Clinicopathogenetic features of cardiovascular system affection in influenza patients with hypertensive reaction revealed for the first time

Aim. To study the state of central hemodynamics, oxygen metabolism and tissue blood flow in patients with influenza who suffered from hypertensive reaction detected for the first time, in dynamics of infectious process. Materials and methods. At Perm Regional Clinical Infectious Hospital, 65 patients with influenza underwent a deepened study of cardiovascular system: central hemodynamics and local blood flow. Results. While studying the central hemodynamics, there was detected the increased general peripheric vascular resistance without normalization during the follow-up period. Investigation of gas exchange showed decrease in tissue oxygenation, vasodilatation and tissue blood flow. Conclusions. Among patients with influenza, the oxygen transport system functions in a tense regime. In dynamics of infectious process and after the disease, the following is observed: development of tissue hypoxia, decrease in local blood flow tempo and elevation of general peripheric vascular resistance.

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Local Blood Flow and Oxygen Metabolism in Glioma and Its Surrounding Brain

Brain Edema ◽

10.1007/978-3-642-70696-7_41 ◽

1985 ◽

pp. 267-272 ◽

Cited By ~ 2

Author(s):

W. Taki ◽

H. Handa ◽

M. Ishikawa ◽

A. Kobayashi ◽

J. Yamashita ◽

...

Keyword(s):

Blood Flow ◽

Oxygen Metabolism ◽

Local Blood Flow

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Portable Near-Infrared Technologies and Devices for Noninvasive Assessment of Tissue Hemodynamics

Journal of Healthcare Engineering ◽

10.1155/2019/3750495 ◽

2019 ◽

Vol 2019 ◽

pp. 1-11 ◽

Cited By ~ 3

Author(s):

Lin Hou ◽

Yinqiu Liu ◽

Lixia Qian ◽

Yucong Zheng ◽

Jinnan Gao ◽

...

Keyword(s):

Blood Flow ◽

Flow Measurement ◽

Near Infrared ◽

Tissue Oxygenation ◽

Oxygen Metabolism ◽

Correlation Spectroscopy ◽

Tissue Blood Flow ◽

Diffuse Optical Spectroscopy ◽

Diffuse Correlation Spectroscopy ◽

Custom Made

Tissue hemodynamics, including the blood flow, oxygenation, and oxygen metabolism, are closely associated with many diseases. As one of the portable optical technologies to explore human physiology and assist in healthcare, near-infrared diffuse optical spectroscopy (NIRS) for tissue oxygenation measurement has been developed for four decades. In recent years, a dynamic NIRS technology, namely, diffuse correlation spectroscopy (DCS), has been emerging as a portable tool for tissue blood flow measurement. In this article, we briefly describe the basic principle and algorithms for static NIRS and dynamic NIRS (i.e., DCS). Then, we elaborate on the NIRS instrumentation, either commercially available or custom-made, as well as their applications to physiological studies and clinic. The extension of NIRS/DCS from spectroscopy to imaging was depicted, followed by introductions of advanced algorithms that were recently proposed. The future prospective of the NIRS/DCS and their feasibilities for routine utilization in hospital is finally discussed.

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Role of EDRF in the regulation of regional blood flow and vascular resistance at rest and during exercise in conscious dogs

Journal of Applied Physiology ◽

10.1152/jappl.1994.77.1.165 ◽

1994 ◽

Vol 77 (1) ◽

pp. 165-172 ◽

Cited By ~ 59

Author(s):

W. Shen ◽

M. Lundborg ◽

J. Wang ◽

J. M. Stewart ◽

X. Xu ◽

...

Keyword(s):

