Impact of counterfeit medicines

2020 ◽  
Author(s):  
◽  
Keyword(s):  
Counterfeit Medicines

scholarly journals Proof-of-Concept of Detection of Counterfeit Medicine through Polymeric Materials Analysis of Plastics Packaging

Polymers ◽  
2021 ◽  
Vol 13 (13) ◽  
pp. 2185
Author(s):  
Mohammad Salim ◽  
Riyanto Teguh Widodo ◽  
Mohamed Ibrahim Noordin
Keyword(s):  
Polymeric Materials ◽  
Proof Of Concept ◽  
Scanning Calorimetry ◽  
Counterfeit Drug ◽  
Drug Products ◽  
Counterfeit Medicines ◽  
Counterfeit Medicine ◽  
Counterfeit Pharmaceuticals ◽  
Purge Gas ◽  
Sample Set

The detection of counterfeit pharmaceuticals is always a major challenge, but the early detection of counterfeit medicine in a country will reduce the fatal risk among consumers. Technically, fast laboratory testing is vital to develop an effective surveillance and monitoring system of counterfeit medicines. This study proposed the combination of Attenuated Total Reflectance Fourier Transform Infrared (ATR-FTIR) and Differential Scanning Calorimetry (DSC) for the quick detection of counterfeit medicines, through the polymer analysis of blister packaging materials. A sample set containing three sets of original and counterfeit medicine was analyzed using ATR-FTIR and DSC, while the spectra from ATR-FTIR were employed as a fingerprint for the polymer characterization. Intending to analyze the polymeric material of each sample, DSC was set at a heating rate of 10 °C min−l and within a temperature range of 0- 400 °C, with nitrogen as a purge gas at a flow rate of 20 ml min−an. The ATR-FTIR spectra revealed the chemical characteristics of the plastic packaging of fake and original medicines. Further analysis of the counterfeit medicine’s packaging with DSC exhibited a distinct difference from the original due to the composition of polymers in the packaging material used. Overall, this study confirmed that the rapid analysis of polymeric materials through ATR-FTIR and comparing DSC thermograms of the plastic in their packaging effectively distinguished counterfeit drug products.

Counterfeit medicines as global treat

2010 ◽  
Vol 12 (3,4) ◽  
pp. 179-192
Author(s):  
Maria Dolores Cabezas
Keyword(s):  
Counterfeit Medicines

scholarly journals An Investigation into the Quality of Medicines in Yangon, Myanmar

Pharmacy ◽  
2018 ◽  
Vol 6 (3) ◽  
pp. 96 ◽  
Author(s):  
Md. Islam ◽  
Naoko Yoshida ◽  
Kazuko Kimura ◽  
Chisana Uwatoko ◽  
Mohammad Rahman ◽  
...  
Keyword(s):  
Poor Quality ◽  
Cefuroxime Axetil ◽  
Quality Analysis ◽  
Content Uniformity ◽  
Counterfeit Medicines ◽  
Ceftriaxone Sodium ◽  
Substandard Medicines ◽  
Dissolution Tests ◽  
Microbial Assay

Many poor-quality medicines are supplied to patients mainly in developing countries. No systematic survey on counterfeit medicines has been conducted in Myanmar since 1999. The purpose of this study was to investigate the current situation of substandard or counterfeit medicines in Myanmar. Samples of oral medicines, cefuroxime axetil (CXM), donepezil hydrochloride (DN) and omeprazole (OM), and injections, ceftriaxone sodium (CTRX), and gentamicin sulfate (GM), were collected from pharmacies, hospitals, and wholesalers in Yangon, Myanmar in 2014. Authenticity and quality were verified. There were 221 (94%) foreign medicines among 235 collected samples. Five samples of GM and 1 DN sample were not registered with the Food and Drug Administration, Myanmar. In quality analysis, 36 samples out of 177 (20.3%) did not pass quantity tests, 27 samples out of 176 (15.3%) did not pass content uniformity tests, and 23 out of 128 samples (18.0%) did not pass dissolution tests. Three of the unregistered GM samples failed in both identification and microbial assay tests. Counterfeit GM is being sold in Yangon. Also, the quality of OM is a matter of concern. Poor-quality medicines were frequently found among the products of a few manufacturers. Regular surveys to monitor counterfeit and substandard medicines in Myanmar are recommended.

