. Mikulich (1881), Jean-Louis Faure (1928), N. S. Makoch (1984) and D. Steinberg (1979).


2014 ◽  
Vol 69 (5-6) ◽  
pp. 23-28 ◽  
Author(s):  
A.A. Savchenko ◽  
◽  
D.E. Zdzitovetskiy ◽  
A.G. Borisov ◽  
N.A. Luzan ◽  
...  

2019 ◽  
Vol 9 (3-4) ◽  
pp. 539-548
Author(s):  
A. A. Savchenko ◽  
A. G. Borisov ◽  
I. V. Kudryavcev ◽  
V. D. Belenjuk

Our study was aimed at investigating dynamic phenotype pattern of peripheral blood NK cells in patients with widespread purulent peritonitis (WPP) during postoperative period depending on disease outcome. A total of 48 patients aged 30–63 with acute surgical diseases and abdominal injuries complicated by WPP were examined. Blood sampling was performed before surgery (preoperative period) as well as on day 7, 14 and 21 during postoperative period. 40 apparently healthy age-matched subjects were included in control group. Peripheral blood NK cell phenotyping was performed by using flow cytometry with directly immunofluorescently tagged antibodies. Mean fluorescence intensity was measured to estimate expression levels of NK cell surface receptors was measured. It was found that in patients with a favorable WPP outcome during preoperative period the percentage of mature NK cells was decreased that was restored by the end of the postoperative period (21 days post-surgery) due to elevated mature, cytotoxic and cytokine-producing NK cell subsets. In addition, percentage of CD11b-positive NK cell subsets was increased upon favorable outcome by the end of postoperative period as well as frequency of CD57-positive NK cells relative to the preoperative period. However, frequency of mature NK cells with unfavorable WPP outcome vs. control vs. favorable outcome was decreased during preoperative and entire postoperative period. Moreover, amount of cytotoxic NK cells was elevated during examination period upon unfavorable WPP outcome. Further, percentage of mature CD11b-positive NK cells in this patient cohort was decreased during preoperative period and post-surgery. Percentage of CD57-positive NK cells was decreased during entire postoperative period in patients with unfavorable vs. favorable outcome vs. control group. At the same time, patients with unfavorable outcome of this infectious-inflammatory disease were shown to display upregulated expression of CD28 and CD57 markers on NK cells. such features identified in phenotype of peripheral blood NK cells in patients with unfavorable WPP outcome reflect abnormal mechanisms in NK cell maturation and migration, which, in turn, determines disturbance in events regulating acute inflammatory reaction in WPP. 


1927 ◽  
Vol 23 (2) ◽  
pp. 264-265

Can purulent peritonitis follow as a consequence of abortion, without any changes in uterus and parameters? M. Klyachkin.Answer. This question should be answered negatively. Prof. V. Gruzdev.


1927 ◽  
Vol 23 (5) ◽  
pp. 586-587
Author(s):  
A. Timofeev

The author treats purulent peritonitis as follows: early operation is possible, and, if circumstances permit, it is useful to pre-prepare the patient with napertia, coffein, and intravenous injection of 20 cc. 40% grape sugar solution to reduce the danger of anesthesia to the heart; the site of the incision is chosen according to the localization of the process; the wound is lubricated with Peruvian balsam before opening the peritoneum; if peritonitis spills over, the abdominal cavity is flushed; if the infectious focus can be reliably turned off, drainage is not necessary; wire sutures. Careful stretching of rectal stomas after surgery facilitates the evacuation of gases and feces.


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