Hardware improvement in cold pressor test and Peltier system for measurement of hemodynamic response to pain by fNIR spectroscopy

Introdução: A crioterapia é um recurso que diminui a temperatura corporal local com finalidades terapêuticas. Uma importante repercussão é a vasoconstrição local, que seria o desencadeador de um possível aumento na pressão arterial (PA). Entretanto, não existem trabalhos que comprovem essa suposição. Nossa hipótese é que os resultados das pesquisas de Cold Pressor Test (CPT) avaliando PA acabaram historicamente fundamentando as precauções da crioterapia em relação a pacientes hipertensos. Objetivo: Realizar uma revisão de literatura a respeito das pesquisas que sustentam a precaução da crioterapia em indivíduos hipertensos e verificar sua relação com estudos que utilizaram o CPT. Material e métodos: Trata-se de uma revisão de literatura que utilizou as bases de dados online Medline, Scielo, Lilacs e Google Acadêmico para a realização da pesquisa. Resultado: Apesar de não serem unânimes, diversas pesquisas que utilizaram o CPT encontraram significativos aumentos da atividade nervosa simpática muscular e da PA em normotensos e hipertensos, entretanto não encontramos estudos que tenham comprovado respostas significativas de PA com o uso da crioterapia, principalmente, em hipertensos. Conclusão: Não existem evidências científicas que comprovem a precaução da crioterapia em indivíduos hipertensos. Além disso, os estudos com CPT não são unânimes em relação aos aumentos pressóricos em indivíduos normotensos e hipertensos.Palavras-chave: crioterapia, hemodinâmica, hipertensão, pressão arterial.

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Correlation of Anxiety& Cold Pressor Test in Young Adults

PARIPEX-INDIAN JOURNAL OF RESEARCH ◽

10.15373/22501991/feb2014/70 ◽

2012 ◽

Vol 3 (2) ◽

pp. 210-211

Author(s):

Anuradha Iyer Rajan ◽

Keyword(s):

Young Adults ◽

Cold Pressor Test ◽

Cold Pressor ◽

Pressor Test

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Effect of Cold Stress and the Cold Pressor Test on Blood Pressure and Heart Rate

International Archives of BioMedical and Clinical Research ◽

10.21276/iabcr.2016.2.2.14 ◽

2016 ◽

Vol 2 (2) ◽

Cited By ~ 1

Author(s):

Hajra Banoo

Keyword(s):

Blood Pressure ◽

Heart Rate ◽

Cold Stress ◽

Cold Pressor Test ◽

Cold Pressor ◽

Pressor Test

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The expanding role of the cold pressor test: a brief history

Clinical Autonomic Research ◽

10.1007/s10286-021-00796-4 ◽

2021 ◽

Author(s):

Guillaume Lamotte ◽

Christopher J. Boes ◽

Phillip A. Low ◽

Elizabeth A. Coon

Keyword(s):

Cold Pressor Test ◽

Cold Pressor ◽

Pressor Test

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The tolerance to stretch is linked with endogenous modulation of pain

Scandinavian Journal of Pain ◽

10.1515/sjpain-2020-0010 ◽

2021 ◽

Vol 0 (0) ◽

Author(s):

Morten Pallisgaard Støve ◽

Rogerio Pessoto Hirata ◽

Thorvaldur Skuli Palsson

Keyword(s):

Range Of Motion ◽

Pain Sensitivity ◽

Cold Pressor Test ◽

Cold Pressor ◽

Static Stretch ◽

Pain Thresholds ◽

Pressure Pain ◽

Pressor Test ◽

Pressure Pain Thresholds ◽

Exercise Induced

Abstract Objectives The effect of stretching on joint range of motion is well documented, and although sensory perception has significance for changes in the tolerance to stretch following stretching the underlining mechanisms responsible for these changes is insufficiently understood. The aim of this study was to examine the influence of endogenous pain inhibitory mechanisms on stretch tolerance and to investigate the relationship between range of motion and changes in pain sensitivity. Methods Nineteen healthy males participated in this randomized, repeated-measures crossover study, conducted on 2 separate days. Knee extension range of motion, passive resistive torque, and pressure pain thresholds were recorded before, after, and 10 min after each of four experimental conditions; (i) Exercise-induced hypoalgesia, (ii) two bouts of static stretching, (iii) resting, and (iv) a remote, painful stimulus induced by the cold pressor test. Results Exercise-induced hypoalgesia and cold pressor test caused an increase in range of motion (p<0.034) and pressure pain thresholds (p<0.027). Moderate correlations in pressure pain thresholds were found between exercise-induced hypoalgesia and static stretch (Rho>0.507, p=0.01) and exercise-induced hypoalgesia and the cold pressor test (Rho=0.562, p=0.01). A weak correlation in pressure pain thresholds and changes in range of motion were found following the cold pressor test (Rho=0.460, p=0.047). However, a potential carryover hypoalgesic effect may have affected the results of the static stretch. Conclusions These results suggest that stretch tolerance may be linked with endogenous modulation of pain. Present results suggest, that stretch tolerance may merely be a marker for pain sensitivity which may have clinical significance given that stretching is often prescribed in the rehabilitation of different musculoskeletal pain conditions where reduced endogenous pain inhibition is frequently seen.

