Volumetric and Growth Changes induced by serial casting treatment of congenital clubfoot on tarsal bones

2021 ◽  
Author(s):  
Phitha Philip
Keyword(s):  
Congenital Clubfoot ◽  
Serial Casting ◽  
Tarsal Bones ◽  
Growth Changes

Volume of tarsal bones in congenital clubfoot

1997 ◽  
Vol 2 (1) ◽  
pp. 3-9 ◽  
Author(s):  
Masaki Hata ◽  
Akinori Nango ◽  
Hisateru Niki ◽  
Yoshifumi Hayafune ◽  
Atsushi Kato
Keyword(s):  
Congenital Clubfoot ◽  
Tarsal Bones

Onset of Ossification of the Tarsal Bones in Congenital Clubfoot

1997 ◽  
Vol 17 (1) ◽  
pp. 36-40 ◽  
Author(s):  
Noboru Miyagi ◽  
Hideo Iisaka ◽  
Kazunori Yasuda ◽  
Kiyoshi Kaneda
Keyword(s):  
Congenital Clubfoot ◽  
Tarsal Bones

scholarly journals Bilateral idiopathic club foot in baby of a rheumatoid mother: A rare case report and its management

2021 ◽  
Vol 7 (1) ◽  
pp. 46-49
Author(s):  
Ranjeet Choudhary ◽  
Alok Chandra Agrawal ◽  
Anupam Pradip Inamdar ◽  
Pandya Raj ◽  
Shilp Verma
Keyword(s):  
Rheumatoid Arthritis ◽  
Club Foot ◽  
Rare Case ◽  
Deformity Correction ◽  
Idiopathic Clubfoot ◽  
Casting Method ◽  
Congenital Clubfoot ◽  
Pirani Score ◽  
Serial Casting ◽  
Female Baby

Congenital clubfoot has a multifaceted etiology, with several hypotheses offered in its etiopathogenesis. The clubfoot has rarely been reported in babies born to women who have rheumatoid arthritis (RA). We present a rare case of a 31-year-old lady with RA on disease-modifying anti-rheumatoid drugs who delivered a child with bilateral congenital clubfoot. She had previously been using Methotrexate, Hydroxychloroquine, and Sulfasalazine regularly, but Methotrexate was stopped seven months before pregnancy. A full-term female baby was born through the cesarean section with bilateral clubfoot deformity and a modified Pirani score of eight out of 10. The deformity correction was done with the Ponseti serial casting method. The final modified Pirani score was two out of ten. In newborns born to rheumatoid arthritis mothers, the club foot deformity was effectively treated with serial Ponseti corrective casts, as was idiopathic clubfoot in babies born to non-rheumatoid mothers. Our findings validate the Ponseti serial casting method for these kinds of patients.

Morphometric Studies on The Tarsal Bones of Blue Bull (Boselaphus tragocamelus

2016 ◽  
Vol 12 (2) ◽  
Author(s):  
Sanjay Kumar Bharti ◽  
Ishwer Singh ◽  
Balwinder Singh Dhote ◽  
Om Prakash Choudhary ◽  
Meena Mrigesh
Keyword(s):  
Average Height ◽  
Internal Part ◽  
Tarsal Bones ◽  
Single Bone

A study was carried out on the tarsal bones of blue bull. The tarsus of blue bull consisted of five bones i.e., tibial tarsal (Astragalus), fibular tarsal (Oscalcis), fused central and fourth tarsal (Scaphocuboid), first tarsal (Cunciformparvum) and second and third tarsal fused (Cuseiform magnum).The average height and breadth of tibial tarsal was 6.81±0.01 cm and 3.84±0.01 cm, respectively. The fibular tarsal was the longest, elongated bone of the tarsus and flattened from side to side with an average height and breadth 12.00±0.01 cm and 3.72±0.01 cm, respectively. The central and the fourth tarsalswere fused together to form a large single bone. The average height and breadth for central and fourth fused tarsal was 2.54±0.01 cm and 5.11±0.01 cm, respectively. The first tarsal was a quadrilateral piece of bone placed at the postero-internal part of the tarsus. The length and maximum breadth of first tarsal was 2.14±0.01 cm and 3.32±0.01 cm, respectively. The second and third fused tarsal was a small plate of bone having length and breadth of second and third fused tarsal 1.68±0.01 cm and 3.34±0.01 cm, respectively.