Blood Flow ◽

Vascular Resistance ◽

Skeletal Muscles ◽

Acute Exercise ◽

Regional Blood Flow ◽

Conscious Dogs ◽

Tissue Blood Flow ◽

Minor Role ◽

Blood Flows ◽

A Minor

The contribution of endothelium-derived relaxing factor (EDRF) to the regulation of regional vascular resistance and tissue blood flow at rest and during acute moderate exercise was studied in chronically instrumented conscious dogs. Radioactive microspheres were injected before and during exercise to measure regional blood flow. An infusion of nitro-L-arginine (L-NA), an analogue of L-arginine, was used to inhibit the synthesis of EDRF and resulted in a significant increase in mean arterial pressure, associated with significantly elevated vascular resistance in heart, skeletal muscle, renal and splanchnic circulations and with decreases in tissue blood flow in those regions at rest. Acute exercise caused a typical redistribution of blood flow, in which there was vasodilation in heart and working skeletal muscles, accompanied by vasoconstriction in kidney and splanchnic circulations. L-NA resulted in significantly elevated vascular resistance during vasodilation in heart and working skeletal muscles and also significantly increased vasoconstriction in renal cortex, stomach, pancreas, liver, and colon during exercise. Blood flows during exercise were largely unaffected by L-NA treatment. Our results suggest that whereas EDRF functions to regulate basal vascular tone and vascular resistance during exercise, EDRF has a minor role in determining the pattern of the redistribution of tissue blood flow during exercise.

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Cerebral blood flow, vascular resistance, and oxygen metabolism in acute brain trauma

Critical Care Medicine ◽

10.1097/00003246-199508000-00016 ◽

1995 ◽

Vol 23 (8) ◽

pp. 1412-1417 ◽

Cited By ~ 72

Author(s):

Julio Cruz ◽

Jurg L. Jaggi ◽

Ole J. Hoffstad

Keyword(s):

Blood Flow ◽

Cerebral Blood Flow ◽

Vascular Resistance ◽

Oxygen Metabolism ◽

Brain Trauma

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AGE-INDUCED ALTERATIONS OF BONE TISSUE BLOOD FLOW AND VASCULAR RESISTANCE IN FISCHER 344 RATS

Medicine & Science in Sports & Exercise ◽

10.1097/00005768-199805001-01669 ◽

1998 ◽

Vol 30 (Supplement) ◽

pp. 293

Author(s):

S. A. Bloomfield ◽

M. D. Delp

Keyword(s):

Blood Flow ◽

Bone Tissue ◽

Vascular Resistance ◽

Tissue Blood Flow ◽

Fischer 344 Rats ◽

Fischer 344

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Comparative characteristics of changes in central hemodynamics during early recovery after different exercise regimes

Reports of Morphology ◽

10.31393/morphology-journal-2021-27(2)-07 ◽

2021 ◽

Vol 27 (2) ◽

pp. 47-52

Author(s):

H.V. Lukyantseva ◽

O.M. Bakunovsky ◽

S.S. Malyuga ◽

T.M. Oliinyk ◽

N.R. Manchenko ◽

...

Keyword(s):

Blood Pressure ◽

Cardiovascular System ◽

Dynamic Loading ◽

Vascular Resistance ◽

Dynamic Load ◽

Static Loading ◽

Circulatory System ◽

The Body ◽

Central Hemodynamics ◽

Early Recovery

The cardiovascular system is one of the most important functional systems of the body, which determine the level of physical performance of the body. Insufficient study of the response of the circulatory system to the combination of strength training with endurance exercises requires more detailed comparative studies of the impact of dynamic and static loads on the indicators of central hemodynamics. Accordingly, the aim of our study was to study the characteristics of the reaction of the cardiovascular system in the period of early recovery after dosed exercise of a dynamic and static nature. The study examined the response of the central hemodynamics of young men in the period of early recovery after dynamic loading (Martine functional test) and static loading (holding on the stand dynamometer DS-200 force with a power of 50% of maximum standing force). The change in circulatory system parameters was recorded using a tetrapolar thoracic impedance rheoplethysmogram on a computerized diagnostic complex “Cardio +”. It is established that the dynamic load in the period of early recovery does not cause a significant positive chronotropic effect, leads to a decrease in vascular resistance of blood flow, to an increase in pulse blood pressure. The increase in cardiac output is mainly due to the increase in stroke volume, which indicates a fairly high functional reserves of the heart. It is revealed that under conditions of static loading the reaction of central hemodynamics and the course of early recovery are radically different from the changes of indicators under dynamic loading. In persons with a normodynamic type of reaction to dynamic load, there are no significant changes in the minute volume of blood at a similar volume of active muscle mass static load. Meeting the metabolic needs of working skeletal muscles and compensating for the oxygen debt is realized by increasing the total peripheral vascular resistance and increasing systolic blood pressure in the postpartum period. The physiological meaning of this phenomenon is to maintain a sufficient level of venous return of blood to ensure the pumping function of the heart.

