Intravenous and combined methods of treatment of articular rheumatism

In recent years, we have used the following methods in the treatment of articular rheumatism: 1) intravenous infusion of the so-called Attritin 16% salicylic sodium solution + 4% coffeini n.- salic solution. 2) Intramuscular injections of milk in combination with intravenous infusions of Attritin'a. 3) Intravenous infusion of opsonized salicylic sodium and 4) Natr. salic, ex 10-12.0-200.0 per os - 4-6 tablespoons per day in combination with subcutaneous injections of autologous blood.

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Rapidly Administered Hypertonic Solutions

PEDIATRICS ◽

10.1542/peds.47.1.154 ◽

1971 ◽

Vol 47 (1) ◽

pp. 154-154

Author(s):

Robert L. Harris

Keyword(s):

Total Dose ◽

Intravenous Infusion ◽

Human Organism ◽

Physiological Changes ◽

Valuable Addition ◽

Hypertonic Solutions ◽

Intravenous Infusions ◽

Clinically Significant

The article "Clinically Significant Physiological Changes from Rapidly Administered Hypertonic Solutions: Acute Osmol Poisoning" (Pediatrics, 46:267, 1970) by Kravath, et al. is a valuable addition to the pediatric literature. In a series of interesting experiments the authors again document the potential dangers of rapid intravenous infusions of hypertonic solutions. However, the implication that the experiments so performed are necessarily applicable inthe human organism need some clarification. In considering the effects of an intravenous infusion in the human, three factors should be considered: (1) osmoiality, (2) volume, and (3) total dose.

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About the method of treatment of gonorrhea and its complications according to the method of O. Sachs'a

Kazan medical journal ◽

10.17816/kazmj49984 ◽

1930 ◽

Vol 26 (2) ◽

pp. 177-181

Author(s):

С. Yu. Rothstein

Keyword(s):

Intravenous Infusion ◽

Psoriasis Vulgaris ◽

Combined Treatment ◽

Local Therapy ◽

Average Amount ◽

Duration Of Treatment ◽

Complete Cure ◽

Intravenous Infusions ◽

First Time ◽

Number Of Injections

O. Sachs, who for the first time proposed intravenous infusion of 20% sterile salicylic pagra solution for the treatment of psoriasis vulgaris, recommends this method to be used in the treatment of gonorrhea, especially its complications. In total, he conducted 103 cases of gonorrhoid urethritis in this way, in the overwhelming number complicated by epididymitis, funiculitis and prostatitis. In 72 patients, he used exclusively intravenous infusions of salicylic sodium, and in the rest, he also used local therapy before, during and after the infusions. He received excellent results from this method of treatment. Out of 72 patients who used only intravenous infusions of salicylic sodium, complete cure was achieved in 39 cases (54.16%), improvement in 32 cases (44.44%), and a negative result in only one. The duration of treatment on average was 21.5 days, each patient had 6.5 injections, with an average amount of salicylic sodium administered in 18.9 grams. With combined treatment, the percentage of complete cure increases even more, but with a larger number of injections and a longer duration period of treatment.

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Impermeability of the Blood—Cerebrospinal Fluid Barrier for Angiotensin II in Rats

Clinical Science ◽

10.1042/cs051399s ◽

1976 ◽

Vol 51 (s3) ◽

pp. 399s-402s ◽

Cited By ~ 7

Author(s):

P. Schelling ◽

J. S. Hutchinson ◽

U. Ganten ◽

G. Sponer ◽

D. Ganten

Keyword(s):

Cerebrospinal Fluid ◽

Angiotensin Ii ◽

Intravenous Infusion ◽

Ventricular System ◽

Cisterna Magna ◽

Biochemical Methods ◽

Intravenous Infusions ◽

Artificial Cerebrospinal Fluid ◽

Brain Ventricular System ◽

The Brain

1. Anaesthetized, nephrectomized rats were infused intravenously with unlabelled angiotensin II (AII) or with [3H]angiotensin II (3H-labelled AII). The brain ventricular system was perfused with artificial cerebrospinal fluid. The perfusate was collected from the cisterna magna and analysed for AII by radioimmunological and biochemical methods. 2. No increase of immunoreactive AII in cerebrospinal fluid could be shown during intravenous infusion of AII. 3. During intravenous infusions of 3H-labelled AII at pressor doses small amounts of radioactivity were found in cerebrospinal fluid perfusate. 4. The radioactivity of cerebrospinal fluid outflow could not be related to AII.