scholarly journals Combatting Substandard and Counterfeit Medicines in the Nigerian Drug Market: How Industrial Pharmacists Can Rise Up to the Challenge

2021 ◽  
Vol 12 (3) ◽  
pp. 15
Author(s):  
Melody Okereke ◽  
Ignatius Anukwu ◽  
Sola Solarin ◽  
Mazi Sam Ohuabunwa
Keyword(s):  
Law Enforcement ◽  
Drug Market ◽  
Pharmaceutical Manufacturing ◽  
Surveillance Systems ◽  
Drug Markets ◽  
Law Enforcement Agencies ◽  
Cross Border ◽  
Counterfeit Medicines ◽  
Detection Technology ◽  
Monitoring And Surveillance

Substandard and counterfeit medicines (SCMs) are a major public health threat in Africa. In Nigeria, the manufacture and distribution of substandard and counterfeit medicines in the drug market are booming, despite the efforts of law enforcement agencies to crack down on criminal syndicates over the years. The current situation has been exacerbated due to factors tied to unregulated open drug markets, lack of counterfeit detection technology, poor local pharmaceutical manufacturing capacity, and porous cross-border monitoring and surveillance systems. However, industrial pharmacists have a key role to play in combatting the production and circulation of SCMs in the Nigerian drug market. In this commentary, we examine the prevalence of SCMs in Nigeria and proffer feasible recommendations that industrial pharmacists can leverage to ensure its effective containment.

Counterfeit Medicines in Nigeria

2011 ◽  
pp. 267-278
Author(s):  
Marc J. Roberts ◽  
Michael R. Reich
Keyword(s):  
Counterfeit Medicines

Detection of Counterfeit Medicines Using Hyperspectral Sensing

2020 ◽  
Author(s):  
Sujit R Shinde ◽  
Karan Bhavsar ◽  
Sanjay Kimbahune ◽  
Sundeep Khandelwal ◽  
Avik Ghose ◽  
...  
Keyword(s):  
Counterfeit Medicines ◽  
Hyperspectral Sensing

Investigating Counterfeit Medicines—The near Infrared Chemical Imaging Picture

NIR news ◽  
2011 ◽  
Vol 22 (3) ◽  
pp. 10-18 ◽  
Author(s):  
Marta B. Lopes ◽  
Jean-Claude Wolff ◽  
José M. Bioucas-Dias ◽  
Mário A.T. Figueiredo
Keyword(s):  
Near Infrared ◽  
Chemical Imaging ◽  
Counterfeit Medicines

Chemometrics and the identification of counterfeit medicines—A review

2016 ◽  
Vol 127 ◽  
pp. 112-122 ◽  
Author(s):  
B. Krakowska ◽  
D. Custers ◽  
E. Deconinck ◽  
M. Daszykowski
Keyword(s):  
Counterfeit Medicines

Anti-Counterfeit Technologies for Spurious Drugs in India

2011 ◽  
Vol 1 (4) ◽  
pp. 42-52 ◽  
Author(s):  
Ruchi Dass ◽  
Bharat Gajjar
Keyword(s):  
Supply Chain ◽  
Supply Chain Management ◽  
Data Collection ◽  
Disease Surveillance ◽  
Mobile Radio ◽  
Counterfeit Drugs ◽  
Chain Management ◽  
Counterfeit Medicines ◽  
The World ◽  
Negative Publicity

The problem of counterfeit drugs in India has led to significant negative publicity around the world. In this paper, the author discusses how mobile/radio based and other technologies are not only helping educate people on how to check counterfeit medicines and supply chain management, but also promoting disease surveillance and spurious drugs data collection.

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