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Microvascular rarefaction and tissue vascular resistance in hypertension

AJP Heart and Circulatory Physiology ◽

10.1152/ajpheart.1989.256.1.h126 ◽

1989 ◽

Vol 256 (1) ◽

pp. H126-H131 ◽

Cited By ~ 51

Author(s):

A. S. Greene ◽

P. J. Tonellato ◽

J. Lui ◽

J. H. Lombard ◽

A. W. Cowley

Keyword(s):

Blood Flow ◽

Vascular Resistance ◽

Total Peripheral Resistance ◽

Peripheral Resistance ◽

Flow Distribution ◽

Cheek Pouch ◽

Tissue Blood Flow ◽

Hamster Cheek Pouch ◽

Relative Contribution ◽

Microvascular Rarefaction

The purpose of this study was to quantitatively estimate the relative contribution of arteriolar rarefaction (disappearance of microvessels) and arteriolar constriction to the increases in total peripheral resistance and changes in the patterns of flow distribution observed in hypertension. A mathematical model of the hamster cheek pouch intraluminal microcirculation was constructed based on data from the literature and observations from our own laboratory. Separate rarefaction and constriction of third-order (3A) and fourth-order (4A) arterioles were performed on the model, and the results were quantified based on the changes of the computed vascular resistance. The degree of increase in resistance depended both on the number and the order of vessels rarefied or constricted and also on the position of those vessels in the network. The maximum increases in resistance obtained in the model runs were 21% for rarefaction and 75% for constriction. Rarefaction, but not constriction, produced large increases in the degree of heterogeneity of blood flow in the various vessel orders. These results demonstrate that vessel rarefaction significantly influences tissue blood flow resistance to a degree comparable with vessel constriction; however, unlike constriction, microvascular rarefaction markedly altered blood flow distribution in our model of the hamster cheek pouch vascular bed. These findings conform with the hypothesis that a significant component of the increase in total peripheral resistance in hypertension may be due to vessel rarefaction.

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Influence of circulating NE and Epi on adipose tissue vascular resistance and lipolysis in humans

AJP Heart and Circulatory Physiology ◽

10.1152/ajpheart.1983.245.3.h447 ◽

1983 ◽

Vol 245 (3) ◽

pp. H447-H452 ◽

Cited By ~ 5

Author(s):

P. Hjemdahl ◽

B. Linde

Keyword(s):

Blood Flow ◽

Adipose Tissue ◽

Vascular Resistance ◽

Plasma Insulin ◽

Human Adipose Tissue ◽

Venous Occlusion ◽

Tissue Blood Flow ◽

Adipose Tissue Blood Flow ◽

Arterial Plasma ◽

Subcutaneous Adipose

The effects of circulating norepinephrine (NE) and epinephrine (Epi) on vascular resistance in subcutaneous adipose tissue and the calf as well as on plasma glycerol, an indicator of lipolysis, were studied in healthy volunteers. Adipose tissue blood flow was determined by the local clearance of 99mTcO-4 or 133Xe. The two isotopes gave similar results. Calf blood flow was determined by venous occlusion plethysmography. Intravenous infusion of NE caused increases in systolic and diastolic blood pressures, adipose tissue and calf vascular resistances, and plasma glycerol and a decrease in plasma insulin and heart rate, all of which were significant when arterial plasma NE was elevated from 1.17 +/- 0.14 to 8.38 +/- 0.30 nM (n = 16). Epi reduced diastolic and mean arterial pressures and adipose tissue and calf vascular resistances and increased plasma glycerol without affecting systolic blood pressure or plasma insulin. An increase of arterial plasma Epi from 0.20 +/- 0.03 to 1.15 +/- 0.05 nM (n = 6) was sufficient to induce vasodilatation in adipose tissue and lipolysis. Human adipose tissue differs from canine adipose tissue inasmuch as Epi causes vasodilatation in humans (present results) but vasoconstriction in the dog (previous results), presumably due to a predominance of vascular beta 2-adrenoceptors in human and beta 1-adrenoceptors in canine adipose tissue. Furthermore, Epi is a considerably more potent lipolytic hormone than NE in humans but not in the dog. Our results indicate that both NE and Epi may influence human adipose tissue blood flow and lipolysis as circulating hormones.

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