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INHIBITION BY DEXAMETHASONE OF ADRENOCORTICOTROPHIN AND CORTISOL RELEASE INDUCED BY INTRAVENOUS INFUSION OF ATP AND DIBUTYRYL CYCLIC AMP IN PIGLETS

Journal of Endocrinology ◽

10.1677/joe.0.0600065 ◽

1974 ◽

Vol 60 (1) ◽

pp. 65-73 ◽

Cited By ~ 5

Author(s):

D. B. COOK ◽

G. V. GILL ◽

I. M. D. JACKSON ◽

G. A. SMART

Keyword(s):

Cyclic Amp ◽

Intravenous Infusion ◽

Similar Pattern ◽

Plasma Cortisol ◽

Dibutyryl Cyclic Amp ◽

Plasma Acth ◽

Intravenous Infusions ◽

Consistent Increase ◽

Cortisol Release ◽

Corticosteroid Response

SUMMARY The effect of intravenous infusions of ATP and dibutyryl cyclic AMP (DB cyclic AMP) on adrenocorticotrophin (ACTH) and corticosteroid release was investigated in piglets. A consistent increase of both plasma ACTH and plasma cortisol was observed in response to infusions of 600 mg ATP/h. These responses were abolished by pretreating the animals with dexamethasone. A similar pattern of response was observed with DB cyclic AMP infused intravenously. No response occurred when 100 mg DB cyclic AMP were infused in 1 h, but there was a marked plasma corticosteroid response to an infusion of 600 mg DB cyclic AMP in 1 h. Surprisingly, this response was also abolished by pretreatment with dexamethasone.

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Equivalent Analgesia and Side Effects during Epidural and Pharmacokinetically Tailored Intravenous Infusion with Matching Plasma Alfentanil Concentration

Anesthesiology ◽

10.1097/00000542-199901000-00015 ◽

1999 ◽

Vol 90 (1) ◽

pp. 98-108 ◽

Cited By ~ 21

Author(s):

Barbara A. Coda ◽

Mary Cleveland Brown ◽

Linda BS Risler ◽

Karen Syrjala ◽

Danny D. Shen

Keyword(s):

Side Effects ◽

Intravenous Administration ◽

Intravenous Infusion ◽

Test Battery ◽

Systemic Absorption ◽

Subjective Rating ◽

Intravenous Infusions ◽

Upper And Lower Extremities ◽

Intravenous Saline ◽

End Tidal

Background Recently, several clinical studies comparing intravenous and epidural infusions of fentanyl and its derivatives suggested that epidural infusions act primarily by systemic absorption to produce supraspinal analgesia. To evaluate this hypothesis, the authors used pharmacokinetically tailored intravenous infusions to produce matching plasma alfentanil concentrations during epidural and intravenous administration. The analgesia and side effects achieved with each mode of administration were compared. Methods Twelve volunteers participated in this placebo-controlled crossover study. The pain model was cutaneous electric stimulation of the finger and toe. The test battery included subjective rating of pain intensity; end-tidal carbon dioxide level; pupil size; ratings of alertness, nausea, and pruritus; and a plasma alfentanil assay. On one test day, the participants received epidural alfentanil (400 microg bolus + a 400-microg/h infusion for 2 h) and an intravenous saline infusion. The test battery was administered at regular intervals. On another test day, the participants received epidural saline and a computer-controlled intravenous infusion of alfentanil. The testing protocol was repeated as on the first test day. On the day the placebo was administered, the participants received epidural and intravenous saline infusions. The order of the placebo day was randomized. Results Plasma alfentanil concentration-time profiles were identical during epidural and intravenous infusions. A nearly equivalent analgesic response was observed with epidural and intravenous alfentanil at the upper and lower extremities. There were no differences in side effects for epidural and intravenous administration. Conclusions The systemic redistribution of alfentanil accounts for most of the analgesia and effects produced by epidural infusion.