Hair Growth in a Patient with Alopecia Areata on Tocilizumab

2021 ◽  
pp. 1-5
Author(s):  
Chloe J. Walker ◽  
Kelly E. Flanagan ◽  
James T. Pathoulas ◽  
Isabel Pupo Wiss ◽  
Maryanne M. Senna
Keyword(s):  
Monoclonal Antibody ◽  
Autoimmune Disease ◽  
Hair Loss ◽  
Alopecia Areata ◽  
Interleukin 6 ◽  
Hair Growth ◽  
Posterior Uveitis ◽  
Case Presentation ◽  
Antibody Targeting ◽  
Growth Changes

<b><i>Introduction:</i></b> Tocilizumab (TCZ), a recombinant humanized antihuman monoclonal antibody targeting interleukin-6 (IL-6) signaling, is often utilized in the management of autoimmune disease. Few reports have demonstrated hair growth changes in patients on TCZ. <b><i>Case Presentation:</i></b> Herein, we review the literature and report a 21-year-old woman with progressive alopecia areata (AA) presenting with AA improvement while on TCZ for concomitant posterior uveitis. <b><i>Discussion:</i></b> Our case demonstrates the potential ability of TCZ to disrupt IL-6 signaling involved in AA, leading to hair loss and regrowth.

scholarly journals Spondylocarpotarsal synostosis syndrome due to a novel loss of function FLNB variant: a case report

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Samina Yasin ◽  
Outi Makitie ◽  
Sadaf Naz
Keyword(s):  
Short Stature ◽  
Autosomal Recessive ◽  
Autosomal Recessive Disorder ◽  
Loss Of Function ◽  
Case Presentation ◽  
Pathogenic Variants ◽  
Skeletal Malformations ◽  
Tarsal Bones ◽  
The Family ◽  
Heterozygous Carriers

Abstract Background Loss of function or gain of function variants of Filamin B (FLNB) cause recessive or dominant skeletal disorders respectively. Spondylocarpotarsal synostosis syndrome (SCT) is a rare autosomal recessive disorder characterized by short stature, fused vertebrae and fusion of carpal and tarsal bones. We present a novel FLNB homozygous pathogenic variant and present a carrier of the variant with short height. Case presentation We describe a family with five patients affected with skeletal malformations, short stature and vertebral deformities. Exome sequencing revealed a novel homozygous frameshift variant c.2911dupG p.(Ala971GlyfsTer122) in FLNB, segregating with the phenotype in the family. The variant was absent in public databases and 100 ethnically matched control chromosomes. One of the heterozygous carriers of the variant had short stature. Conclusion Our report expands the genetic spectrum of FLNB pathogenic variants. It also indicates a need to assess the heights of other carriers of FLNB recessive variants to explore a possible role in idiopathic short stature.

Load Response of the Tarsal Bones in Patients with Flatfoot Deformity: In Vivo 3D Study

2011 ◽  
Vol 32 (11) ◽  
pp. 1017-1022 ◽  
Author(s):  
Masamitsu Kido ◽  
Kazuya Ikoma ◽  
Kan Imai ◽  
Masahiro Maki ◽  
Ryota Takatori ◽  
...  
Keyword(s):  
Load Condition ◽  
Clinical Analysis ◽  
Biomechanical Analysis ◽  
Talonavicular Joint ◽  
Level Of Evidence ◽  
Tibiotalar Joint ◽  
Talocalcaneal Joint ◽  
Load Response ◽  
Tarsal Bones

Background: The objective of this study was to evaluate the bone rotation of each joint in the hindfoot and compare the load response in healthy feet with that in flatfeet by analyzing the reconstructive three-dimensional (3D) CT image data during weightbearing. Methods: CT scans of 21 healthy feet and 21 feet with flatfoot deformity were taken in non-load condition followed by full-body weightbearing load condition. The images of the hindfoot bones were reconstructed into 3D models. The volume merge method in three planes was used to calculate the position of the talus relative to the tibia in the tibiotalar joint, the navicular relative to the talus in talonavicular joint, and the calcaneus relative to the talus in the talocalcaneal joint. Results: The talar position difference to the load response relative to the tibia in the tibiotalar joint in a flatfoot was 1.7 degrees more plantarflexed in comparison to that in a healthy foot ( p = 0.031). The navicular position difference to the load response relative to the talus in the talonavicular joint was 2.3 degrees more everted ( p = 0.0034). The calcaneal position difference to the load response relative to the talus in the talocalcaneal joint was 1.1 degrees more dorsiflexed ( p = 0.0060) and 1.7 degrees more everted ( p = 0.0018). Conclusion: Referring to previous cadaver study, regarding not only the cadaveric foot, but also the live foot, joint instability occurred in the hindfoot with load in patients with flatfoot. Clinical Relevance: The method used in this study might be applied to clinical analysis of foot diseases such as the staging of flatfoot and to biomechanical analysis to evaluate the effects of foot surgery in the future. Level of Evidence: III

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