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Contactless analysis of heart rate variability during cold pressor test using radar interferometry and bidirectional LSTM networks

Scientific Reports ◽

10.1038/s41598-021-81101-1 ◽

2021 ◽

Vol 11 (1) ◽

Author(s):

Kilin Shi ◽

Tobias Steigleder ◽

Sven Schellenberger ◽

Fabian Michler ◽

Anke Malessa ◽

...

Keyword(s):

Heart Rate ◽

Heart Rate Variability ◽

Dynamic Change ◽

Cold Pressor Test ◽

Cold Pressor ◽

Contactless Measurement ◽

Pressor Test ◽

Skin Contact ◽

Bidirectional Lstm ◽

Lstm Network

AbstractContactless measurement of heart rate variability (HRV), which reflects changes of the autonomic nervous system (ANS) and provides crucial information on the health status of a person, would provide great benefits for both patients and doctors during prevention and aftercare. However, gold standard devices to record the HRV, such as the electrocardiograph, have the common disadvantage that they need permanent skin contact with the patient. Being connected to a monitoring device by cable reduces the mobility, comfort, and compliance by patients. Here, we present a contactless approach using a 24 GHz Six-Port-based radar system and an LSTM network for radar heart sound segmentation. The best scores are obtained using a two-layer bidirectional LSTM architecture. To verify the performance of the proposed system not only in a static measurement scenario but also during a dynamic change of HRV parameters, a stimulation of the ANS through a cold pressor test is integrated in the study design. A total of 638 minutes of data is gathered from 25 test subjects and is analysed extensively. High F-scores of over 95% are achieved for heartbeat detection. HRV indices such as HF norm are extracted with relative errors around 5%. Our proposed approach is capable to perform contactless and convenient HRV monitoring and is therefore suitable for long-term recordings in clinical environments and home-care scenarios.

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Effect of short-term smoking & L-arginine on coronary endothelial function assessed by cardiac magnetic resonance cold pressor testing: a pilot study

BMC Cardiovascular Disorders ◽

10.1186/s12872-021-02050-1 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Andreas M. Weng ◽

Herbert Köstler ◽

Thorsten A. Bley ◽

Christian O. Ritter

Keyword(s):

Magnetic Resonance ◽

Imaging Techniques ◽

Cold Pressor Test ◽

Cold Pressor ◽

Short Term ◽

Pressor Test ◽

Coronary Vasomotion ◽

Short And Long Term ◽

Coronary Endothelium

Abstract Background The effect of smoking on coronary vasomotion has been investigated in the past with various imaging techniques in both short- and long-term smokers. Additionally, coronary vasomotion has been shown to be normalized in long-term smokers by L-Arginine acting as a substrate for NO synthase, revealing the coronary endothelium as the major site of abnormal vasomotor response. Aim of the prospective cohort study was to investigate coronary vasomotion of young healthy short-term smokers via magnetic resonance cold pressor test with and without the administration of L-Arginine and compare obtained results with the ones from nonsmokers. Methods Myocardial blood flow (MBF) was quantified with first-pass perfusion MRI on a 1.5 T scanner in healthy short-term smokers (N = 10, age: 25.0 ± 2.8 years, 5.0 ± 2.9 pack years) and nonsmokers (N = 10, age: 34.3 ± 13.6) both at rest and during cold pressor test (CPT). Smokers underwent an additional examination after administration of L-Arginine within a median of 7 days of the naïve examination. Results MBF at rest turned out to be 0.77 ± 0.30 (smokers with no L-Arginine; mean ± standard deviation), 0.66 ± 0.21 (smokers L-Arginine) and 0.84 ± 0.08 (nonsmokers). Values under CPT were 1.21 ± 0.42 (smokers no L-Arginine), 1.09 ± 0.35 (smokers L-Arginine) and 1.63 ± 0.33 (nonsmokers). In all groups, MBF was significantly increased under CPT compared to the corresponding rest examination (p < 0.05 in all cases). Additionally, MBF under CPT was significantly different between the smokers and the nonsmokers (p = 0.002). MBF at rest was significantly different between the smokers when L-Arginine was given and the nonsmokers (p = 0.035). Conclusion Short-term smokers showed a reduced response to cold both with and without the administration of L-Arginine. However, absolute MBF values under CPT were lower compared to nonsmokers independently of L-Arginine administration.

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