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Autohemotherapy as a Reiztherapie method for rheumatic, articular and some gynecological diseases

Kazan medical journal ◽

10.17816/kazmj79292 ◽

1929 ◽

Vol 25 (5) ◽

pp. 519-525

Author(s):

A. A. Opokin ◽

R. I. Zak

Keyword(s):

Rheumatic Diseases ◽

Combined Treatment ◽

Combined Method ◽

The Press ◽

Gynecological Diseases ◽

Mud Therapy ◽

Methods Of Treatment ◽

Combined Methods

The interest in the combined methods of treatment for mud therapy began to be debated in the press, at congresses and in societies relatively recently. On the question of so. called Duplication of procedures, the opinions of the authors still differ. Much attention is paid to the combined method for mud therapy in some of our Russian mud cure resorts; Thus, at the Kuyalnitsky estuary, with the participation of Professor EM Brusilovsky, even special schemes for the combined treatment of rheumatic diseases were created (Doctor, Delo, 1926, No. 9. Department of Consulting Practice).

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To the question of the comparative assessment of various combined methods of treatment of chronic polyarthritis

Kazan medical journal ◽

10.17816/kazmj79295 ◽

1929 ◽

Vol 25 (5) ◽

pp. 526-531

Author(s):

М. N. Gremyachkin ◽

N. V. Zhukovskaya

Keyword(s):

Therapeutic Effect ◽

Combined Treatment ◽

Comparative Assessment ◽

Chronic Polyarthritis ◽

Spa Treatment ◽

Methods Of Treatment ◽

Combined Methods

Combined methods of treating chronic polyarthritis means a combination of balneological procedures (sulfuric and mud baths) with pharmaco or physiotherapeutic agents, that is, simultaneous carrying out of two or more methods of treatment. The purpose of the combined treatment is, first of all, the intensification of spa treatment, that is, an increase in the therapeutic effect of natural spa factors and, as a consequence, a reduction in the period of spa treatment of patients and an increase in bed turnover (Brusilovsky).

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Recombinant human endostatin administered as a 28-day continuous intravenous infusion, followed by daily subcutaneous injections: a phase I and pharmacokinetic study in patients with advanced cancer

Annals of Oncology ◽

10.1093/annonc/mdi318 ◽

2005 ◽

Vol 16 (10) ◽

pp. 1695-1701 ◽

Cited By ~ 45

Author(s):

A.H.G. Hansma ◽

H.J. Broxterman ◽

I. van der Horst ◽

Y. Yuana ◽

E. Boven ◽

...

Keyword(s):

Phase I ◽

Advanced Cancer ◽

Pharmacokinetic Study ◽

Intravenous Infusion ◽

Continuous Intravenous Infusion ◽

Recombinant Human Endostatin ◽

Subcutaneous Injections

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On the issue of comparative assessment of various combined methods of treatment of chronic polyarthritis

Kazan medical journal ◽

10.17816/kazmj83672 ◽

1929 ◽

Vol 25 (5) ◽

pp. 525-530

Author(s):

M. N. Gremyachkin ◽

N. V. Zhukovsky

Keyword(s):

Therapeutic Effect ◽

Combined Treatment ◽

Comparative Assessment ◽

Chronic Polyarthritis ◽

Spa Treatment ◽

Methods Of Treatment ◽

Combined Methods

Combined methods of treating chronic polyarthritis means a combination of balneological procedures (sulfuric and mud baths) with pharmaco or physiotherapeutic agents, that is, simultaneous carrying out of two or more methods of treatment. The purpose of the combined treatment is, first of all, the intensification of spa treatment, i.e., an increase in the therapeutic effect of natural spa factors and, as a consequence, a reduction in the period of spa treatment of patients and an increase in bed turnover (Brusilovsky)

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